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When you see all the data flowing in regarding “Died Suddenly”….do you ask yourself if maybe   Common sense died suddenly first….  or   Critical thinking died suddenly…..after being injected by propaganda?

The centralized paradigm thinks biology is driven by a DNA paradigm.  Decentralized medicine is driven by the other genome, the mitochondrial genome that responds to the thermodynamic situation of the environment.

I have chosen the team I play on.  It is up to you to decided your team.

DUE DILIGENCE OF YOUR CHOICE

Modern epidemics are not caused by genetics, but by epigenetics!

This is also a clinical medical fact that gets lost in the modern scientific literature but you would never get that from reading the literature on diabetes or any other neolithic disease. In fact the totality of the diabetes literature would have you believe the exact opposite. This is a centralized neolithic thought that has harmed all modern diabetics and is at the seat of why modern medicine has failed to find a cure.

Mother Nature has a cure for insulin resistance in all eutherian mammals. That answer is thermodynamic.  It is mitochondrial based and has nothing to do with defective RNA/DNA.  Your choice need to change so that they marry strong solar power with night time cooling by avoiding all heating and lighting at dark.  Nature & decentralized medicine is non negiotiable with this prescription.

That is cold exposure of there peripheral nervous systems, is critical in informing the brain what probabilities should happen at night.  Artificial light at night changes the probabilities when a human makes the wrong choice.

The stimulus to this pathway begins when the mammal is exposed to a high dietary carbohydrate diet that is found in long light cycles on this planet.  It is magnified at higher latitudes.  It is minimized at the equator.  The truth is found in mitochondria haplotypes. The electromagnetic signal of Earth informs the cell that the membranes need to adapt to cooler temperatures.  This is why certain haplotypes exist in different latitudes.

This is how the gut senses the environment and this signals are transmitted to the brain via the vagus nerve. Centralized healthcare & modern biochemistry books and biochemists stop here at this level of understanding.  YOU MUST GO FURTHER.

Their beliefs are built by what THEY believe they know about energy transformation in cells. But I always focus in on what they have failed to realize.

When dietary carbohydrates are high it stimulates the eutherian mammal to begin to upregulate omega 6 content into every cell membrane of their body slowly through the autumn while temperature falls. It speeds up as the temperature drops in winter. This process is completely independent of dietary sources as I laid out in the Cold Thermogenesis #3 blog.

Why does this occur in all mammals?

People forget that lipid membranes are objects in cells that are very sensitive to electromagnetic signals.  The proof is found in how membranes are built and vary via temperature variation. For example, in mammalian cells, the plasma membrane cytoplasmic leaflet usually contains more phosphatidylethanolamine (PE) and phosphatidylserine (PS) when compared with the outer leaflet rich in sphingolipids.  There is an electromagnetic reason for this.  The phosphate groups in membrane phospholipids bind strongly to water because they are hydrogen (proton acceptors).  This singular fact suggests that light signals activate the membranes.  The membrane alters the hydration and dehydration of proteins and metabolites and in turn are critically important in activation control and deactivation of all the biochemical pathways in cells.  These are choices made by light and temperature variation.  That is why crcadian biology is the key to recapturing your health.

Maintenance of membrane fluidity by DHA incorporation, despite the presence of saturated lipids, is sustained by integrated sterols that interfere with acyl chain packing.  This mixture changes its electrical conductance and impedience.  Membranes vary the reactivity to light.  It is like cells can change the semiconductors they use as seasons change.  Those changes are signaled to water below the cell level. Conversely, because sterols themselves are inflexible they can increase membrane rigidity if associated with flexible unsaturated lipid bilayer. It is worth noting that cholesterol deposition can similarly be asymmetrical and differs greatly among organelles and in tissues in mammals.  Mammals are highly adaptable to environmental variation.

Because to cell membranes to function in cold weather it requires all land based mammals from cold adapted ancestors to have an EFA ratio of 4:1 for optimal signaling. In water based mammals who are cold adapted, like whales, walrus, and seals, humans they face steeper temperature gradients in the water that require a much lower EFA ratio (essential fatty acids) in their cell membranes to function properly.  Water transmits heat changes 24 times faster than air does.  This is why temperature variation matters in decentralized prescriptions of disease reversal.  To see this effect look at what heavy use of the AC power grid did in Spain to annual birth rhythms of humans.  Does this look like the scientific reason of what happened in John Calhoun’s Universe 25 experiments done in labs over and over again?

This lowered ratio of EFAs also changes the biology of adipocyte biochemistry below the skin level where light enters the body. It favors the accumulation of surface fat but not of visceral fat. Visceral fat is used to burn first to maintain core temperature in these animals. In land based cold adapted mammals like the polar bear the same is true. When they emerge from their den in spring they are shredded of all visceral fat and no longer insulin resistant, and have the biggest and strongest muscles they will have all year. Their body composition is at its best at this time. They accomplish all this without needing any exercise to do it.  Do polar bears or any other animal but humans have indoor lit gyms?

This is in counter distinction to modern man beliefs. Why is this? The question is more complicated than the answer, but the answer is again, simple.  It is simple because it is based in decentralized wisdom.  Light and dark control the circadian mechanism.

Modern man is further down the evolutionary path because its optical lattice clock in the eye is best atomic clock on the planet.  Everything should be thought of clock.  Humans have the most accurate timepiece of any mammal on Earth.  But its accuracy is ruined when its periodicity of light and dark is disrupted.  Better clocks mean it can support a faster evolution.  Fast evolution has another name.  It is called epigenetics.  In offspring it is called transgenerational epigenetics.

This implies in mammals, after the KT event, evolutionary development was the product of a sped up epigenetic process. Photosynthesis was disrupted.  The next generation of mammals had to quickly adapt so they could navigate this changing environment.  Life faced this before at the Cambrian explosion as I showed in my Vermont 2019 talk.  The sun changed 650 million years ago before complex life forms showed up on Earth.  Light sculpts all life.  It is not arguable any longer.

The rapid changes in the environment had to be transmited to the next generation to guarrantee survival.  The reason was due to massive environmental changes that occured due to the dsruption of photosynthesis of the KT event.

The KT event subtracted UV light from the thermodynamics of life.

This made the environment colder at most latitudes for many years after the event.  In essence, the electromagnetic response of complex cells to an extinction level event was to speed up epigenetics over time.  This wass a complex thermodynamic response to a lack of sunlight.  This negative, set the tone for future human evolution.  These environmental actions 65 million years ago allowed for the human brain to develop faster 2.5 million years ago because cellular machinery us were adapted in our epigenetic tool box to build a more complex body plan when the sun returned for mammals.  It advanced epigenetic evolution because he sun returned with photosynthesis yield post KT event.

With photosynthesis back our diet once again became an electromagnetic bar code for latitude and tectonic plate motions.  The return of UV light gave us a new way to deplete deuterium further because of the epigenetic changes that caused our mammalian mitochondria to become efficient at depleting it from foods.  UV light is critical in depleting deuterium in mammalian cells.  Look at the absorption spectra of proteins compared to the electromagnetic spectrum of light.

This allowed our cell membranes to signal both electric and magnetic field strength to the interior of cells where our mitochondrial reside.  As a result, our diet radical changed again from our immediate ancestors, the chimpanzee.

This ability caused two simultaneous evolutionary adaptations to occur simultaneously. As our brain expanded, our guts shrunk in length. We only needed a smaller gut when we become adapted to eat predominantly fat and protein from marine animals.  This diet built a faster clock because of the effect of DHA on the central retinal pathways.  This made our eye clock wildly sensitive to changes in environmental light.  This was a benefit that drove hominid evolution but now it has become our major weakness as a species.

Man made light destroys mitochondrial redox by lowering cell voltages on the inner mitochondrial membrane.

After the KT event, our SCN became a better optical lattice clock with the return of full powered terrestrial sunlight.   A diet high in fat and protein was also used to fuel encephalization of hominids. DHA in the marine chain was critical in this change.  Larger brains meant we needed pelvic changes to become bipedal and it also extinguished the need to hibernate. Hibernation needs were shrunk from seasonal changes into our sleep cycle during stage 3 and 4 sleep. As we became smarter (DHA infusions in eye and frontal lobes) we became able to not only react better to electromagnetic signals in our environment, but we became able to control our environment. We changed light in our environment because of how our brain adapted.  This is how a sped up epigenetic plan set up modern man to become more susceptible to many biochemical mismatches.

SUMMARY

When our recent ancestors lost the ability to hibernate, they also lost their best way to fight insulin resistance. Since those ancestor mammals ate carbohydrates in a proper circadian cycles, purely controlled by their seasonal growth, the biochemical systems in those mammals readily adapted to these new states without much problem. This biologic adaptation required alteration of the leptin receptor to function with higher levels of cytokines present. It appears natural selection also made adjustments to liver biochemistry and bioenergergenics to mirror those changes made in the brain.

Every eutherian mammal born on this planet up until 2.5 million years ago had to live by the dictums of their environment. When hominids evolved, much later, this environmental situation radically was altered. Hominids remain the only mammal on the planet who can 100% control its own environment. This allows our species to create mismatches at even a  great speed, as our brain continued to develop over the last 2.5 million years. This trend dramatically speeds up all our chemical clocks in every cell of our body that is controlled by circadian biology. This is well known by modern science, but its implications are IGNORED.

The Nobel Prize of 2009 tied this all to telomere lengths in our cells. The 2017 Nobel was given for circadian biology.  It is time you all pressure centralized healthcare to begin working for you and how biology works and stop supporting centralized healthcare that works for Big Pharma and Big Food.

All mammals have circadian signaling hardware in their brains that wire directly to the cell cycle machinery in every single cell of their bodies. This means that modern hominids are the most sensitive mammal to any circadian mismatch compared to their ancestors. Moreover, since they have the most advanced brain in the mammalian family, they are subjected to the greatest risk of neolithic diseases due to these mismatches. Humans get diseases that no other wild animal gets for this reason. Humans get autoimmune disease when our most recent ancestors, the chimp can not. They do not have zonulin and we do. This is one of the most fundamental reasons why our guts are adapted to different diets that lead to our encephalization. Animals domesticated by humans suffer the same fates as we do, ironically. Wild mammals tend not to get these issues because they live by the rule that Mother Nature determines for them in their own selected environments.

The ultimate paradox of modern hominids is that they evolved the ability to live on a warm adapted diet and in a warm environment, but that they retain the cold adapted biochemistry buried in their brains even though they do not need to use it presently. Evolution has not extinguished this ability for a very good reason, in my view. Mammals survived an extinction event because of it.  One reason is that the geologic record shows that our planet undergoes cyclic cooling and warming over longer epochs. This will keep the pathway active epigenetically over thousands of years.

The main reason it has not been extinguished in my opinion, is that this ancient pathway determines ultimate survival of the mammalian species and it was vital at one time in evolutionary history. Modern hominids have an advanced nervous system, but they still are tied to the evolutionary family they came from long ago. They are not divorced from the rules of Mother Nature even though they act as if they are. This ties modern humans directly back to Factor X at the KT event. The paradox of this situation is that they remain blind to it even today.

CITES

1.  https://pubmed.ncbi.nlm.nih.gov/12562849/

2. From the file of they are waking up to my perspective:  Circadian disruption and human health: A bidirectional relationship – Abbott – – European Journal of Neuroscience – Wiley Online Library.  https://onlinelibrary.wiley.com/doi/10.1111/ejn.14298

Listening well is often the only thing needed to really help someone. No one is as deaf as the centralized man who will not listen.  You earn the right to be heard by listening to others first.  Do it carefully to understand how they think before you respond. Most folks do not listen with the intent to understand; they listen with the intent to reply.  Seek to understand a situation before judging its faults or merits.  Listen to your elder’s advice carefully. The wise do this not because they are always correct about things, but because they have more experience of being wrong.  The smartest among us always learn to avoid the pitfalls of life with via the experience of others who made the errors.  Our mode of thinking sculpts our perspective. We only see what we think about because it forms how we choose to see the world.  This is why listening is a tool of the wise.  You can dissect anyone or thing when you learn how to listen to how someone thinks.

