CPC #72: CAN YOU CREATE PROPAGANDA TO SELL ART?

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I dislike Thanksgiving but I have a tradition where I retell my family the story of how the CIA used the artworld to change public opinion and this program was used to help assinate a president when it became clear that human perception could be harnessed by propaganda.  Part of this story was retold to you in the podcast above.  Here is the second part of the story for you to digest once you finish your Thanksgiving dinner today.  I am warning you it may give some of you indigestion.

When I teach people about Bitcoin, I have two go-to stories about asymmetric values to explain how something worth so little can grow to something beyond your imagination.  One is the Louisiana Purchase, and the other is Gertrude Stein’s experience with Picasso.

By 1905, Picasso became a favorite of American art collectors Leo and Gertrude Stein. Leo told his sister that his work would become iconic and valuable.  She famously told Picasso I wouldn’t say I like your work, but I trust my brother’s eye for value.  She began to collect Picasso’s early works for 5-20 dollars a painting.  Today, some of those paintings are worth 400 million dollars in private peer-to-peer deals.  These deals mimic the peer-to-peer network in Bitcoin.  The value of Bitcoin has gone from 1 cent to 69,000 in 13 years.

Alice B. Toklas (pictured above on right) is remembered for being Gertrude Stein’s (left) great love and writing her unusual, revered memoir-disguised-as-cookbook chronicling their life together. On September 8, 1907, her first day as an American expat in Paris, Toklas met Stein. The two fell instantly in love and remained together for the next 39 years until Stein’s death in 1946.

After Gertrude died, her collection of 47 paintings (38 of which were by Picasso) was bequeathed to her nephew but remained on the walls of Toklas’s home. Gertrude’s nephew eventually passed ownership on to his three children, who decided to sell when Toklas died in 1967.  Nelson Rockerfeller mother founded the Museum of Modern Art in NYC, and Nelson Rockerfeller was given the chance to buy from Stein’s collection first by the political powers that were in place at this time.

The number of MoMA-CIA crossovers is highly suspicious, to say the least when one reviews the history.

In the years since his death in 1973, Picasso’s stature as an artist elevated to the highest ranks, with some of his works going for more than $100 million in public auctions and reportedly at even higher sums in private deals. He remains the top-grossing artist at auction worldwide, raking $245 million across 3,400 lots in 2020 alone.  He is, in many ways, today’s “Bitcoin Standard” of the art market.

For example, Picasso’s Delacroix-inspired Les femmes d’Alger ‘Version O’ (1955) for $179.4 million in 2015 to Steve Wynn.

Femme Assise, pictured above, sold for 63 million dollars.  It depicts French artist and model Fernande Olivier, who went with Picasso to a remote village in Spain during the summer of 1909. While there, she posed for a number of his pictures.

PROPAGANDA AROUND ART WAS BORN IN TULANE UNIVERSITY’S MK-ULTRA

The Cold War was the most powerful macropolitical thing on the planet in the late 1940s and 1950s.

The CIA fostered and promoted American Abstract Expressionist painting worldwide for over 20 years.  The USSR of Stalin post WW2 was about total centralization in all things.  The CIA began experimenting with decentralization at this time in reaction to absolute centralization in the USSR.

The artists the CIA supported emphasize free, spontaneous, and personal emotional expression, and they exercise considerable freedom of technique and execution to attain this goal, with a particular emphasis laid on the exploitation of the variable physical character of paint to evoke expressive qualities (e.g., sensuousness, dynamism.)  The CIA task was monumental because few Americans liked decentralized art in the 1950s.  MK-ULTRA propaganda techniques were applied to change this perception.  It was so successful that it also bleed into the CIA’s operations involved in the assassinations of JFK and RFK Sr.

This was a period when the great majority of Americans disliked or even despised modern art – President Truman summed up the popular view when he said: “If that’s art, then I’m a Hottentot.” As for the artists themselves, many were ex-communists barely acceptable in the America of the McCarthyite era of the 50s, and certainly not the sort of people usually likely to receive US government backing.

Who were the artists the CIA supported?

Clyfford Still, Theodoros Stamos, Jackson Pollock, Willem de Kooning, Arshile Gorky, Mark Rothko, Lee Krasner, Robert Motherwell, Franz Kline, Adolph Gottlieb, David Smith, Hans Hofmann, Joan Mitchell are a few.

The connection between the CIA and art is improbable until you know what MK-ULTRA was all about.  Many of you heard about this program for the first time in my RFK Jr interview linked above.

This new artistic movement was propped up to be proof of the creativity, intellectual freedom, and cultural power of the US. Russian art, strapped into the communist ideological straitjacket, could not compete.

GENERAL GROVES GOT THIS IDEA FROM BERNAYS AND NAZI PROPAGANDA USED IN WW2

Many have forgotten General Groves was the most powerful man in the USA in WW2.  He controlled the Manhattan Project from start to finish.  He was the architect of the Cold War.  He single handedly reversed the promise that FDR made to Stalin at Potsdam that the USA would rebuild Russia for the sacrifices Russia made in defeating the Nazi’s in Europe.  The picture below is when FDR made this promise to Stalin right before FDR death.