Good circadian clock management creates lives with less volume creation and more storage at night for urine. Nature seems to want diurnal mammals to drink water prior to sleep.  The system is built for this type of behavior.  All neurons move and release water when neurons fire action potentials. Thirst is controlled by posterior pituitary vasopressin.  Vasopressin is directly acted upon by light coming in through the central retinal pathways to affect the posterior pituitary.  The posterior pituitary output affects the immune system’s ability to function.  The nervous and immune systems are engaged in bidirectional communication as the picture shows.  Vasopressin is a big part of this blueprint.

I believe all autoimmune diseases are related to the disruption of the bi-directional reflex loops you see in the pictures above.  I believe the damage begins with light we are not built for.

T-Cells are the key player in autoimmune conditions. We’ve known this since 2003. In 2016 we found out how blue light causes T-cell motility. We now have all the pieces to explain the basic mechanism of all autoimmune diseases and why it is linked to the blue hazard.  HYPERLINK

Autoreactive T lymphocytes are key players in autoimmune diseases. They can act both as regulatory and effector cells. Various animal models have been used in the literature to show that the transfer of autoreactive T cells is sufficient to induce a model of an autoimmune disease. Thus, the pathogenic importance of autoreactive T cells has been formally demonstrated in animals. This should inform centralized healthcare that autoimmunity is tied to our light choices but patients never get told this.

Robert O. Becker taught us that injured tissue elicited an electromagnetic signal to begin wound repair. He found that an electrostatic field, negative away from the limb stump, could enable the regeneration of a frog limb.  Becker ascribed regeneration capability to the existence of a nucleus in the salamander’s erythrocyte. (The mature erythrocytes of frogs and higher animals lacked a nucleus.) Erythrocytes with nuclei seemed to have the dedifferentiation capability required for later differentiating into the various cell types needed in the growth area. Becker described these studies in his 1985 book The Body Electric, and also (condensed and compared with other fields) in the first part of his 1990 book Cross Currents.

The video above also shows this effect in the animal modeling of human cell injury in trauma.

Vasopressin (AVP) is released after every type of brain injury.  All injuries cause an electromagnetic stimulus to direct repair, as Becker found in his work.  This tells us vasopressin responds to electromagnetic stimuli even outside its normal circadian cycle.  Non-terrestrial forms of light is a light stress.  It is a form of traumatic brain injury.  Light injuries have become the most common non-military injury humans get in the modern world in their neurons.

Normally vasopressin is released at night when light is not present.  Artificial light post-sunset causes massive early chronic release of vasopressin.  Screen time during the day exacerbates this.  I believe that this is critical in the development of diseases like Multiple Sclerosis.  Research has shown that people with MS respond to vasopressin antagonist drugs to heal their myelin deficits.  This tells clinicians that the chronic release of vasopressin to light stress is the key problem in this immune-mediated disease.

https://twitter.com/DrJackKruse/status/1609921221017190407

Is Nature’s clue found in vasopressin molecular structure?  They are.  Vasopressin is a posterior pituitary hormone which means it has a direct connection to the retina and the SCN.  It also is directly related to the neuroimmune system.  It tells us sunlight is the electromagnetic stimulus that vasopressin reacts to.  Vasopressin is made in an area with no blood-brain barrier telling us that it is open to the environment’s electromagnetic signal.  Vasopressin is made of 9 amino acids.  The amino acid sequence of arginine vasopressin (argipressin) is Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2, with the cysteine residues forming a disulfide bond and the C-terminus of the sequence converted to a primary amide. It has two clues it is a circadian qubit.  It contains two aromatic amino acids and it has a disulfide bond linked to its cysteine residue (re-read the orexin blog to understand the importance).

Mother Nature seems to want enough water in the system for the neurons in our brain to be able to anticipate it can follow the circadian rhythm of CSF production for the brain’s glymphatic system, and that there will be enough to not compromise autophagy.

One of his key goals is to design a sensitive vasopressin test for healthcare workers to use for people with circadian arrhythmia in the Emergency Room. If levels could be assessed rapidly, it could help physicians to understand how the body is managing water, giving clues as to how to deal with various illnesses with blue light and nnEMF exposures.  In experimental models of cardiac arrest, vasopressin increases blood flow to the heart and brain and improves long-term survival.  But vasopressin release in excess seems to be one of the things that cause chronic injury to myelin in Multiple sclerosis.  This is why Big Pharma is developing vasopressin antagonists drugs to treat it.

Why? Our modern lights dehydrate us causing us to age faster and die sooner.  Sunlight hydrates our cells.

Middle-age serum sodium >142 mmol/l is associated with a 39% increased risk of developing chronic diseases  & >144 mmol/l with a 21% elevated risk of premature mortality. People with serum sodium >142 mmol/l had up to 50% higher odds to be older than their chronological age.  High serum Na is a proxy for your Light clock management behavior at the SCN level.

Until recently (2017), it was thought to only work in a classic, negative feedback loop: when we are dehydrated (bad matrix function at CCO), levels of vasopressin rise, which causes urine to become concentrated in the kidneys, freeing up more water to be used in the body.

Conversely, when we have too much water in our body, vasopressin levels decrease, and urine is diluted. What if that is not all that vasopressin does?

Vasopressin changes the possibilities that water presents to the quantum programs that control wound healing by altering charge density in coherent domains of water.  This adaptation is done by altering the epigenetic programs in cells.

Water is the quantum stage cells play on.  Water is created by cytochrome c oxidase in the mitochondria.  The spinning Fo head of the ATPase sits adjacent to the CCO. That spinning Fo head creates a magnetic field at the subatomic level. Inside a cell, water also has a magnetic dipole effect (negative and positive ends) because of the hydrogen and oxygen that make water up.

Hydrogen is positively charged, and oxygen is negatively charged. This creates a bar magnet effect in cells. These physical features are what help water networks respond to electromagnetism and waves of light.  If you look at the vasopressin molecular structure above you’ll notice on one side of the disulfide bond there are a lot more negatively charged oxygen atoms.  This tips the magnetic flux one way to signal wounds should heal using the epigenetic programs mentioned in the video above and found in Becker’s books.

I believe vasopressin is a highly negatively charged protein that is a qubit for the quantum brain that changes epigenetic signaling in tissues.  Vasopressin is how we influence probabilities of future events in water using sunlight as a lever.  

It seems organisms use vasopressin levels to predict and prepare themselves in advance for environmental changes that have selective advantages over those who cannot accommodate themselves until the changes of the environment have taken place to cause dehydration of mitochondria for some reason.  ALAN causes massive dehydration in the mitochondrial matrix.  Doing this long-term will shorten longevity by leading to diseases like MS.

In 2017 the same researchers found vasopressin does a lot more than they thought initially. They found that not only is there a vasopressin circadian feedback loop, but “it’s also involved in feed-forward mechanisms. This is quite important in understanding from a chronobiologic perspective. They determined that this molecule is produced in the brain right before people go to bed WHEN IT IS SUPPOSED TO BE DARK, and during sleep, in anticipation of the dehydrating effect of sleep. During sleep, autophagy is supposed to be very active if you are healthy.  Vasopressin is normally released at 9 PM.  It is designed to offset the dehydrating effect of sleep.  Vasopressin is also known as an anti-diuresis hormone.

I believe vasopressin induces a negative magnetization in water networks.  What is negative magnetization?

When negative charges are added, we can find a temperature-dependent crossover of the DC magnetization from a positive value to a negative value of a material (cooled under a positive applied magnetic field) is termed the magnetization reversal or negative magnetization.  Becker found this flip in the DC magnetic field between sleep and wakefulness and between consciousness and general anesthesia.  Vasopressin helps us sleep when water creation is reduced.

Moreover, when you are recycling mitochondria during autophagy you cannot make any water at CCO. What happens if you cannot make water even in the sunlight because you’ve lost total control of autophagy because of chronic toxic blue light and nnEMF light stress?

The core skill of a successful Mitochondriac is error recovery in Nature, not failure avoidance from prior poor decisions.

There is only one way to repair that well. It means that we need SUNLIGHT IS MANDATORY to make water at CCO during the day. If you do not get enough or live at a high latitude and inside you need more water. If we do not get enough sunlight then we lose circadian feedback control of vasopressin and the entire water cycle in our body.  This is how lousy clock management leads to epigenetic disease by decreasing mitochondrial redox power.  You saw this in the petri dish picture above in the video.  A loss of redox power = disease state or injury state.

So people who are incentivized by selling DDW need to be vetted.  They have not thought this out well from the Black Swan mitochondria perspective.

Our light choices can be seen in our labs if you know what to look for.  Our light environment trumps chronological age as an epigenetic driver.
Frequent shift work results in more urination for ANY AGE because the circadian gene Rev-Erbα controls the production of Cx43, which determines how much urine a bladder holds.

TL;DR: Poor circadian rhythm = More urination = more disease = FASTER DEATH COMES = THE RELATIVITY OF TIME MODELED.

Energy and light frequencies are the only predeterminants nature needs to change water’s behavior in your cells. 

As the environment’s frequencies and power density change so do the reaction of water in you. When you begin to realize how sunlight changes in different latitudes on Earth and in different cities because of 1G-5G footprints it should begin to make sense to you why you perform differently in differing locations. Water is made at cytochrome 4 called CCO. What if that process is disrupted by the environment? Is the fidelity of the signal destroyed? Will the oscillation pattern of the inner mitochondrial membrane also change? Is this why we lose the ability to fat burn with the 100Hz oscillation needed for beta-oxidation in alien environments?

If so, does this affect how much water is made and how that water reacts within the metabolic cycles of the cell? You bet your ass it does. This is how nnEMF is operating to make you ill way below your ability to perceive it.

SUMMARY

I have found in my “internet guru career” those who are easily shocked about things or words I utter should be shocked more often in their life. This is why our brightest blazes of insight in life are really kindled by unexpected sparks of insight. Be unique and light people up because you are extraordinary in how you think.

Is drinking water post-sunset mandatory for outdoor living creatures based on what we’ve discussed here?   When humans tell you not to drink water might they be incentivized in trying to sell that belief (Boros and his DDW krewe in LA)

Canadian research showed that mammals tend to increase water intake just before sleep when sunlight is absent. Rather than being motivated by a physiological need for water, the drinking response was solely based on the animal’s circadian rhythms.  The efficiency of your circadian mechanism is critical to this mechanism working as it is designed.  Sunlight creates water, darkness doesn’t <———-BIG FREAKING DEAL ALERT.

When a cell is de-polarized it is deformed by water, and potassium is released. This normally causes a glial cell to swell. This causes a volume change in the adjacent neuron (astrocytes).

When water moves, it changes the refractive index of bulk water in the extracellular compartment of the neuron to create a large coherent domain of water within the neuron and below the myelin level. The astrocytes work as a giant drainage system for water, which uptakes potassium ions in regions with high potassium, and sends them to regions of lower potassium ion concentrations. Vasopressin changes how the drainage system operates.

Vasopressin or antidiuretic hormone, which is made in the posterior pituitary gland, allows the brain controls the flow of water to activate itself in accordance with the stimuli that it currently faces. Any trauma to neurons causes its release. Normally vasopressin is controlled by circadian stimuli. The sun normally controls the release. Artificial light is a light stressor. It causes the release of vasopressin outside of the circadian mechanism.

Fact: Blue light/nnEMF dehydrates cells because they stop H2O production from the mitochondrial TCA cycle. Why is this a big deal? Neurons absorb and release water when firing information via their action potentials. When H2O is missing in action so are neurological functions/capabilities. Check the link here.

Bai, Ruiliang. Brain-active transmembrane water cycling measured by MR is associated with neuronal activity. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.27473

The gist of this paper is that neurons absorb and release water when they relay messages throughout the brain and peripheral nervous system. Tracking this water movement with imaging technology may one day provide valuable information on normal brain activity, as well as how injury or disease affects brain function. 

The study appeared in Magnetic Resonance in Medicine.  Just how devasting is artificial light on water flowing in neurons?  4% of the world has autoimmune diseases related to the blue light hazard.  There are just over 100 human autoimmune diseases that afflict humans. 

Current functional magnetic resonance imaging (fMRI) technologies measure neuronal activity indirectly by tracking changes in blood flow and blood oxygen levels. Neurons communicate with each other by a process known as firing. In this process, they emit a slight electrical charge as an enzyme moves positively charged molecules — potassium and sodium ions — through the cell membrane. In the study, when researchers stimulated cell cultures of neurons to fire, they found that the exchanges of potassium and sodium ions were accompanied by an increase in the number of water molecules moving into and out of the cell.

Water movements only occur in the CNS/PNS via water channels that are made up of aquaporin 4 gates. This is going to become important later in the explanation of various diseases (MS). EVERY brain disease and EVERY autoimmune disease is tied to malfunctions in this mechanism

Remember that when water leaves a neuron, it carries a larger negative charge, and this charge induces an increase in the coherent domains in water networks inside the cytoplasm of the neuron. When the size of the coherent domains increases, it increases the optical efficiency within the neuron and outside the axon beneath the myelin where the interfacial water resides.

Remember that it is this interfacial water where Robert Becker found the regenerative DC current. This is why circadian biology and sleep are directly linked to regeneration. It all has to do with the scattering of light in water in neurons.

Ask yourself this: Is it biologically possible to predict the effects of lifetime exposure to electromagnetic, chemical, and physical agents that are not part of the biological experience of man given what we know about the butterfly effect?

If you do not fully understand light will you ever come to realize how important water is to life?

Evidence-based science has divorced itself from nature’s evidence.

Quantitative evidence-based science is used to remove uncertainty by transforming it into a probability for algorithms so that mathematical modeling can play the ritual role of haruspices. This epistemic governance arrangement in science is today in crisis.
The primacy of science today is to adjudicate political issues and it is having massive collateral butterfly effects on public health.
They must pass through an assessment of the level of maturity and effectiveness of the various disciplines deployed. The solution implies abandoning dreams of prediction, control, and optimization obtained by relying on a limited set of simplified narratives that linear thinking scientists and clinicians can understand to define the problem and moving instead to an open exploration of a broader set of plausible and relevant stories that define the real issues at hand.

CITES

Mae-Wan Ho, Fritz Albert Popp, Ulrich Warnke Bioelectrodynamics and biocommunication 1994, p. 21

https://medicalxpress.com/news/2023-01-good-hydration-linked-healthy-aging.html

https://medicalxpress.com/news/2019-03-younger-nightshift-workers-shown-pee.html

https://www.nature.com/articles/nature19756

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400257/

http://www.photonics.com/Article.aspx?AID=41237

Are assumptions the mother of all fuck ups?   Some will try to convince you that your assumptions are your windows to the world. They’ll tell you to scrub them off every once in a while, or the sunlight won’t come in to inform you of the truth.

Assumptions can be dangerous things for people to make, and like all dangerous things that are made — bombs, for instance, or strawberry shortcake — if you make even the smallest mistake you can find yourself in terrible trouble because of the consequences. Making assumptions simply means believing things are a certain way with little or no evidence that shows you are correct.  Moreover, if you just think about how assumptions affect thinking and decision-making, you might be able to see how this can lead to terrible problems. For instance, one morning you might wake up and make the assumption that your bed was in the same place that it always was, even though you would have no real evidence that this was so, that it had floated out to sea, and now you would be in terrible trouble all because of the incorrect assumption that you’d made. You might be able to see now that it is better not to make too many assumptions, particularly in the morning when the sunlight rises to inform you by uploading her wisdom.

On the other hand, assumptions can be useful.  Assumptions could be used as an artist’s palette of paint, and when we slept in that bed on a plane we’d use our beliefs to paint a new masterpiece as well on a freshly stretched canvas.  Your mind would act the role of the brush that pushes the paint around the canvas’s surface as you dream and assume what awaits you in the City of Lights.

Here, an assumption might look like this:  When you got out of your bed this time, you might discover that the bed was in a plane.  When you went to sleep you were flying over New York from Chicago on your way to Paris for the holidays just to be seduced by the lights, music, and atmosphere.  You wanted to dance the Tango on the Seine.  Below Point Neuf, you’d planned to meet a vivacious Frenchwoman who would invite you to a dark fire-lit jazz joint in Monmarte.  There you’d look into the eyes each other over a glass of Bordeaux.  Then, you’d get invited to her rooftop terrace where you’d gaze at the Eiffel Tower under starlight while resting your head on her beautiful shoulder.  Then, you’d wake up in white satin sheets and have breakfast in bed waiting for the sun to rise.  Then you’d walk hand in hand over to Point des Arts to hang up our lovelock.  But just then reality woke you in the bed of the plane over an ocean and you’d realize you never really appreciated what your job was really about.  You take people to places they dream of going by giving them a new chance to assume and choose.  Choices really are the hinges of destiny in life.  When you woke up and stepped out of that bed on the plane you’d realize you were traveling into a new world.  A superposition of what might be.  Here, one can be met by unfamiliar scents, where the colors of the rainbow take on a different filter, and where hearts can acquire a new beat.  You’d begin to realize you are so glad you are who you are, rational, calm, and so determined because the world needs people like you to get people like those reading this, to a place they have trouble imagining.

SUMMARY

Your perceptions influence all areas of life. The totality of your perceptions— regarding yourself, your life, life in general, and others, creates and impacts your personal reality and ultimately your experience of life.

Negative, disabling assumptions lead you in the direction of a very dismal reality. Positive, empowering assumptions give you every opportunity to live a rich, fulfilling life. Though assumptions don’t make your wishes come true, they can give you the perspective necessary for bringing your dreams to life.

Perception acts as a lens through which we view reality. Our perceptions influence how we focus on, process, remember, interpret, understand, synthesize, decide about, and act on reality. In doing so, our tendency is to assume that how we perceive reality is an accurate representation of what reality truly is.  Through perception, we become more aware of and can respond to our environment. We use perception in communication to identify how our loved ones may feel. We use perception in behavior to decide what we think about individuals and groups.

Perception is everything; the way you perceive things, the way you see things, is ultimately the way things will play out in your life.  Perspective helps us to understand situations from other positions and to consider other beliefs, experiences, and viewpoints. This gives us a better understanding and greater empathy. It reduces bias, and judgment, and reduces conflict.

The power of perspective is an intentional discipline. It takes time and commitment, but it creates an understanding between you and the people you lead that allows you to move forward, faster—and with increasing success.

Your perceptions need to be sharpened in 2023.  Realize you need to describe your relationship with truth and false perception this year.  You cannot rely on experts or the media.  You need to deal with your own and other’s perceptions.

“Perception is more important than reality. If someone perceives something to be true, it is more important than if it is in fact true. This doesn’t mean you should be duplicitous or deceitful, but don’t go out of your way to correct a false assumption if it plays to your advantage.” 

In 2023 you must obtain clarity in declaring the acceptability of what is false.

The annual tradition continues.  Here is my wish list for my tribe in 2023.

“Nothing is more powerful than an idea whose time has come.”        -Victor Hugo

2023 should be the year you optimize yourself over everyone else.

I expect massive storm clouds to appear in 2023.  Face into this storm.

There are 2 types of people in the world.  Those who make things happen and those who asked what just happened?  Which type are you at the end of 2022?

To overcome anything in life you must get off the “What happened” page to the “make it happen” page.  Circumstances are the rulers of the weak, but they are the tools of the wise.  The happiest people are not those who have no problems but are those who have encountered difficulties and even tragedies and have overcome them.  A challenge only becomes an obstacle when you bow to it.   Today begin to realize how many great things could happen to you by simply confronting the things that scare you most.

Before the year closes begin to forgive those who wronged you in 2022.  Stop keeping score.  Harboring grudges is poison to our body, mind, and soul. Today, deal with it and remove it. Begin to forgive quickly and freely with no conditions attached.  When we choose to forgive, we gain personal freedom in how we think.  Once you forget what you are worth, you forget what you deserve….

However difficult we may find it to let go, there is never a wrong time to do the right thing. Remember as humans we are designed to face the very same defects and failings as others do.  This reality allows us to keep things in their proper perspective.  When you are able to forgive, you get back into alignment with your purpose and plan and are able to share your talents with the world.

Every person needs to take one day away to sharpen the blade.  To go out with the setting sun on an empty beach is to truly embrace your solitude. A beach is not only a sweep of sand but shells of sea creatures, sea glass, seaweed, and the incongruous objects washed up by the ocean. A simple life is good for me. I don’t need a whole lot to rest there.

Today, become the shaft of lightning or the glowing candle that illuminates your world. Be fast, furious, bold, and strong. Arrive quickly and depart just as fast, leaving behind a brighter mind or soul, or heart in all you touch. Your gifts lie not in what change brings to you, but rather in casting light on what you can bring to the world. In your work be legendary; in your life make history.

Life is a show. It’s up to you how to make your own story, do your own show and how to live the show you are on. You choose who you need to meet, where you should have your scenes, or which scenes you want to do. How awesome your mind can do right?  Get to it now…….create your own story for 2023.

The steps for you to consider for 2023

Managing your emotions isn’t the same as suppressing them. Ignoring your sadness or pretending you don’t feel pain won’t make those emotions go away.

In fact, unaddressed emotional wounds are likely to get worse over time. Embrace the suck of bad emotions so you can climb the mountain of positive ones in the future.  That will be important this year because I expect financial hardships to spike in 2023. And there’s a good chance suppressing your feelings will cause you to turn to unhealthy coping skills–like food or alcohol.

It’s important to acknowledge your feelings while also recognizing that your emotions don’t have to control you. If you wake up on the wrong side of the bed, you can take control of your mood and turn your day around. If you are angry, you can choose to calm yourself down.

Individuals who believe their talents can be developed through hard work, good strategies, and input from others have a growth mindset. They tend to achieve more than those with a more fixed mindset those who believe their talents are innate gifts. This is because they worry less about looking smart and put more energy into learning.  Embrace this mindset in 2023.

Writing helps build your self- awareness.  Consider beginning a journal in 2023.

Writing daily will help improve your self-awareness practice by providing you with a written record of your thoughts, so you can reflect on them more easily than relying on your memory alone. As you write, you’ll begin to see what’s holding you back from making the change you want to make in your life.

How do you see the present moment?  I’m expecting a bad financial year in 2023, but when we get to October of 2023 I’m expecting a massive upturn in things because the early failures of 2023 will lead to a rebirth in late 2023.  Is your current perception reality? Only a quiet mind perceives the world”s reality. Sometimes our perception is not reality because we look through the eyes of hurt, pain, anger, envy, the unseen. We are enslaved by anything we do not consciously see. But we are freed by our conscious perception. What we all have to learn is, that we’re responsible for our perception of things. As we gain wisdom, we see the magic in things because our senses grow sharper. Reality is that which, when we stop believing in it, doesn’t go away.

We all go through daily evolution of ourselves and each other. It is what guides us to do the best we can do, especially when it really matters. However, it can also derail us from meeting our ultimate potential and goals when we try to do too much with such little time. When this happens, it deflates our self-worth and erodes our confidence in ourselves. And if we are not focused on the big stuff, we are not meeting our greatest potential.  Change that in 2023.

Embrace the suck of change.  People struggle with change because they have a hard time imagining a world that doesn’t yet exist.  They wait until the change becomes obvious to adapt.  People who do that fade to black.  Avoid this in 2023

Not only does listening enhance your ability to understand better and make you a better communicator, it also makes the experience of speaking to you more enjoyable to other people.  Listening connects us to others and connectedness has been shown to be the key to human happiness. Our human connections and relationships matter far more to us and our wellbeing than money, or fame, or material possessions. We urgently need to reclaim the art of listening.  Enhance this in 2023.

There is a difference between putting an idea away versus giving up.

Call it semantics, but there is a fundamental difference between “quitting” something in a fit of frustration, and taking an idea to the end of its path and then deciding, calmly and with a clear head, that it’s time to move on to something else.

When you “give up,” you continue to carry that baggage with you long into the future. You still think about it. You wonder. You may even feel regret.

That’s very different than fighting as long as you can for an idea and then realizing its time to pivot, or shift, or move on all together.  Right now many people who bought Bitcoin in 2020-21 think they made a mistake at the break of 2023.  The picture tells you where I think we are with respect to Bitcoin and why I very bullish for October 2023.

Have a happy New Year !

We’re going to try something new here..  I’m going to post one thing that I’m passionate about, that drives me, and that I love.  Please do the same on the forum or in the Private Facebook Groups.