Groves made sure that the DNC had replaced FDR’s Vice President before his fourth term so that Groves could control the power struggle that would result after Germany was defeated.  Groves knew that FDR was sympathetic to Stalin.  Groves wanted to limit emotion in post war politics because he realized that a chronic war was a powerful way to subvert the power in the executive branch.  War allowed for emergency power to be instituted without much controversy.  This allowed the industrial military complex to operate freely and covertly.  General groves wanted this ability to continue after the war.  Groves made sure the OSS office would become a central intelligence post in post war America by installing his own people.  Dulles was his hand picked successor.  Truman was Groves hand picked president because he could be easily manipulated by propaganda Groves created and the CIA propagated.

HOW DID THIS PROPAGANDA MACHiNE WORK IN THE ART WORLD?

The existence of this supportive policy in the art world in post war America, which had been rumored and disputed for many years, has now been confirmed for the first time by former CIA officials. Unknown to the artists, the new American art was secretly promoted under a policy known as the “long leash” – arrangements similar in some ways to the indirect CIA backing of the journal ENCOUNTER, edited by Stephen Spender.

The decision to include culture and art in the US Cold War arsenal was taken as soon as the CIA was founded in 1947 by Truman at General Groves’s request.  This was how the industrial, military complex captured the executive branch of government in the USA.  I covered this in the tweet thread cited below.

Dismayed at the appeal communism still had for many intellectuals and artists in the West, the new agency set up a division, the Propaganda Assets Inventory, which could influence more than 800 newspapers, magazines, and public information organizations at its peak. They joked that it was like a Wurlitzer jukebox: when the CIA pushed a button, it could hear whatever tune it wanted playing across the world.

The following key step came in 1950 when the International Organizations Division (IOD) was set up under Tom Braden. It was this office that subsidized the animated version of George Orwell’s Animal Farm, which sponsored American jazz artists, opera recitals, and the Boston Symphony Orchestra’s international touring program. Its agents were placed in the film industry, in publishing houses, and even as travel writers for the celebrated Fodor guides. And, we now know, it promoted America’s anarchic avant-garde movement, Abstract Expressionism in the art world.

Initially, more open attempts were made to support the new American art. In 1947 the State Department organized and paid for a touring international exhibition entitled “Advancing American Art,” with the aim of rebutting Soviet suggestions that America was a cultural desert. But the show caused outrage at home, prompting Truman to make his Hottentot remark and one bitter congressman to declare: “I am just a dumb American who pays taxes for this kind of trash.” The tour had to be canceled.

The US government now faced a dilemma. This philistinism, combined with Joseph McCarthy’s hysterical denunciations of all that was avant-garde or unorthodox, was deeply embarrassing. Many of you might have forgotten that RFK Sr worked under Joe McCarthy during these anti-communist times and this theme would come back to haunt the Kennedy family in November of 1963 and in 1968.

It discredited the idea that America was a sophisticated, culturally rich democracy. It also prevented the US government from consolidating the shift in cultural supremacy from Paris to New York since the 1930s. To resolve this dilemma, the CIA was brought in to change perception by using mind control techniques developed in the MK-Ultra program.

ALLEN DULLES WAS A GENERAL GROVES ACOLYTE AND HE WAS THE ARCHITECT OF THE KENNEDY DEATHS in 1963 and 1968.

ON APRIL 10, 1953, ALLEN DULLES became the newly APPOINTED DIRECTOR OF THE CIA, and he delivered a speech to a gathering of Princeton alumni. Though the event was mundane, global tensions were running high. The Korean War was coming to an end, and earlier that week, The New York Times had published a startling story asserting that American POWs returning from the country may have been “converted” by “Communist brain-washers.”  This was classic Cold War propaganda born in the work of Edward Bernays. Dulles decided to use this technique on the people of the United States.

Some GIs were confessing to war crimes, like carrying out germ warfare against the Communists–a charge the U.S. categorically denied. Others were reportedly so brainwashed that they refused to return to the United States at all. As if that weren’t enough, the U.S. was weeks away from secretly sponsoring the overthrow of a democratically elected leader in Iran to install the Shah to gain control of the oil fields in the Middle East.  The blow back of this CIA program would haunt future presidents.

DULLES EMPLOYED BERNAYS and GOEBBELS PROPAGANDA MACHINE ON THE US PUBLIC

Dulles had just become the first civilian director of an agency growing more powerful by the day, and the speech provided an early glimpse into his priorities for the CIA. “In the past few years, we have become accustomed to hearing much about the battle for men’s minds–the war of ideologies,” he told the attendees. “I wonder, however, whether we clearly perceive the magnitude of the problem, whether we realize how sinister the battle for men’s minds has become in Soviet hands,” he continued. “We might call it, in its new form, ‘brain warfare.’”

Dulles proceeded to describe the “Soviet brain perversion techniques” as effective but “abhorrent” and “nefarious.” He gestured to the American POWs returning from Korea, shells of the men they once were, parroting the Communist propaganda they had heard cycled for weeks on end. He expressed fears and uncertainty–were they using chemical agents? Hypnosis? Something else entirely? “We in the West,” the CIA Director conceded, “are somewhat handicapped in brain warfare.” This sort of non-consensual experiment, even on one’s enemies, was antithetical to American values, Dulles insisted, as well as antithetical to what should be human values.  Behind the scenes Dulles was building a CIA program to mimic what the communists and Nazi’s had already done.

Newspaper headlines like “New Evils Seen in Brainwashing” and “Brainwashing vs. Western Psychiatry” offered sensational accounts of new mind-control techniques and technologies that no man could fully resist. The paranoia began to drift into American culture, with books like The Manchurian Candidate and The Naked Lunch playing on themes of unhinged scientists and vast political conspiracies.  These current events in the newspapers were like a shark fin breaking the water, announcing to the public that the CIA had an active mind control program at the covert universities in the Deep South.  This is why MK-Ultra was born and bred at Tulane University.  I mentioned this in the RFK Jr Tetragrammaton podcast .

MK-ULTRA AT TULANE linked to museums, the media, and CBS

Three days after his speech decrying Soviet tactics, Dulles approved the beginning of MK-Ultra, a top-secret CIA program for “covert use of biological and chemical materials.” “American values” made for good rhetoric, but Dulles had far grander plans for the agency’s Cold War agenda.

MK-Ultra’s “mind control” experiments generally centered around behavior modification via electro-shock therapy, hypnosis, polygraphs, many forms radiation, artificial light and a variety of drugs, toxins, and chemicals. These experiments relied on a range of test subjects: some who freely volunteered, some who volunteered under coercion, and some who had absolutely no idea they were involved in a sweeping defense research program. From mentally-impaired boys at a state school to American soldiers to “sexual psychopaths” at a state hospital, MK-Ultra’s programs often preyed on the most vulnerable members of society.

The CIA targeted cities in the USA for testing as well.  St Louis and SF were two of the best documented in this program.  The CIA considered prisoners especially good subjects, as they were willing to give consent in exchange for extra recreation time or commuted sentences.  Recall how they tested the SV-40 concentrated virus by the LINAC on an Angola death row inmate in August of 1963 to test their bioweapons to kill Castro.  MK-Ultra gave birth to this program in the bioweapons lab run by Dr. Alton Ochsner (middle below) and Dr. Mary Sherman (second pic below).

Whitey Bulger, a former organized crime boss, wrote of his experience as an inmate test subject in MK-Ultra. “Eight convicts in a panic and paranoid state,” Bulger said of the 1957 tests at the Atlanta penitentiary where he was serving time. “Total loss of appetite. Hallucinating. The room would change shape. Hours of paranoia and feeling violent. We experienced horrible periods of living nightmares and even blood coming out of the walls. Guys turning to skeletons in front of me. I saw a camera change into the head of a dog. I felt like I was going insane.”

Bulger claimed he had been injected with LSD. Lysergic acid diethylamide, or acid, had become one of the CIA’s critical interests for its “brain warfare” program, as the agency theorized it could be useful in interrogations. In the late 1940s, the CIA received reports that the Soviet Union had engaged in “intensive efforts to produce LSD,” and that the Soviets had attempted to purchase the world’s supply of the chemical. One CIA officer described the agency as “literally terrified” of the Soviets’ LSD program, largely because of the lack of knowledge about the drug in the United States. “[This] was the one material that we had ever been able to locate that really had potential fantastic possibilities if used wrongly,” the officer testified.

All this went on right before the bioweapons program that began in the USA in New Orleans in 1950-1964.  You need to understand the timeline of history to understand what is going on today in your world.  Experiments with LSD was the precursor to the SV-40 experiments.

With the advent of MK-Ultra, the government’s interest in LSD shifted from a defensive to an offensive orientation. Agency officials noted that LSD could be potentially useful in “[gaining] control of bodies whether they were willing or not.” The CIA envisioned applications that ranged from removing people from Europe in the case of a Soviet attack to enabling assassinations of enemy leaders. On November 18, 1953, a group of ten scientists met at a cabin deep in Maryland’s forests. After extended discussions, the participants agreed that to understand the value of the drug truly, “an unwitting experiment would be desirable.”

ART AND MK-ULTRA MERGE

The connection between art and propaganda is not quite as odd as it might appear once you see it from this perspective. At this time, the new agency, staffed mainly by Yale and Harvard graduates, many of whom collected art and wrote novels in their spare time, was a haven of liberalism when compared with a political world dominated by McCarthy or with J Edgar Hoover’s FBI. If any official institution was in a position to celebrate the collection of Leninists, Trotskyites, and heavy drinkers that made up the New York School, it was the CIA.