I’ll start.  For me figuring out how nature works to use light to build all the things we observe and experience drives me.

The most amazing thing light has built is my nurse at KLC.

She is my best friend and now she provides the air I breathe in my lungs.  It astounds me that as light slowed down here on Earth by crashing into some atoms in a specific way that a creature like her could be created.  She is not only the best nurse I have ever worked with but I have fallen in love with her.  It turns out we’ve been entangled for a long time below our ability to realize it.

I had always thought I’d always been broken by love and dark inside. Then I realized it was through those cracks that the light gets in.  She shines that light.

You know you’re found amazing love when you can’t fall asleep next to her because your own reality with her is finally better than anything ever found in your dreams before. And in the memories of those dreams, you recollect desires just to be the atoms of air that enter her quietly, while it sustains her for just that moment as you look at her sleep. This fuel becomes the air that nourishes you.  The key is you become aware of this quantum connection slowly over time and do something about it.

For a long time, my goal was to remain invisible to her so she could maintain her free will, but simultaneously I found it necessary to remain in distant contact with her.  This mimicked “spooky action at a distance.”  Love is the essence of quantum entanglement.  Teaching people about entanglement is also a labor of love.  Quantum entanglement is the biggest part of love and all of its connections.

She was ignorant for decades that she exceeded my imagination.  She alleviated much of my professional stress early on in residency by knowing what needed to be done before I ever asked her to complete a task in the operating room. She taught me insidiously that I should embrace the chaos of my job and make it an enjoyable lesson to be used as fuel.  I became oblivious to the professional discomforts of this lesson to get the job done efficiently.  No neurosurgeon taught me this.  She did.  I never properly thanked her back then.  I had to come back years after my residency was done one Christmas to thank her.  When I did,  quantum entanglement hit me square between the eyes.  Entanglement is all about companionship really. Self-companionship to be more precise. It’s simply not good for one to be alone.  I began to understand its implications for life.

Entanglement means some aspect of our description of behavior that can’t be separated by space, time, or dimensions. We might describe this as a fractal nesting of scale.

I felt her absence over great distances and times. It was like waking up one day with no teeth in your mouth. You wouldn’t need to look in a mirror to know they were missing

I define quantum entanglement as the energy source that exists between people when they feel seen, heard, and valued; when they can give and receive without judgment; and when they derive sustenance and strength from the relationship. It is as if a pair of entangled humans are like islands in a vast ocean, separate on the surface but connected by landmasses in the deep.

On December 28, 2018, I decided to find out if she really loved me, I hooked her up to a lie detector. And just as I suspected, my machine was broken.

Every one of her abilities came from starlight.  Her brain refined the light to enter the broken pieces in her neighborhood.  Christmas is also a story about starlight.  Many people sing about the “Star of Wonder” that guided the wise men to a manger in the little town of Bethlehem, where Jesus was born. They’re commemorating the Star of Bethlehem described by Matthew in the New Testament.

Sunlight, water, and magnetism made a remedy for me.  That struggle has been a long one.

I needed to understand entanglement fully before my own “pilot light” goes out on this pale blue dot.  Today. I wanted to share it with my tribe.  My Christmas gift to you is a thought:  we should not and cannot live just for ourselves. A myriad of energy fibers connects us with our fellow man. Sometimes people who are fully entangled never realize who they were meant to bond with.  That was my story for a long long time.  We do not find the meaning of life by ourselves alone – we find it with people with who we are entangled.

Light organizes matter in the entire cosmos but the type of light, the spectrum of this light from a source, has its own unique ability to sculpt atoms in specific ways to create new things from its inherent organizing ability.  It is this ability hidden deep within the spectrum of light but that is the key to understanding life and love.  It provides change without the perception of change.  The thing that shows up every morning in the eastern sky, which is most familiar, remains the most mysterious force in the Universe.  That force organized every life system and every feeling of love that has ever existed. Matter exists to make love to light, to separate its electric and magnetic fields in ways that we just do not understand, and from this dance, light can sculpt a life, make a child, and create a new species.  Everything man has known comes from the mysterious moves of our star’s light as it fell to this wet rocky planet.  It is sheer amazement to me.

What have I learned about quantum entanglement and love?

There is no perfection in love, only beautiful versions of brokenness.

Some of us scream about everything that has gone wrong in our life. Stop it.  It makes no difference. We should scream at ourselves for everything broken in our lives.  Light has a lesson for the broken.  You are damaged and broken and unhinged. But so are shooting stars and comets.

Sometimes, reaching out and taking someone’s hand is the beginning of a journey.

At other times, it is allowing another person to who you are connected to take yours and lead you.

Living systems are nests of atoms of carbon, hydrogen, oxygen, and nitrogen, together with traces of a few other elements, yet of a complexity of structure that has hitherto resisted all attempts at complete analysis because we do not understand how light and water bind and weave the process of atoms in things.  This makes our protoplasm the most enduring and the most easily destroyed of substances we know; its molecules are constantly programmed electronically by light to break down constantly, yet reorganize under solar power to furnish the power for the manifestations of many vital phenomena.  Yet, through its remarkable property of assimilation of light, a power possessed by few other things on earth, it constantly builds up its substance anew from the surrounding medium and it avoids our perception of its recipe.

Here is my tribe in El Salvador embracing light, water, and magnetism.  Let’s hear about what you are passionate about below.

Podcast

The link above is not a regular podcast.  It does the job of explaining how life does some of the things it does.  There is a “revolution on the surface of the earth” called technology, and it is causing a new evolution of free radical signals in your mitochondria causing diseases.  The result of these collisions with your semiconductive proteins creates your “health reality”. Your health manifests from these collisions and creations.  How this happens is the subject of this blog.

Let’s use an example from human metabolism for a thought experiment: it is established that all so-called “chemical reactions” are merely the movement/expression of electrons/energy. Matter, the nucleus of the atom, the “nutrient” is inert in chemistry and biochemistry.  At least that is the current belief of the biological paradigm.  I showed in my Vermont 2018 talk this is also false.  This can also be found on Patreon.  It is believed by the great majority in science only the electrons of atoms are dynamic, capable of change, force, and movement. This is also not true.  Protons move with the help of red light from the sun and the hydrogen heat furnaces of our mitochondrial colony. That is the first law we will call on to verify our thought experiment. Secondly, we call on this: it has been established that electrons gather/collect and only interact with photons.  This is the basis of the photoelectric effect and is further understood as a cell’s Jablonski diagram.  Electrons are excited by sunlight and fall back to the ground state.  This process is capable of increasing their energy and delivering information to the system by changing the spin state of electrons, protons, and photons trapped by the organelles of a cell.

It turns out, electrons emit/yield photons to the demand of the body when the electron moves to another atom or molecule when it falls to the ground state.  That light captured by electrons drives many processes in our cells.  Electrons are more or less reactionary to the power density in the UV spectrum and use this information buried in wavelengths of UV photons.  All cells emit ultraweak extreme UV light as a consequence of metabolism. This is a key feature of life’s design discussed in the book below.  You should add it to your Christmas shopping lists.

This is the only part of the visible spectrum that is capable of using non-linear optics. Having established these two irrefutable principles, one must conclude: when there is a deficiency of some sort of enzyme, chemical, or substrate in a cell there is a resultant physical reactionary change inside the cell.  That change might be in a hormonal or enzymatic or functional aspect of the tissue in question.  It could even be left in the hydrogen bonding network of water around the semiconductive proteins inside a cell.

Resonant Recognition Model (RRM), proposes that protein activation inside of cells is electromagnetic in nature within the frequency range of infrared and visible light.  Irene Cosic has written extensively about it.   The RRM postulates that protein interactions entail a mechanism of resonant energy transfer between involved molecules at the frequency specific for each observed function/interaction inside a cell. This theory is based on the findings that certain periodicities within the distribution of energy of delocalized electrons along a protein molecule are critical for protein biological function and/or interaction with their targets.  Free radicals delocalized electrons inside of our cells. If charge transfer through these macromolecules is introduced via ambient light, then charge moving through macromolecular backbone can produce electromagnetic radiation, absorption and resonance with spectral characteristics corresponding to the energy distribution in light that activates things in cells.  This means light is fully capable of replacing damaged or non functional proteins in cells to restore function.  Irene has showed this with lactate dehydrogenase and  UDP proteins in Crigler-Najjar syndrome.  

She found that IR-A light could replace missing lactate dehydrogenase to restore physiologic function.  In Crigler-Najjar Syndrome, which is a severe form of Gilbert’s Syndrome, she found that replacement of blue light frequencies in young children was able to help them clear bilirubin and lower jaundice associated with this condition without any use of Big Pharma solutions.

Water at an interface, in a cell, or in the atmosphere (pictured above) has a surface tension due to the polar interactions of water with other water molecules at the interface surface of these semiconductive proteins and lipids. This clustering of coherent domain imparts a crystalline like property to the water. In the bodies of living organisms, the clusters form hydration layers around biological molecules. It is known from electronics that different patterns which contain information result within an cluster depending upon its atomic structure.  Free radicals rearrange the electronic structure inside of cells. Thus, depending on its structure, each molecule has an oscillatory pattern (resonance frequency = Resonant Recognition Model) that can be determined by spectroscopy.  We can now see the effect of free radicals on cells using spectroscopy.

It is well known, through spectrographic analysis, that water and other dipole molecules are able to be entrained to exogenous oscillatory patterns by rearranging their cluster patterns. Light and free radicals are capable of doing this. The cluster rearrangements then resonate with the entraining frequency of light.  Sunlight creates electric fields that not only allow electrons to delocalize, but sunlight can free up hydrogen protons to move.  When they move they activate the semiconductive molecules in cells to action or inaction.

Taking an exogenous substrate will never repair the deficits of having excited electrons creating these substrates.  The reason is simple.  Feedback loops use the substrates they create as their interactive controller of the cycle.  Loss of this control causes the cycle to uncouple and heat is thermalized to the local environment and quantum coherence is lost as water loses its coherent domains.  As coherence is lost in cell water, redox power drops exponentially.  There are physical manifestations of this in the matrix of size and shape change of the mitochondria, along with spacing out of the cytochrome proteins that tunnel electrons from food.

This can occur in a muscle or any organ within the organism.  The skeptic will need to admit, the specific deficiency in this system of control is due to a lack or loss of photonic power within this quantum system.  If one adds and moves electrons and protons properly,  light frequencies within the visible spectrum are capable of creating the matter a cell factory needs to operate.  That is what free radicals are doing in mitochondria.  They are sculpting the life we experience.  Free radical signaling is critical in creating the right amount and programming melatonin made in your mitochondria.

Free radicals are foremen in our “cellular refinery” that tell other worker proteins how to act.  Light is the instruction manual for the creation of free radicals.  No one needs any supplement when you understand how a cell operates by arranging atoms using the levers that light, water, and magnetism provide.  To create matter a cell needs cell must have redox power to do it.  The optimal redox power is -400mV.  Most humans live between -200mV—400mV.  Improving that redox number is the key to regaining your health.

SUMMARY

The beliefs of modern man around the light he has created have become the batteries that make them fuel for the matrix in which they live.  Few realize how toxic that fuel really is for them.  It is in the pauses, the intervals, and the spaces between the words, that the meaning of what you are saying that sinks in. To listen to a good talk, whether from a pulpit or a podium, whether off-the-cuff or seared into memory, is to hear a kind of music, not just in the register, the lilt, the cadence, and the rhythm, but in those moments when there are no words to be heard when all you can hear is the enveloping silence.  It is like being in a sensory deprivation tank when you are trying to regain your health.  The same is true with cells; sounds are like sunlight and silence is found in the darkness of night. The real music of life is found at night when light SHOULD ALWAYS BE absent. This is why ALAN, called artificial light at night, is so dangerous to humans.

ALAN destroys many of the free radical signals in you and leads to mitochondrial diseases that are the basis of ALL modern disease epidemics.

The modern disease epidemics began after 1879 when the light bulb was discovered.  A few years later in 1893 Tesla gave the world the AC power grid.  This gave man the AC electric power to destroy himself with his own innovation because that grid became capable of creating man-made light that ruined how sunlight creates the binary code of life in our free radical signaling.