Until now, there has been no first-hand evidence to prove that this connection was made, but for the first time, a former case officer, Donald Jameson, has broken the silence. Yes, he has said, the agency saw Abstract Expressionism as an opportunity, and it ran with it.

“Regarding Abstract Expressionism, I’d love to be able to say that the CIA invented it just to see what happens in New York and downtown SoHo tomorrow!” he joked. “But I think that what we did really was to recognize the difference. It was recognized that Abstract Expressionism was the kind of art that made Socialist Realism look even more stylized and more rigid and confined than it was. And that relationship was exploited in some of the art exhibitions.

“In a way, our understanding was helped because Moscow in those days was very vicious in denouncing any kind of non-conformity to its own very rigid patterns. And so one could quite adequately and accurately reason that anything they criticized that much and that heavy-handedly was worth support one way or another.”

To pursue its underground interest in America’s lefty avant-garde, the CIA had to be sure its patronage could not be discovered. “Matters of this sort could only have been done at two or three removes,” Mr. Jameson explained, “so there wouldn’t be any question of having to clear Jackson Pollock, for example, or do anything that would involve these people in the organization. And it couldn’t have been any closer because most of them were people who had very little respect for the government, in particular, and certainly none for the CIA. If you had to use people who considered themselves one way or another to be closer to Moscow than to Washington, well, so much the better, perhaps.”

This was the “long leash”. The centerpiece of the CIA campaign became the Congress for Cultural Freedom, a vast jamboree of intellectuals, writers, historians, poets, and artists which was set up with CIA funds in the early 1950s and run by a CIA agent. It was the beachhead from which culture could be defended against the attacks of Moscow and its “fellow travelers” in the West. At its height, it had offices in 35 countries and published over two dozen magazines, including Encounter.

SV-40 SIDEBAR OCCURING AT THE SAME TIME THE CIA WAS USING THE ART WORLD

The success of this program preconditioned the CIA to believe they could build a covert bioweapons lab in the USA and hide it below the noses of the public and keep it covert using propaganda.  These same facades where used to link neo-con community of Ochsner to the gay  underground community Clay Shaw and David Ferry were in New Orleans.  This was how the CIA came to link the medical and gay community in the conspiracy to kill JFK.   just look at the familiar links used in the art world via MK-Ultra and the ones I revealed in the RFK Jr podcast.

HOW DID THE CIA USE MODERN ART COVERTLY?  IT CORRUPTED THE MEDIA AT THE SAME TIME

The Congress for Cultural Freedom also gave the CIA the ideal front to promote its covert interest in Abstract Expressionism. It would be the official sponsor of touring exhibitions; its magazines would provide useful platforms for critics favorable to the new American painting, and no one, the artists included, would be any the wiser.

This organization put together several exhibitions of Abstract Expressionism during the 1950s. One of the most significant, “The New American Painting,” visited every big European city in 1958-59. Other influential shows included “Modern Art in the United States” (1955) and “Masterpieces of the Twentieth Century” (1952).

Because Abstract Expressionism was expensive to move around and exhibit, millionaires, and museums were called into play. Nelson Rockefeller, whose mother had co-founded the Museum of Modern Art in New York, was pre-eminent among these. As president of what he called “Mummy’s Museum,” Rockefeller was one of the biggest backers of Abstract Expressionism (which he called “free enterprise painting”). His museum was contracted to the Congress for Cultural Freedom to organize and curate most of its important art shows.

The museum was also linked to the CIA by several other bridges that most of the American public is ignorant of.   This is how the First Amendment of the United States was captured by the CIA.

William Paley, the president of CBS Broadcasting and a founding father of the CIA, sat on the members’ board of the museum’s International Program. John Hay Whitney, who had served in the agency’s wartime predecessor, the OSS, was its chairman. The Whitney museum of modern art sat on 75th and Madison Ave in New York City.  I lived as a child in this neighborhood and was well aware of its history at an early age.  Did you know that Tom Braden, first chief of the CIA’s International Organizations Division (IOD), was executive secretary of the museum in 1949?

Do you know who worked for William Paley in Dallas in 1963 and later became their network star?

Dan Rather used propaganda in his reporting to help his boss cover up the CIA operations that occurred 60 years ago yesterday.

Now dead, Mr Braden lived in Woodbridge, Virginia until 2009, in a house packed with Abstract Expressionist works and guarded by enormous Alsatians. He explained the purpose of the IOD.

Baden said, “we wanted to unite all the people who were writers, who were musicians, who were artists, to demonstrate that the West and the United States were devoted to freedom of expression and to intellectual achievement, without any rigid barriers as to what you must write, and what you must say, and what you must do, and what you must paint, which was what was going on in the Soviet Union. I think it was the most important division that the agency had, and I think that it played an enormous role in the Cold War.”

He confirmed that his division had acted secretly because of the public hostility to the avant-garde: “It was very difficult to get the 1950s anti-communist Congress to go along with some of the things we wanted to do – send art abroad, send symphonies abroad, publish magazines abroad. That’s one of the reasons it had to be done covertly. It had to be a secret.  In order to encourage openness, we believed it had to be secret.”

If this meant that the CIA had to play the role of the Pope to this century’s Michelangelos, well, all the better: “It takes a pope or somebody with a lot of money to recognize art and to support it,” Mr. Braden said. “And after many centuries, people say, ‘Oh look! the Sistine Chapel, the most beautiful creation on Earth!’ It’s a problem that civilization has faced ever since the first artist and the first millionaire or Pope who supported him. And yet, if it hadn’t been for the multi-millionaires or the popes, we wouldn’t have had the art.”

Would Abstract Expressionism have been the dominant art movement of the post-war years without this CIA patronage? The answer is questionable to those outside the art world.  Those inside of it would likely disagree.  I have been of the opinion for a long time now, that it would not be wrong to suggest that when you look at an Abstract Expressionist painting, you are being duped by the CIA propaganda.  Today, I am thankful to bring you this story I have told to my family at Thanksgiving because this year after the Tetragrammaton podcast with RFK Jr you can now fully understand how all the parts fit to explain US history the military wants you to forget.

But look where this art ended up: in the marble halls of banks, in airports, in city halls, boardrooms, and great galleries. For the Cold Warriors who promoted them, these paintings were a logo, a signature for their culture and system, which they wanted to display everywhere that counted. The CIA propaganda program succeeded in a big way.

The Covert Art Operation continues to bleed into the New Orleans bioweapons lab

In 1958, the touring exhibition “The New American Painting”, including works by Pollock, de Kooning, Motherwell, and others, was on show in Paris. The Tate Gallery was keen to have it next but could not afford to bring it over. Late in the day, an American millionaire and art lover, Julius Fleischmann, stepped in with the cash, bringing the show to London.

However, the money that Fleischmann provided was not his, but the CIA’s. It came through a body called the Farfield Foundation, of which Fleischmann was president, but far from being a millionaire’s charitable arm, the foundation was a secret conduit for CIA funds.  This was how Ochsner got his LINAC from a Hill Burton Grant that the politicians who controlled the industrial military complex controlled in the 1950s.  Amazing coincidence don’t you think?

So, unknown to the Tate, the public, or the artists, the exhibition was transferred to London at American taxpayers’ expense to serve subtle Cold War propaganda purposes. A former CIA man, Tom Braden, described how such conduits as the Farfield Foundation were set up. “We would go to somebody in New York who was a well-known rich person, and we would say, ‘We want to set up a foundation.’ We would tell him what we were trying to do and pledge him to secrecy, and he would say, ‘Of course, I’ll do it,’ and then you would publish a letterhead, and his name would be on it, and there would be a foundation. It was really a pretty simple device.”  This is what the CIA did with Dr. Alton Ochsner in the 1950s after the Cutter Incident.

Julius Fleischmann was well-placed for such a role. He sat on the International Program of the Museum of Modern Art in New York board, as did several powerful figures close to the CIA.  Many Americans in 2023 still do not know how art and the CIA were linked by propaganda.

The world today exists on a belief system that “those in power” can outrun the truth by using intelligence agencies and their technology by manipulating money in the art world – without consequences.   The reality of the situation is that the world of art TODAY still is ruled by the consequences that CIA propaganda used to rehypothecate money to manipulate public opinion.  They used the art world to create and steal money forever wars in the pre Vietnam era and today they are creating trillions of dollars in cancer patients to create massive piles of fiat money they can funnel from HHS to the DOD and CIA to run the chronic wars today.

MK-ULTRA DEMISE WAS AT THE HAND OF ANOTHER KENNEDY

In 1977, Senator Edward Kennedy oversaw congressional hearings investigating the effects of MK-Ultra. Congress brought in a roster of ex-CIA employees for questioning, interrogating them about who oversaw these programs, how participants were identified, and if any of these programs had been continued. The Hearings turned over a number of disturbing details, particularly about the 1953 suicide of Dr. Frank Olson, an Army scientist who jumped out of a hotel window several days after unwittingly consuming a drink spiked with LSD. Amid the growing criminalization of drug users, and just a few years after President Nixon declared drug abuse as “public enemy number one,” the ironies of the U.S.’s troubling experimentation with drugs appeared in sharp relief.

But throughout the hearings, Congress kept hitting roadblocks: CIA staffers claimed they “couldn’t remember” details about many of the human experimentation projects or even the number of people involved. The obvious next step would be to consult the records, but that presented a small problem: in 1973, amid mounting inquiries, the director of MK-Ultra told workers, “It would be a good idea if [the MK-Ultra] files were destroyed.” Citing vague concerns about the privacy and “embarrassment” of participants, the men who crafted MK-Ultra effectively eradicated the paper record for one of the United States’ most obviously illegal undertakings. A program born in secrecy would hold onto many of its secrets forever because the government covered its own illegal tracks.