I am here to tell you that our modern disease epidemics all come from the electromagnetic environment we’ve helped build and sustain with our choices around light.  It turns out, these seemingly innocuous things change the free radical signals a mitochondrion can generate from the oxygen unused in metabolism and incident light we live under.  These two stimuli allow us to change the binary code of quantum spin states in subatomic particles in our bodies.

The visible spectrum of light from our sun lowers the sensory inputs to mitochondria to decrease power consumption in the defective colony of mitochondria.  UVA and UVB light in sunlight normally slow electron chain current, while the IR-A light allows the ATPase to spin faster to make ATP while limiting oxygen consumption to control the free radical creation in mitochondria.  Light controls how much leftover oxygen is in a cell and that level of oxygen is the substrate of what generates the free radical signal

No one sees this perspective because they do not understand energy production in mitochondria and how it uses electron, proton, and photon spin numbers to make matter from light. The incident EMF a mitochondria sense inside cells is the key to understanding the mysteries around all our disease epidemics.  This picture below should stun you.  A lack of sun is the biggest risk to human longevity.  The sun is the best medicine a Black swan mitochondriac will ever receive this holiday season.

Based on Cosic’s work she has used RRM  to analyze the spectrum of many proteins with biological functions/interactions in humans.  Shockingly, she has found and reported that proteins SPECIFICALLY only use the spectrum of terrestrial sunlight on the Earth.  This should make sense to you because the source of all energy supporting life is sun light.  All life is sustained by the sun light.  Cell water is transparent to RRM frequencies, and this enables proteins and DNA to interact without any loss of energy from solar photons.

The spectrum of artificial sources of light, as opposed to the sun light, do not cover the whole RRM spectrum used by biomolecules and this explains why decentralized MDs have concerns that man made light leads to disease propagation by causing disturbances in many of the biological functions of proteins/lipids and consequently, influence the health of man.  This picture below shows you the spectrum of light is not homogeneous.  Since it is not homogeneous, light changes how life acts.

CITES

Cosic I. Macromolecular Bioactivity: Is it Resonant Interaction between Macromolecules?-Theory and Applications. IEEE Trans Biomed Eng. 1994;41:1101–14.

Cosic I. The Resonant Recognition Model of Macromolecular Bioactivity: Theory and Applications. Basel: Birkhauser Verlag; 1997.

Cosic I. Virtual spectroscopy for fun and profit. Biotechnology. 1995;13:236–8

Cosic I, Cosic D, Lazar K: Is it possible to predict electromagnetic resonances in proteins, DNA and RNA? Nonlinear Biomed Phys. 2015; 3

Cosic I, Cosic D, Lazar K. Environmental Light and Its Relationship with Electromagnetic Resonances of Biomolecular Interactions, as Predicted by the Resonant Recognition Model. Int J Environ Res Public Health. 2016;13(7):647

If you want lasting change in your health, you have to give up the idea of just trying something.  Nature never rewards us with health if we dip our toe in or just peek through the glass at her light.  Every AM you must commit to being all in.  When you put all the chips in you’re telling yourself you don’t want to be ordinary.  You are willing to put the extra in to become ‘extra-ordinary’.  That is what mastery requires.  If an A is available you take it.  You never settle for a B, C, or D by dabbling or procrastinating. Black Swan mitochondriacs have one method and it is about fully immersing yourself in nature. Mitochondriacs know that no life is controlled by what you do some of the time, it is defined by what you do consistently every AM when the sun rises.

In all of the major model organisms in which circadian rhythms have been studied there has emerged a central organizing principle of molecular clockwork: within cells, a set of clock genes and their protein products together participate in autoregulatory coupled feedback loops of transcription and translation to produce an oscillation with a period of about 24 hr.  This links light to protein degradation and nucleic acids are what make protein in us. All of these biological substrates sit in coherent water to operate as designed.  This is why light activates ubiquitination rates and ubiquitination couples to epigenetic expression. It also points out why food is not the “key player” we are taught.

Most people know that the suprachiasmatic nucleus (SCN) in the brain is where the circadian pacemaker lies in humans. It monitors this dance between darkness and light, and the seasonal cold and hot temperatures in our environment to help control and monitor our own growth and development. Evolution apparently agreed to use these signals in all living things because this is what it uses for all life on earth today.  Optical photonics opens another trap door for centralized medicine to be aware of. The polarization of light has massive effects on hydrated protein thermodynamics. Sunlight is unpolarized.  When sunlight is absorbed and trapped by biological systems that light becomes polarized by the organic substrates in cells.  I will discuss that process below.

With respect to the polarization of light, hydrated proteins are like an oil refinery.  Oil refineries take a barrel of oil and make products from it to help “industries” do things.  Proteins inside of a cell do the same thing to light.  They refine light to create things a cell needs.  Atomic arrangements in proteins change their electronic status. A change in the electronic status is a change in its charge density.

You can see every atom in a protein has a different electronic structure due to what the atom is bound to.  Therefore, it is important for you to understand that the charge density in any molecule in any cell is not homogenous.  In the SCN, this nucleus acquires more homogeneity than most other places in the brain because of how coherent domains in water in the retina are transmitted back to the SCN.    When light strikes proteins in the SCN, it alters the charge density of atoms in the proteins of the clock mechanism further. Implications for circadian timing are even bigger.  Why?

The varying electric charge tells us that each atom in the base ring of the aromatic molecules experiences time differently when light radiation interacts with its atoms.  When coherent water surrounds those rings, they begin to act in unison and take up a pacemaker role.  This is how cells begin to oscillate in the SCN neurons.

Time is always relative in the universe unless the atomic arrangement of hydrated atoms is aligned to take advantage of quantum field effects.  The SCN was built by Nature to be an optical lattice clock. The coherent domains (CD) of liquid water in the SCN are susceptible to giving rise to a large number of excited states in the presence of light or electromagnetic waves.  Given the plurality of the exciting levels of the molecules in the CD of water, it becomes able to withdraw small amounts of energy from the sun, transforming them into coherent vortices of quasi-free electrons inside of the SCN.  The same thing happens inside the CSF cavities of the ventricular system of the brain.  I spoke about vortices of water in the hyperlink you just passed.

The duration of these vortical excitations can be very long (days, weeks, months) since internal friction is zero within the CD system.  This occurs because of the action of coherence.  Without friction, there are no collisions and the CD can not dissipate energy in a thermal form. Given the long duration of these excitations, it is possible to accumulate many of them within the domain of the SCN to operate in unison. Each vortex is a motion of electrons = electrically charged particles = gives rise to a magnetic moment = the appearance of a magnetic moment = makes the coherent domain turn and align in resonance with the magnetic field of Earth = this magnetic field then can entrain all the mitochondria of the SCN to operate in unison by magnetic resonance.  This is how your eye clock resonates and connects wirelessly to the internal heartbeat of Earth.  The video above shows this process.

The suprachiasmatic nucleus (SCN) is the master circadian clock of mammals, is composed of multiple circadian oscillator neurons which create coherent water.  They affect the firing of many other neurons in the hypothalamus as the picture below shows.  Most of these neurons exhibit significant circadian rhythms in their clock gene expression and spontaneous firing when cultured in dispersed cells, as well as in an organotypic slice.

In quantum mechanics a coherent state is the specific quantum state of the quantum harmonic oscillator, often described as a state where a group of atoms has dynamics that most closely resemble the oscillatory behavior of a classical harmonic oscillator.

Coherent water is made inside mitochondria because it excludes deuterium.  Coherence is more difficult to achieve as atomic mass is raised.  Because coherent water is excited water with a plasma of almost free electrons, it can easily transfer electrons to molecules on its surface to the clock proteins of the SCN. The interface between fully coherent interfacial water and normal bulk water (in the circulatory system) becomes a “redox pile” of stored energy.  All biological envelopes, from cell membrane to epithelial tissue, contain this aqueous phase in a liquid-crystalline state or are perfused by it. It is water in a particular phase of the quantum organization (oscillatory coherence) that is close to charged hydrophilic surfaces and is confined in layers of the coherent domains.

It has a high capacity to:

1. retain electronic charges, in the form of vortical excitations of quasi-free electrons, storable as energy reserve

2. induce an electronic and protonic long-range and long-life excitation of the different molecular species available, enabling their selective activation and mutual attraction

3. convert mechanical vibrations created when light hits proteins (phonons created by quanta of electromagnetic energy = photons) and vice versa undergo a piezoelectric effect

4. Molecules in tissues like the SCN obtain their shape in time, not in the space they inhabit alone because of the light they absorb. Some protein polymers have human potential within them embedded in their future.  What determines this is the sunlight that interacts with these proteins to shape them in time. The frequency signal in sunlight creates biological truth cells need to function. The frequency noise in man’s light is what distracts cells from their biological potential.  Man made light creates lies, and these are lies in timing. This affects how the eye clock measures time.  If you say don’t have time to do things correctly, what makes you think you’ll have time to do it over?  Nature usually does not give do overs.

THE WATER IN THE EYE CLOCK

Water is a dipole.  It has a positive and negative pole.  Like other dipoles, water molecules can stack together in dipole interactions with the proteins of the SCN clock mechanism with alternating positive and negative poles next to each other. It can also engage in electrostatic interactions with charged ions and other dipoles dissolved in it. Most importantly, it is primarily the charge distribution on the surface of molecules that determines their physical and chemical properties.  That topology is critical when you are building a clock like the SCN.

Inside the SCN the interaction of the clock gene proteins and water is affected by bonding ability, atomic orientation, and mutual position inside the cell.  How do things in the SCN begin to work in unison?

The separation of positive and negative charges in biological water is important for short and long-range collective coherent correlation (SLRCCC), especially in proton-SLRCCC.  Proton movements in water are critical in SCN function.  Modern biologists still are ignorant of these facts.

Neither classical nor standard quantum theory predicts quantum coherence for water, largely because they ignore quantum fluctuations and the interaction between matter and the vacuum electromagnetic field (VEMF), which are taken into account in Quantum Field Theory (QFT).  QFT has yet to be fully accepted anywhere in molecular biology and this is why the patients of modern medicine continue to suffer from diseases they do not have to.  Our knowledge of what nature is doing in our cells is the key to future healthcare success.

When the geometrical configuration of two molecules fits in such a way that a minimum of the (electrical) Coulomb potentials of the valence electrons is achieved, chemical bonding can take place.

However, charge distribution through its time variations is also responsible for the properties of the electromagnetic radiation that molecules emit after their interaction with light.  This is what polarization is. Polarization is affected by the atomic spatial distribution of atoms and their electrons.  Their direction is also critical in their interaction with the impinging radiation coming from the retina toward the SCN.

The key point to understand about the SCN is that the interaction of light radiation with matter is only possible through the redistribution of charge density = dielectric constant of water 

QFT and QED however allow for other interactions that are operational in biological water. How do we know this?  Pure bulk liquid water consists in two interspersed phases, coherent and incoherent domains that have widely different dielectric constants.  Coherent water has a high dielectric constant of 160 and incoherent water’s dielectric constant is 15.  A high dielectric constant means water becomes highly polarized in this state.  The high polarizability of the coherently aligned water molecules tells us that they are oscillating in concert.  We can see this effect on a polarized microscope. This is how the SCN works.

For evolution to work optimally, a cell first must adapt to its environment.  The first situation any living cell would be subjected to in an earth day is a period of day and night. Over time it would also be subject to the seasons in our environment because of the earth’s revolution, tilt, and angulations of the sun. The environment motions of light, water, and gravity was coupled by molecular resonance to the PER 1 and PER 2 genes and to Bmal1.

As time continued on, further life would have been subjected to solar variations and would have had to account for it. When it was night time, the interior of cells became more reduced chemically and electrically. NADPH (nitrogen) would have to be replenished within the cell while the DC current within the cell at daytime would have to diminish during night time.  This would result in a good redox potential within the cell to drive life forward.

During night there was absence of light, resulting in  a different redox state compared to the oxidation of the sun’s light.  When light was absent, cells would be optimized by developing recycling programs, for their components using autophagy during sleep.  Orexins added to the SCN function as evolution progressed. During the day while energy is being expended to explore the environment,  the cell would become more oxidized  because it was losing electrons and energy to its environment.