SUMMARY

Remember what John D. Rockefeller promised Congress under the administration of Teddy Roosevelt that the Rockefeller family would bankrupt the US government one day for breaking up the Standard Oil Trust.  The relationship between Modern Art and American diplomacy began during WWII when the Museum of Modern Art was mobilized for the war effort. MoMA was founded in 1929 by Abby Aldrich Rockefeller. A decade later, her son, Nelson Rockefeller, became president of the Museum. In 1940, while he was still President of MoMA, Rockefeller was appointed the Roosevelt Administration’s Coordinator of Inter-American Affairs. He also served as Roosevelt’s Assistant Secretary of State in Latin America.

The Museum followed suit. MoMA fulfilled 38 government contracts for cultural materials during the Second World War and mounted 19 exhibitions of contemporary American painting for the Coordinator’s office, which were exhibited throughout Latin America. Latin America is where Dr. Alton Ochsner made most of his fortune while he was alive.  He offered medical sanctuary to all the dictators of Latin America.

This direct relationship between the avant-garde and the war effort was well suited: The term avant-garde began as a French military term describing vanguard troops advancing into battle.

In the battle for “hearts and minds,” modern art was particularly effective. John Hay Whitney, both a president of MoMA and a member of the Whitney Family, which founded the Whitney Museum of American Art, explained that art stood out as a line of national defense because it could “educate, inspire, and strengthen the hearts and wills of free men.”

Whitney succeeded Rockefeller as President of the Museum of Modern Art in January 1941 so Nelson could turn his entire attention to his Coordinator duties. Under Whitney, MoMA served as “A Weapon of National Defense.” According to a Museum press release dated February 28, 1941, MoMA would “inaugurate a new program to speed the interchange of the art and culture of this hemisphere among all the twenty-one American republics.”

The goal was “Pan-Americanism.” This was the environment that Dr. Alton Ochsner was operating in during the 1950s-60s during the Cutter Incident.  Ochsner Medical Foundation Hospital had every Latin American flag outside of it for close to 40 years.  I know because I saw them every day for 6 years of my residency in New Orleans.

A “Traveling Art Caravan” through Latin America “would do more to bring us together as friends than ten years of commercial and political work.”

When World War 2 ended, Nelson Rockefeller returned to the Museum, and his Inter-American-Affairs staffers assumed responsibilities for MoMA’s international exhibition program: René d’Harnoncourt, who had headed Inter-American’s art division, became the Museum’s vice president in charge of foreign activities. Fellow staffer Porter McCray became the Director of the Museum’s International Program.

Modern art was so well aligned with American Cold War foreign policy that McCray took a leave of absence from the Museum in 1951 to work on the Marshall Plan. In 1957, Whitney resigned his position as MoMA’s Chairman of the Board of Trustees to become United States Ambassador to Great Britain. Whitney remained a trustee of the Museum while he was Ambassador, and his successor as Chairman was… Nelson Rockefeller, who had served as Special Assistant to President Eisenhower for Foreign Affairs until 1955.  Who was his VP?  Nixon.  Who is seated right next to Dr. Ochsner below?  His policies began the The War on Cancer in 1971.  This is another propaganda technique born at the same time the USD dollar was removed from the gold standard. You are all unaware of the tangled webs the CIA has woven to confuse you to get their agenda through.

In 1947, at the very moment that the Advancing American Art show was being recalled, and the United States Government was selling its O’Keeffe’s for fifty bucks a piece (all seventy-nine pieces in the show together brought in $5,544), the CIA was being created. The CIA grew out of “Wild” Bill Donovan’s Office of Strategic Services (OSS), which was the U.S.’s wartime intelligence apparatus. The OSS became the CIA and George H. Bush Father ran that office.

George W. Bush’s grandfather, the late US senator Prescott S. Bush, was a director and shareholder of companies that profited from their involvement with the financial backers of Nazi Germany.

The Guardian newspaper in the UK obtained confirmation from newly discovered files in the US National Archives that a firm of which Prescott S. Bush was a director was involved with the financial architects of Nazism.  He worked directly with Joseph Goebbels the Nazi Propaganda chief.  Imagine that.

His business dealings, which continued until his company’s assets were seized in 1942 under the Trading with the Enemy Act, has led more than 60 years later to a civil action for damages being brought in Germany against the Bush family by two former slave laborers at Auschwitz.  This only caused a minor ripple in the US Press during his pre-election in 2000.  Guess why?  The media was already captured by his friends in the CIA decades before this controversy.

The evidence the Guardian found has also prompted one former US Nazi war crimes prosecutor to argue over 80 years ago that the late senator’s action should have been grounds for prosecution for giving aid and comfort to the enemy.

What is the evidence against the Bush family and their oil empire?