This loss of energy could be harnessed by mitochondria to signal.  Some oxygen was diverted from metabolism to create free radicals to signal. The loss of energy resulted in a superoxide burst = free radical burst.  If it was sustained H2O2 was made.  Two enzymes were innovated to control this process in mitochondria to signal autophagy and apoptosis.  If energy loss was exceeded the hydroxyl free radical was made.  There is no enzyme to scavenge this free radical.  Only molecular hydrogen gas can do his job.  The microbiome makes 8-12 liters of H2 normally when it is healthy.  If more hydroxyl free radical is made, then the system can’t buffer itself, disease generation and eventual aging is the result within that tissue. Why?  Timing is off between the SCN and gut molecular clocks. The SCN neurons have to run faster than the organ clocks because of the laws of physics.

Cells had to find a way to transform energy before food was created by photosynthesis around 700 million yeas ago.  Food as we know it today wasn’t on Earth for the first 3.5 billion years of our planets life. Primative cells used water and light to survive.  Cells used water as an electromagnetic battery to power itself.  Water is a natural  repository for electromagnetic radiation, and as such naturally absorbs light waves from our environment.  Water becomes an ideal battery with infrared light. Our skin and plasma became a solar battery for both UVB and IR light.

SUMMARY

Blue light causes the SCN to lose its oscillatory patterns and this leads to disease.  This begins with melanopsin and orexing dysfunction in the retina.  Think about how blue light causes diabetes or prion disease.  

The non-visual effects of blue LED light on hormonal systems containing melatonin, cortisol, glucose, insulin provide an endocrine understanding of how it happens. The elevation of cortisol by blue light leads to the increase of the glucose level in the blood and the stimulation of the production of insulin in beta cells.  This mimics what excessive food intake does.  It gives rise to irreversible decline in the number of insulin receptors on the cell surface, and thus–to a steady reduction in the ability of cells to utilize glucose, and devolves into type 2 diabetes.

Melanopsin defects in the skin and retina ALWAYS predate leptin resistance in man’s chronic diseases. Leptin resistance trumps defects in cortisol in the human cascade in the brain and body because melanopsin dysfunction destroys melatonin before cortisol cycles are RUINED. This leads to a cascading effect in the brain once it occurs in the retina.  

Cortisol is a slow acting hormone and melatonin is rapidly active hormone because it is created and acts on the colony of mitochondria in humans. So anytime cellular stress is high (light stress or high High Sensitivity CRP), it also forces all the hormone backbone substrate called pregnenolone to be shunted to cortisol production. This is called pregnenolone steal syndrome. What exactly does this mean? All of the hormones made from a common precursor — DHEA, Androstenedione, Vitamin D, testosterone, estrogen, and aldosterone production — fall dramatically as a result.

Remember that chronic leptin resistance in the hypothalamus leads to huge hypercortisolism all the time!  When cortisol is raised you know as a clinician that melatonin levels are destroyed because of this resonance effect.   This also means that leptin resistance clinically will lead to low vitamin D levels, which in turn, down-regulates T-regulatory cells of the immune system (infection risk up), and it will decrease bone metabolism (osteoporosis) as well since vitamin D3 metabolites (1000 of them) are cofactors in bone metabolism.

When cortisol is up melatonin is down and this predicts the loss of the oscillatory pattern in the central retinal pathways.

When there is a loss of oscillatory patterns in the SCN, the brain becomes more susceptible to prion diseases because of this CNS stress response. This has also been proven in prion diseases, and Stanley Prusiner’s got a Noble Prize for it. An LCHF guru made fun of Dr. Prusiner’s work and called it pseudoscience before it was given a Nobel Prize (Gary Taubes).

The prion mechanism, implies that circadian mismatches of light can alter the polarization of light in our tissues, which results in altered cellular signals.  The proof that this process can occur in us, is easy to resolve because we now can see size, shape, and location changes of proteins, organelles, and nucleic acids that are suspended within the water of our cells with electron microscopes.  This is no longer “a best guess theory”. This can be done with tissue samples, neutron scattering studies, or an MRI.

Today is the day that you should start to take control, to be proactive, to reach out to others, to help them initiate change in some fashion. The greatest good you can do for another is not just to share your wisdom riches but to reveal to them their own.

Mankind has not woven the web of life. We are but one thread within it. Whatever we do to the web, we do to ourselves. All things are bound together. All things connect in ways few understand.

We attract wisdom we are prepared to receive. People in medicine and ancestral health care more about beliefs than reality or truth because they create their own versions of reality they use in their businesses.  Everyone needs to become aware of the biological cost of bad thinking.  Every single eutherian mammalian gene has a clock gene in front of their somatic genes.  Ask yourself why that relationship exists.  Is it food or light that controls your biology?  Circadian rhythms are controlled by hydrated “clock genes” that are entrained by light.  The water they sit in is coherent. These are facts, not my opinion.  Be careful whose beliefs control your ability to think. If you’re smart your template will begin with the sun and not with food. Think for yourself.

People who lack the clarity, courage, or determination to follow their own dreams will often find ways to discourage yours. When you change for the better, the people around you will be inspired to change also….but only after doing their best to make you stop. Live your truth and don’t EVER stop. …

CITES

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664573/

https://pubmed.ncbi.nlm.nih.gov/26625615/

https://www.cell.com/action/showPdf

https://scitechdaily.com/quantum-destabilization-of-a-water-sandwich-laws-of-classical-physics-break-down/

Who motivated you to be better in 2022?

Have you told them yet?  If not, why not?

Stop right now and call them up and tell them what they did for you.

It is a scientific fact that gratitude reciprocates

Gratitude makes us confident. Confidence makes us passionate. Passion fuels the journey. When life seems complicated, sometimes all you need is a different vantage point to look at things differently.

Do you look to people who think in terms of evolutions, not revolutions?? Is failure a key to your experience?? In 2022 my best friend motivated me to be better than I ever have been because she told me to stop sacrificing my time for things in my life that were not worth the expense.  She motivated me to walk away from several things I was doing to waste time.

She made me realize that our choices can allow us to take our life into our own hands, and control what happens.  She made me realize if you cannot bet on yourself you need to get out of the business of teaching.  If you are not good enough for yourself don’t bother teaching others.  If you’re not a risk taker for our health, you should close up shop and head to Vegas and let the casino odds determine your fate.  That reality woke me up.  You need truth tellers in your circle of six.  If you don’t know what you want, you’ll never find it.

If you don’t know what you deserve, you’ll always settle for less than you deserve.

You will wander aimlessly, uncomfortably numb in your comfort zone, wondering how life has ended up here.  Embrace the discomfort of a friend who tells you the truth no matter how hard it is to take.  The biggest human temptation is to settle for too little.  Blame doesn’t empower you. It keeps you stuck in a place you don’t want to be because you don’t want to make the temporary, but a painful decision, to be responsible for the outcome of your own life’s happiness.

Change that in 2023.

Drop me a comment on who motivated you in 2022.

PS:  Also a small shout-out to Elon Musk.  Musk is an entrepreneur and not someone I look up too since he favors cars that use electric power.  He does not need a job or money. He beat BIG BANKS with PAYPAL 25 years ago. He beat DETROIT with TESLA when he refused to play by their playbook. He beat NASA with SpaceX by removing layers of bureaucracy.  And he will beat COMMUNIST censorship with TWITTER by firing their activist board. Thank you and GOD bless ELON MUSK for realizing that the first amendment was worth a 44 billion-dollar gamble in 2022.

It’s called the First Amendment. The people that swore to uphold the Constitution violated their oath. It is time for accountability.

The government had a private business remove accounts from their social media platform sounds like something that would happen in China but it didn’t. It happened in America.

Just to be clear:

Candidate Biden lied

The media lied

The FBI lied

Intelligence agency “experts” lied

Tech firms lied

And they all knew they were lying, to try and interfere with the 2020 election

That is a December 2022 reality.

Once you awaken you cannot come back to what you were before.  History is what sticks around and continues to bother us to action.

CITES

https://twitter.com/lib_trigger/status/1598887961554464768

https://twitter.com/erichhartmann/status/1599045606701289472

Your worldview has to be structured in principle on some specific doctrine that shapes how you function and view humanity. Embracing QED is akin to wearing steel-toed boots in a ballet-slipper world. Understanding that life is bigger than your set of challenges will help you overcome obstacles that will come your way from time to time. It’s impossible to increase the scope of our worldview when all that we are focused on is ourselves. In this way, life can be thought of as a prism. What you perceive depends on how you turn the glass. Your retina is a prism. It has photoreceptors for color vision, it has melanopsin for SCN function, it has orexin neurons, it has neuropsin, and it has Müller cells that are optical fibers (picture below) to refract the light.

Müller cells are radial glial cells spanning the entire retinal thickness. Muller cells act as astrocytes do in forming the blood-brain barrier.  Müller cells have an extended funnel shape, a higher refractive index than their surrounding tissue, and are oriented along the direction of light propagation in the eye.  Müller cells provide trophic and anti-oxidative support for photoreceptors and neurons and regulate the tightness of the blood-retinal barrier. I believe IR-A light has a massive effect on cytochrome c oxidase to help regenerate damaged retina.

While the exact mechanism of PBM in treating retinal regeneration is not entirely clear in the literature I have reviewed, I believe I have found the likely target.  I believe that mitochondria in the Muller glial cells provide a massive source of red photons that are absorbed by the copper subunit of the terminal enzyme, cytochrome c oxidase (CCO).  PBM likely affects other parts of the electron transport chains of mitochondria like the Q-cycle as well. I believe the light absorbed by CCO enhances the ability of the mitochondria to catalyze the reduction of oxygen to produce ATP more efficiently.   It also augments the creation of water, which becomes a source of delocalized electrons and protons that can be used to regenerate damaged parts of the retina.

As CCO redox activity increases from PBM therapy, oxygen consumption also increases in the retina, leading to a rise in the rate of oxidative phosphorylation as well as cellular oxygen metabolism. Since neurons in the retina have an increased reliance on mitochondrial oxygen metabolism compared to most other cell types, PBM has already been shown to affect neuronal functions significantly by raising ATP production.  UV light seems like it would limit regeneration by this mechanism based on the slide above.

Traumatic stress of any type can elevate glutamate to abnormally high levels in the brain/retina. Light stress increases glutamate via the activation of orexin A in the retina.  A brain injury or stroke causes glutamate to flood the injured area.

Astrocytes make up the blood-brain barrier.  They release vitamin C to stress to alter metabolism to help NAD+ recycle faster to create ATP.  In the retina, Muller cells do the same thing for the neurons of the retina.  The glial Müller cells in the retina, regulate the glutamate cycle to prevent damage in oxidative stress conditions of the photoreceptors.

PBM likely increases the uptake of glutamate, helping the Müller cells to protect the retina.  They are more directly involved in the regulation of the synaptic activity in the inner retina.  They help organize the chaos that light creates in the retina.  Orexins seem evolved to deal with the chaos the sun creates and not any man-made light. Man-made light seems to unleash orexin A so that the PVN is chronically turned on to give us a syndrome that mimics adrenal fatigue.  It should not surprise you because light stress stimulates orexin A and this activates the PVN.  This also releases glutamate and an excessive amount of Vitamin C.  When Vitamin C is exhausted none of the catecholamine molecules associated with adrenal fatigue can be made.  This is why adrenal fatigue is not an adrenal disease.  It is a disease of the eyes, orexin, and the PVN due to excessive glutamate release and excessive use of Vitamin C so that dopamine, epinephrine, and noradrenaline can’t be made.

The light is broken down into its parts to impart information to the retina. In this way, Perception is a prism, and the retina is like shot silk – the quality of information it imparts depends on the quality and quantity where the light hits.

Counterintuitively, the retina of the vertebrate eye is inverted with respect to its optical function and light must pass through several tissue layers before reaching the light-detecting photoreceptor cells.  The reason for this I laid out in my Vermont 2017 talk on YouTube.

In mammals and humans, the extent of spontaneous repair after retina injury or disease is either non-existent or extremely limited (Karl and Reh, 2010). Rather than regenerate, damaged mammalian retinas commonly undergo reactive gliosis and scar formation (Bringmann et al., 2006). (See below)

This lack of a complete regenerative response to damage directly limits the treatment options for retinal-based diseases such as age-related macular degeneration or Stargardt’s disease.  The use of PBM seems to help use the Muller cells to help regenerate damaged retinas.  I have had quite a bit of success with this in the last three years.  I read some papers on retinal damage in zebrafish and realized that Muller cells were the key to understanding how to regenerate damaged retinal tissues.