While there is no suggestion that Prescott Bush was sympathetic to the Nazi cause, the documents reveal that the firm he worked for, Brown Brothers Harriman (BBH), acted as a US base for the German industrialist, Fritz Thyssen, who helped finance Hitler in the 1930s before falling out with him at the end of the decade. We now have confirmed published evidence from US government archives that shows Bush was the director of the New York-based Union Banking Corporation (UBC) that represented Thyssen’s US interests and he continued to work for the bank after America entered WW2.

Bush was also on the board of at least one of the companies that formed part of a multinational network of front companies to allow Thyssen to move assets around the world.

Thyssen owned the largest steel and coal company in Germany and grew rich from Hitler’s efforts to re-arm between the two world wars. One of the pillars in Thyssen’s international corporate web, UBC, worked exclusively for, and was owned by, a Thyssen-controlled bank in the Netherlands. More tantalizing are Bush’s links to the Consolidated Silesian Steel Company (CSSC), based in mineral rich Silesia on the German-Polish border. During the war, the company made use of Nazi slave labor from the concentration camps, including Auschwitz.

The ownership of CSSC changed hands several times in the 1930s, but documents from the US National Archive declassified in 2003 that link Bush to CSSC, although it is not clear if he and UBC were still involved in the company when Thyssen’s American assets were seized in 1942.

Three sets of archives spell out Prescott Bush’s involvement. All three are readily available, thanks to the efficient US archive system and a helpful and dedicated staff at both the Library of Congress in Washington and the National Archives at the University of Maryland.  You should fact check Uncle Jack.

The third set of documents, are also at the National Archives, are contained in the files on IG Farben, who was prosecuted for war crimes in Neuremberg.

A report issued by the Office of Alien Property Custodian in 1942 stated of the companies that “since 1939, these (steel and mining) properties have been in possession of and have been operated by the German government and have undoubtedly been of considerable assistance to that country’s war effort”.

Prescott Bush, a 6ft 4in charmer with a rich singing voice, was the founder of the Bush political dynasty and was once considered a potential presidential candidate himself. Like his son, George, and grandson, George W, he went to Yale where he was, again like his descendants, a member of the secretive and influential Skull and Bones student society. He was an artillery captain in the first world war and married Dorothy Walker, the daughter of George Herbert Walker, in 1921.

In 1924, his father-in-law, a well-known St Louis investment banker, helped set him up in business in New York with Averill Harriman, the wealthy son of railroad magnate E H Harriman in New York, who had gone into banking.

One of the first jobs Walker gave Bush was to manage UBC. Bush was a founding member of the bank and the incorporation documents, which list him as one of seven directors, show he owned one share in UBC worth $125.  You may now understand why the Bush family favors a CBDC over Bitcoin now.  You may also understand why the Bush family is no friend to anyone named Kennedy.  They had a hand in JFK and RFK Sr. demises.

The bank was set up by Harriman and Bush’s father-in-law to provide a US bank for the Thyssens, Germany’s most powerful industrial family.

August Thyssen, the founder of the dynasty had been a major contributor to Germany’s first world war effort and in the 1920s, he and his sons Fritz and Heinrich established a network of overseas banks and companies so their assets and money could be whisked offshore if threatened again.

By the time Fritz Thyssen inherited the business empire in 1926, Germany’s economic recovery was faltering under Weimar hyperinflation. After hearing Adolf Hitler speak, Thyssen became mesmerized by the young firebrand. He joined the Nazi party in December 1931 and admits backing Hitler in his autobiography, I Paid Hitler, when the National Socialists were still a radical fringe party. He stepped in several times to bail out the struggling party: in 1928 Thyssen had bought the Barlow Palace on Briennerstrasse, in Munich, which Hitler converted into the Brown House, the headquarters of the Nazi party. The money came from another Thyssen overseas institution, the Bank voor Handel en Scheepvarrt in Rotterdam.

By the late 1930s, Brown Brothers Harriman, which claimed to be the world’s largest private investment bank, and UBC had bought and shipped millions of dollars of gold, fuel, steel, coal and US treasury bonds to Germany, both feeding and financing Hitler’s build-up to war.  Interesting history lesson huh?  I hope you do not choke on your turkey today.

Between 1931 and 1933 UBC bought more than $8m worth of gold, of which $3m was shipped abroad. According to documents now published in many books and FOIA requests, after UBC was set up it transferred $2m to BBH accounts and between 1924 and 1940 the assets of UBC hovered around $3m, dropping to $1m only on a few occasions.

In 1941, Thyssen fled Germany after falling out with Hitler but he was captured in France and detained there for the remainder of the war.

Mind you, there was nothing illegal in doing business with the Thyssens throughout the 1930s and many of America’s best-known business names invested heavily in the German economic recovery.  This seems ironic when you see how the Biden administration treats corporations who do business with Russia today over Ukraine.   The play book continues for the Deep State.