The retina forms from the central nervous system (CNS) and develops into a three-layered structure consisting of seven main types of cells and numerous other cell types identified by single-cell RNAseq (Macosko et al., 2015). The structure, function, cell types, and genes expressed in the retina are largely conserved among vertebrates, supporting the notion that information gained from models capable of spontaneous regeneration likely applies to mammals whose regenerative capacity varies.  It appears humans have a lot in common with zebrafish based on my recent experience with acute macular degeneration.

The information the retina creates is stored electromagnetically in coherent domains of water in cells like the Muller glia and in the CSF that surrounds the key areas of the brain that interact with the environment.  CSF is made by the choroid plexus in the brain. CSF is an ultrafiltrate of the blood.

OREXINS AS A PRISM

I’ve taught my readers about every single part of the retinal prism, but I’ve saved the orexin neurons for last.  They are intercalated deep into the retina of every vertebrate on planet Earth. They are the rare neurons in the entire human brain. Scarcity creates its value to signaling when it comes to light.  Light strikes things and changes them in ways our retina cannot sense.  This makes light the most powerful change stimulus behind the evolutionary adaptation.

Our prism can become our prison if we don’t understand how it operates and with what light it is designed to work.

With change being an inevitable element in our lives, we have only two options. Either embrace it and live life to the fullest or be stuck in the comfort zone of a compromised life.  Orexins make sure vertebrates never stay in their comfort zone of life.  They create stress for us to adapt to.  This response must be controlled.

Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for a (previously) orphan G-protein-coupled receptor (GPCR). I spoke about them here over ten years ago. They are multitasking peptides involved in many physiological functions, including regulation of feeding behavior, wakefulness and autonomic/neuroendocrine functions, and sleep/wakefulness states in mammals. There are two isopeptides of orexin, orexin A and orexin B, which are produced from a common precursor peptide, pre-pro-orexin. UV and red light operate on these two orexins from sunlight.

The structures of orexins, as well as orexin genes, are highly conserved throughout mammalian species, suggesting strong evolutionary pressure has maintained these structures for hundreds of millions of years.  In this way, orexins are like DHA they haven’t changed in hundreds of millions of years of vertebrate evolution.  Note in Orexin -A below the disulfide bridges.  The photosensitivity of protein-bound cysteine residues has been shown to depend on the redox state of the microenvironment (Augenstein and Ghiron 1961; Dose and Rajewsky 1962; Augenstein and Riley 1964; Dose 1964, 1967; Fiore and Dose 1965; Grist et al. 1965; Risi et al. 1967; Koudelka and Augenstein 1968)

This data set correlates with the observation by Petersen et al. made in 1999, that cystine residues (cysteines involved in disulfide bridges) have a clear preference for aromatic residues as spatial neighbors.  Note that orexin has one tyrosine adjacent to its S-S bond.  Why is this important?  Recall that all cells release ultra-weak UV light.  Going further, vertebrate eukaryotes tend to release less ultraweak UV light unless the redox state is low.  When it is low eukaryotes release significantly more ultraweak UV.  The excessive ultraweak UV light then disrupts the S-S of orexin A and this changes the tertiary and quaternary protein folding of orexin and alters its physiologic signaling optically.  These photodynamic reactions allow for a temporally and spatially controlled and reversible modification of the surface of orexin A and, hence, can be used to produce functional interfaces that change signaling.

It has been reported that the UV illumination of Tryptophan and Tyrosine residues gives rise to delocalized electrons.  UV light can also liberate hydrogen from aromatic amino acids into the hydration shell.  The H-atom ejection from these amino acids was written about decades ago.  (Vladimirov et al. 1970; Feitelson 1971). The role of the hydrated electron in photo-reduction of cystine in the presence of indole (melatonin is an indole) led to the proposal of a possible mechanism behind this phenomenon over 50 years ago (Grossweiner and Usui 1970).  Few go back and read those papers to understand what orexins are really doing.  The liberation of these electrons and protons is what changes the hydrogen bonding network to become coherent domains.  Orexins are the gatekeepers that force water to take on a hexagonal form to become quantum coherent in the brain.

The connection of orexin to melatonin is more important to make.

Melatonin and dopamine are known to be critical in regenerating all human photoreceptors (see below).  The problem is we do not know exactly why.  Melatonin has two receptors, MT1 and MT2.   The pathophysiological function of the melatonin MT1 and MT2 receptors has not yet been well-clarified.  The MT1 receptor is involved in the regulation of the circadian rhythm.  MT2 is not.  MT2 receptors are located in the reticular thalamus which is the non-REM sleep area.  Non-REM sleep disorders are also called arousal disorders. Non-REM parasomnias involve physical and verbal activity. You are not completely awake or aware during these events, are not responsive to others’ attempts to interact with you, and usually don’t remember or only partially remember the event the next day.

The MT1 receptor is in the locus ceruleus and lateral hypothalamus where REM areas exist.  This is the same area where orexin neurons project to.  When these orexin neurons are destroyed there we also see a REM sleep disorder develop called narcolepsy.  People with narcolepsy frequently enter REM sleep rapidly with sleep onset. This usually happens within 15 minutes of falling asleep day or night. Also, muscle weakness or dream activity that is associated with REM sleep can occur during wakefulness or be absent during sleep.  REM normally occurs in short periods and is characterized by a decrease in muscle tone and is associated with profound sympathetic activation (PVN), including increased heart rate, breathing, blood pressure, and temperature.

The lengths and structure of orexins suggested that orexin B is the ancestral form of the orexin neuropeptide. In mammals, orexins bind to two subtypes of GPCRs, i.e., orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R).

I believe one orexin works best with UV light signaling and the other is optimized by red light.  One reacts best with fast-traveling red light (orexin B) and the other with slower-traveling UV light  (orexin A) in our tissues.   Phylogenetically, the orexin system is present exclusively in vertebrates so this puts them around 650 million years old.

Orexin A is a 33-amino-acid peptide with an N-terminal pyroglutamyl residue, two intrachain disulfide bonds, and C-terminal amidation. Strikingly, this structure is completely conserved among all mammalian species so far identified in the literature.  This means orexin A is the same in humans, gorillas, rats, mice, cows, pigs, sheep, dogs, seals, and dolphins.  Very few proteins have been found to have this long-term evolutionary lineage.

Most of you have learned from me there are a lot of photoreceptors in the eye like melanopsin, melatonin, neuropsin, B12, dopamine, melanin, cytochrome c oxidase,  nitric oxide, and heme proteins like catalase in RBCs etc. (see above and below)

The central retinal pathways in the retina of all mammals contain orexin neurons that project to the areas of the brain adjacent to CSF pathways.  Orexin-producing neurons (orexin neurons), in the lateral hypothalamus, receive input from the forebrain structures including the extended amygdala and nucleus accumbens (NAc)—which are implicated in the processing of emotion and motivation—and send output to brain stem regions, which are implicated in the regulation of wakefulness. I told you in the cold thermogenesis series that sleep was our primordial state, and we evolved wakefulness.  I believe the orexin neurons were key in this transition.  Orexin made water more quantum coherent so more energy could be harvested to allow wakefulness to emerge.  Orexin neurons play an important role as a link between emotional states and wakefulness states.   Any acute stress activates orexins neurons, and this includes modern light stress.  This is why I have believed for 15 years that adrenal fatigue is a disease of the periventricular nucleus.  I believe orexins are the fuse that begins the process.

There are only 50,000–80,000 orexin-producing neurons in the human brain, located predominantly in the perifornical area and lateral hypothalamus. The hypothalamus sits adjacent to the third ventricle which is filled with CSF. CSF is 99.8% water created by mitochondria.  Let’s talk about the prism that your eye clock sits in.

Light transmission via the retina interacts with the amacrine cell level in the retina which in turn activates both orexin systems. The orexin systems modulate the stress response in mammals. The orexin system was initially suggested to be primarily involved in the stimulation of food intake, based on the finding that central administration of orexin-A and -B increased food intake. In addition, they stimulate wakefulness, regulate energy expenditure, and modulate the visceral function and brown fat activation.

Many studies support that the orexin neurons regulate brown adipose tissue (BAT) activity via the sympathetic nervous system to enhance energy expenditure.  This is the basis of my cold thermogenesis protocol.

Orexin promotes wakefulness. I believe inhibition of orexin function is how general anesthetics work.  Right now, most anesthesiologists still have no idea how the drugs they use daily work.  Studies have indicated that a major role of the orexin system is to integrate metabolic, circadian, and sleep debt influences to determine whether an animal should be asleep, or awake and active.  Orexin B are proteins that absorb the slowest form of light in tissue to maximize the fidelity of the signal. Orexin A neurons strongly excite various brain nuclei with important roles in wakefulness including the dopamine, norepinephrine, histamine (all made from aromatic amino acids), and acetylcholine systems, and appear to play an important role in stabilizing wakefulness and sleep (adenosine).  Adenosine is activated by IR-A light. The sleep-promoting action of adenosine can be reversed by orexin A applied to the lateral hypothalamus, by exciting glutamatergic input to orexin neurons via the action of orexin receptor 1.  I believe it is the ultraweak release of UV light that disrupts the S-S bond of Orexin-A that cause sympathetic outflow to increase. This leads to REM sleep disorders = narcolepsy.

The discovery that an orexin receptor mutation causes the sleep disorder canine narcolepsy in Doberman Pinschers subsequently indicated a major role for this system in sleep regulation. Narcolepsy is a REM sleep disorder. Genetic knockout mice lacking the gene for orexin were also reported to exhibit narcolepsy.

In humans, narcolepsy is associated with a specific variant of the human leukocyte antigen (HLA) complex. A lack of either red light or UV light is how narcolepsy begins.  It begins with poor light signaling in the prism of the retina. Light changes the charge density of the retina.  The proof is found in genome-wide analysis studies that show that, in addition to the HLA variant, people with narcolepsy also exhibit a specific genetic mutation in the T-cell receptor alpha locus. I spoke about the HLA complex in the brain-gut series when I explained how the chimp brain evolved into the homo sapien brain using the HLA complex.  I think orexins helped fuel the transition.

In conjunction, there are genetic anomalies that cause the immune system to attack and kill the critical orexin neurons.  Once they are destroyed, they do not come back.  Hence the absence of orexin-producing neurons in people with narcolepsy appears to be the result of an autoimmune disorder.  Can we see the effect of these changes elsewhere in the brain?  We do.  We see it in the hydrogen bonding networks of water in cells, in the blood, and in the CSF.

All paths can be seen, through the prism of fate.  Sunlight is the Windex our watery eyes require.  The periventricular nucleus controls our sympathetic response by how it reacts to the orexin signal from the central retinal pathways.  Moreover, the choroid plexus (CP) of the brain that creates CSF has recently been implicated in the regulation of circadian rhythmicity and therefore, it is now recognized that the functions of the CP cannot be limited to those listed in textbooks. Given the strong circadian influence over the sleep-wake cycle and orexinergic signaling, the role of the CP in modulating orexinergic signaling via circadian influence is worth further study. Furthermore, considering that the sleep-wake cycle modulates additional homeostatic processes such as amyloid-β and glymphatic clearance, the hydrogen bonding networks in the CP may also have a significant influence on the activity of these functions.  People forget that the S-S bond in orexin-A induces proteins to misfold due to the effect of UV light on this bond.  Brains with neurodegeneration all have low redox states and this means they will release a lot more ultra-weak UV light.  This light will destroy orexin-A and lead to protein misfolding at a log rate.  As this light stress develops, glutamate rises and the BBB becomes leaky.  The process progresses and gets worse.

The autonomic nervous system has two main arms, sympathetic and parasympathetic. The vagus is part of the parasympathetic system that lowers the stress response in the brain stem.  The periventricular nucleus is one of the key targets of the orexin neurons. Stressor activity increases chronically when the sympathetic system is constantly turned on. The sympathetic system outflow of the stress stimulus begins in the paraventricular nucleus (PVN). The vagus nerve is the major outflow tract that is the calming portion of the ANS and antagonizes the PVN to lower the stress response.  It has an amazing effect on the hexagonal prisms in CSF in the 4th ventricle.  This signal can be turned on and off by the light that comes through the prism of our retina.  This is why the light you allow is critical in signaling in how it changes hydrogen bonding in water.

Balancing both arms is critical in avoiding diseases, and creating an allostasis in optical signaling.  The light in the environment destroys that balance.  The autonomic nervous system tries to create order from the chaos in light.  It too is another prism.  The key to the orexin prism is found in its 33–amino–acid peptide sequence that has two intrachain disulfide bridges formed by four cysteine residues (C6–C12 and C7–C14).  You might remember I important I told you cysteine was here.

Cysteine has something in common with orexin Cysteine is the rarest amino acid and being rare means it increases signal fidelity.  Eliminating correlated noise without changing other input properties substantially decreased the accuracy with which a cell’s spike outputs encoded light inputs in retinal ganglion cells. Thus covariation of excitatory and inhibitory inputs in the orexin system can be a critical determinant of the reliability of neural coding and computation in its target in the brain.

Orexin neurons widely project to all regions of the brain including the hypothalamus (de Lecea et al., 1998; Peyron et al., 1998), thalamus, cortex, brain stem, and spinal cord (van den Pol, 1999). There aren’t many of them, but their impact on water chemistry in us defines a non-linear stimulus where a small stimulus leads to a massive change.  

Orexin input to brain regions important for arousal, such as the locus ceruleus, help to regulate the response to a stressor (Hagan et al., 1999). Moreover, orexin-containing nerve terminals project to stress-sensitive centers such as the amygdala and bed nucleus of the stria terminalis (Date et al.,1999). Orexin neurons also project to the paraventricular nucleus of the hypothalamus (PVN) (Winsky-Sommerer et al., 2004), where neurons expressing corticotropin-releasing hormone (CRH = cortisol) initiate the Hypothalamic Pituitary Adrenal (HPA) Axis.   This forms half of the circadian mechanism of cortisol and melatonin. 

Further, orexin neurons densely project to the paraventricular nucleus of the thalamus (PVT) (Kirouac et al., 2005), which plays a role in regulating neuroendocrine and behavioral adaptations to severe or chronic stress (Hsu et al.,2014). Specifically, orexins may influence gene expression of the CRH type 1 receptor (CRH1R) in the paraventricular nucleus of the thalamus (Heydendael et al., 2012, 2011), and this brain region may then regulate the HPA axis via multisynaptic pathways through the BNST to the PVN. The orexin neuropeptides orexin A and orexin B interact with noradrenergic, cholinergic, serotonergic, histaminergic, and dopaminergic systems in the brain, in addition to the HPA axis (Sutcliffe and de Lecea, 2000). Thus, orexins have the potential to regulate the stress response through actions at multiple projection sites.  All mental disorders likely begin with orexin dysfunction.

CSF-contacting neurons are present in all vertebrates and are located mainly in the hypothalamic area and the spinal cord. The hypothalamus lies below the hypothalamic sulcus separating it from the thalamus above. Like the thalamus, a thin vertical space filled with CSF called the 3rd ventricle is positioned midline between the two halves of the hypothalamus thalamus. The blood-brain barrier is absent around the vagal vomiting center of the 4th ventricle so that it can monitor the blood for changes. The blood-brain barrier is also absent around the various areas in the hypothalamus where orexin targets land their signaling.  

The stimulus of light from the orexin prisms in our retina changes the CSF’s hydrogen bonding networks to a hexagonal arrangement that allows for another prism to be built in water that stores electromagnetic information to make the brain quantum coherent.  Full-spectrum sunlight reaching the brain creates more coherent domains in water. Normally water is only 40% quantum coherent.  From here on out you should realize that coherent domains should be regarded as long-range ensembles of electrons and protons of exclusion zones inside the water that has the superconductive ability at room temperature. This type of water is a plasma filled with electrons and protons.  Biological water has unique characteristics that make life possible.

SUMMARY

Water (H2O) is the third most common molecule in the Universe (following the H2 and CO molecule), and its standard chemical structure, based on the hydrogen bond, is actually confined by a simple scheme of charges interacting via static Coulomb forces; that is, it is totally reliant on electrostatics and omits all mention of electrodynamics and the consequent radiation field. It has been speculated that a large percentage of effects in condensed matter physics make use of the radiation field in one way or another but it still doesn’t seem to have found a place in much of basic chemistry. In biochemistry, no one seems to realize how important these effects are.  In biological systems almost all water is within a fraction of a micron or less from a surface or molecular backbone and so is interfacial water, which behaves in a quantum coherent manner. This occurs because as hydrogen bonds change, the Coulomb law of electrostatics does not apply to it. In these circumstances, similar charges become attractive making water react homogeneously. This water changes proteins into LED diodes capable of moving electrons around using light inside of tissues.  Biology itself depends on this, so as to allow the accumulation of tissues from negatively charged cell bodies.

Biological water is paramagnetic meaning that it holds a magnetic charge.

Water has a dipole moment and is, therefore, subject to paramagnetism. Chemical bonds (including covalent, ionic, hydrogen, and van der Waals types) have been commonly assumed to be dominating for biological organization and activity. However, these bonds represent forces acting at short distances in the nanometer region. Biological systems maintain coherence at every dimension scale because of how water is changed by our molecular protein prisms in cells. Long-range coherence, large-distance cooperation, and the whole-body control are significant properties of biological systems.

According to Giuliano Preparata, Emilio Del Giudice, and colleagues water water molecules at the interface surface act like a new chemical species and can change rapidly in cells. This clustering of hydrogen bonds imparts a crystalline likeproperty to the water. It become more like a liquid crystal.  In the bodies of living organisms, the clusters form hydration layers around biological molecules. Orexins are today’s example.  It is known from electronics that different patterns which contain information which result within a cluster depending upon its structure of the crystal.

Thus, depending on its structure, each molecule has an oscillatory pattern (resonance frequency) that can be determined by spectroscopy. It is known, through spectrographic analysis, that water and other dipole molecules are able to be entrained to exogenous oscillatory patterns by rearranging their cluster patterns. The cluster rearrangements then resonate with the entraining frequency of sunlight to do the things life can do.  This water is called a coherent domain.

Water becomes something unique when sunlight interacts with it in our cells.

Within the CD water, molecules oscillate between the ground state and an excited state close to the ionizing potential of water and, therefore, contain close to a million almost-free electrons. Those electrons are used to sculpt the physiology of life.

Quantum Electrodynamic (QED) field theory has produced a vision of water in a liquid state as a medium, which for a peculiarity of its molecular electronic spectrum reveals itself as an essential tool for long-range communications, being able to change its supra-molecular organization in the function of the interaction with the light in the environment.   Orexins have the biggest prism effect of making water the stage on which life performs on.

CITES

https://www.pnas.org/doi/10.1073/pnas.0611180104

Myung J, Schmal C, Hong S, et al. The choroid plexus is an important circadian clock component. Nat Commun2018; 9: 1–13.

Xie L, Kang H, Xu Q, et al. Sleep drives metabolic clearance from the adult brain. Science 2013; 342: 373–377.

Kang J, Lim M, Bateman R, et al. Amyloid-ℬ dynamics are regulated by orexin and the sleep-wake cycle. Science2009; 326: 1005–1007.

Spector R, Snodgrass S, Johanson C. A balanced view of the cerebrospinal fluid composition and functions: focus on adult humans. Exp Neurol 2015; 273: 57–68.

Richardson SJ, Wijayagunaratne RC, D’Souza DG, et al. Transport of thyroid hormones via the choroid plexus into the brain: the role of transthyretin and thyroid hormone transmembrane transporters. Front Neurosci 2015; 9: 66.

Myung J, Wu D, Simonneaux V, et al. Strong circadian rhythms in the choroid plexus: implications for sleep-independent brain metabolite clearance. J Exp Neurosci 2018; 12: 1179069518783762.

 

I received the following email in May of 2014.

“Dear Dr. Kruse –

I am reaching out to you for your advice. 10 years ago, when we were 32, my friend was diagnosed with pulmonary hypertension, usually diagnosed in elderly patients. The doctors had never seen it anyone so young get this disease.

After a period where she was told she would die, she found a specialist who got her on a program that has been working well and she has been living with it since 2008.

Four months ago she started to decline and was in and out of the hospital with pneumonia. She was most recently admitted to UCLA for 3 weeks with inflammation levels over 100 in her entire body.

The PH has progressed and now the doctors also suspect PVOD.

Her pulmonary lymph nodes are all glowing on the scans they also suspect lymphoma, although she does not have any other markers for that.

However, my friend’s husband tells me that really the doctors have NO IDEA what is going on with her fundamentally they seem stumped. She is a complete mystery to them. I feel this will not be a mystery to your community.  This is why I am sending this email to you.  I hope that is OK.

They want to do a lung biopsy but fear she is too fragile. She has been sent home and is due back in the hospital in 4 weeks when they will re-test her inflammation levels.

I would appreciate any feedback you may have, Dr. Kruse.

Thank you in advance for your help.

She lives in Los Angeles, California her whole life and works at Qualcomm.”

My ANSWER was given on 5/31/2014:

The environment is everything you see, but more importantly, everything you don’t see but your cells sense.

UV, IR, other EMF both non-native and native, magnetism, air quality, water quality (we can’t see how high something is in deuterium), food quality. All of these radically affect the lung surface topology in your friend because of the fake light and nnEMF in LA. She and her husband really need to do a consult with me and consider becoming a patient of mine after I do the consult if they agree with my work up and plan of action.  I want them to both know LA is also the home of horrible atmospheric pollution that fills the basin DAILY. The amount of RF from the broadcast is off the chain and it has altered the Van Allen belts above their heads to limit her ability to make Vitamin D from the Sterols in her skin.  This has increased her risk of PH.  The nnEMF of LA and its population is problem number two.

It is no wonder to me why she has a serious lung disease. It also blocks the amount of UVA, UVB, and IR light from the sun that gets through the atmosphere in LA and SD to help her regenerate and this ruins both autophagy and apoptosis in mitochondrial in her lungs. Because of these atmospheric changes, even in sunny southern California, you may not get enough balanced UV and IR sunlight) on your body surfaces. The lung is one of the surfaces where topology and the topologic charge are massively important in the control of hydrogen flow in her body especially in mitochondria.  At night, her body may not even realize it’s night due to lack of connection to the earth and artificial lights, because NO ONE at UCLA even knew that melanopsin was present in the eye, skin/fat to cause chronic inflammatory damage. In fact, the skin damage she got from the blue light likely made her lungs worse daily. Why? All opsin are loosely bound to Vitamin A and as Vitamin A drops it causes circadian mismatches at all surfaces because melatonin levels drop and this ruins cell membrane function which the lung relies upon.

Add in makeup, her clothing, the use of sunscreen, makeup, and sunglasses that are trendy in LA and you see it all unfold in front of your eyes. It is not a rare problem in LA.

FOLLOW UP done yesterday:  This lady and her husband did many consults with me and they became clients of mine in El Salvador.  She called me and her latest follow-up at UCLA shows she has no evidence of PH 6 years later.  She no longer works for Qualcomm and she now resides in Central America at the 9th latitude.  She also told me she never got COVID and had no pulmonary flareups during the pandemic.

Artificial light exposure at night blunts melatonin secretion and melatonin is WHAT REPAIRS mtDNA and increases mitophagy which is what autophagy is called in mitochondria. Your friend needs this big time because she is getting ready to lose apoptosis next and she already might have if her nodes are lymphoma (wisdom of May 2018 webinar). This is worse for young children or people who live in cities with a big nightlife and with lots of people who use technology devices (LA). New parents and big city DWELLER should consider some sort of screen-time-restriction and blue blockers for their eyes and skin.  Vitamin D via your skin is crtical to reversing lung diseases.

CITES

https://twitter.com/DrJackKruse/status/1593636711514472449

https://twitter.com/DrJackKruse/status/1593638139863736320

https://twitter.com/DrJackKruse/status/1593637583656984579

https://twitter.com/heniek_htw/status/1593644489268133888