However, everything changed politically after Germany invaded Poland in 1939 because the covert plan could no longer stay hidden. Even then it could be argued that BBH was within its rights continuing business relations with the Thyssens until the end of 1941 as the US was still technically neutral until the attack on Pearl Harbor in 1941. The trouble started on July 30 1942 when the New York Herald-Tribune ran an article entitled “Hitler’s Angel Has $3m in US Bank”. UBC’s huge gold purchases had raised suspicions that the bank was in fact a “secret nest egg” hidden in New York City for Thyssen and other Nazi bigwigs. The Alien Property Commission (APC) launched an investigation.  It turns out the Bush family did hide Nazi assets during the war.  This is how the modern neo-cons were born in the US politics.

There is no dispute over the fact that the US government seized a string of assets controlled by BBH – including UBC and SAC – in the autumn of 1942 under the Trading with the Enemy Act. What is in dispute is if Harriman, Walker and Bush did more than own these companies on paper.

Erwin May, a treasury attache and officer for the department of investigation in the APC, was assigned to look into UBC’s business. The first fact to emerge was that Roland Harriman, Prescott Bush and the other directors didn’t actually own their shares in UBC but merely held them on behalf of Bank voor Handel. Strangely, no one seemed to know who owned the Rotterdam-based bank, including UBC’s president.

May wrote in his report of August 16 1941: “Union Banking Corporation, incorporated August 4 1924, is wholly owned by the Bank voor Handel en Scheepvaart N.V of Rotterdam, the Netherlands. My investigation has produced no evidence as to the ownership of the Dutch bank. Mr Cornelis [sic] Lievense, president of UBC, claims no knowledge as to the ownership of the Bank voor Handel but believes it possible that Baron Heinrich Thyssen, brother of Fritz Thyssen, may own a substantial interest.”

May cleared the bank of holding a golden nest egg for the Nazi leaders but went on to describe a network of companies spreading out from UBC across Europe, America and Canada, and how money from voor Handel travelled to these companies through UBC.

By September May had traced the origins of the non-American board members and found that Dutchman HJ Kouwenhoven – who met with Harriman in 1924 to set up UBC – had several other jobs: in addition to being the managing director of voor Handel he was also the director of the August Thyssen bank in Berlin and a director of Fritz Thyssen’s Union Steel Works, the holding company that controlled Thyssen’s steel and coal mine empire in Germany.

Within a few weeks, Homer Jones, the chief of the APC investigation and research division sent a memo to the executive committee of APC recommending the US government vest UBC and its assets. Jones named the directors of the bank in the memo, including Prescott Bush’s name, and wrote: “Said stock is held by the above named individuals, however, solely as nominees for the Bank voor Handel, Rotterdam, Holland, which is owned by one or more of the Thyssen family, nationals of Germany and Hungary. The 4,000 shares hereinbefore set out are therefore beneficially owned and help for the interests of enemy nationals, and are vestible by the APC,” according to the memo from the National Archives.

The Bush family was caught RED HANDED.

Jones recommended that the assets be liquidated for the benefit of the government, but instead UBC was maintained intact and eventually returned to the American shareholders after the war. Some claim that Bush sold his share in UBC after the war for $1.5m – a huge amount of money at the time – but there is no documentary evidence to support this claim. No further action was ever taken nor was the investigation continued, despite the fact UBC was caught red-handed operating a American shell company for the Thyssen family eight months after America had entered the war and that this was the bank that had partly financed Hitler’s rise to power.

The most sensational part of the story remains shrouded in mystery: the connection, if any, between Prescott Bush, Thyssen, Consolidated Silesian Steel Company (CSSC) and Auschwitz.

Thyssen’s partner in United Steel Works, which had coal mines and steel plants across the region, was Friedrich Flick, another steel magnate who also owned part of IG Farben, the powerful German chemical company.

Flick’s plants in Poland made heavy use of slave labor from the concentration camps in Poland. According to a New York Times article published in March 18 1934 Flick owned two-thirds of CSSC while “American interests” held the rest.

The US National Archive documents show that BBH’s involvement with CSSC was more than simply holding the shares in the mid-1930s. Bush’s friend and fellow “bonesman” Knight Woolley, another partner at BBH, wrote to Averill Harriman in January 1933 warning of problems with CSSC after the Poles started their drive to nationalize the plant. “The Consolidated Silesian Steel Company situation has become increasingly complicated, and I have accordingly brought in Sullivan and Cromwell, in order to be sure that our interests are protected,” wrote Knight. “After studying the situation Foster Dulles is insisting that their man in Berlin get into the picture and obtain the information which the directors here should have. You will recall that Foster is a director and he is particularly anxious to be certain that there is no liability attaching to the American directors.”

John Foster Dulles was the brother of Allen Dulles who JFK fired in 1961 after the Bay of Pigs.  Coincidence?

Continuing the history lesson:  But the ownership of the CSSC between 1939 when the Germans invaded Poland and 1942 when the US government vested UBC and SAC is not clear.

“SAC held coal mines and definitely owned CSSC between 1934 and 1935, but when SAC was vested there was no trace of CSSC. All concrete evidence of its ownership disappears after 1935 and there are only a few traces in 1938 and 1939,” says Eva Schweitzer, the journalist and author whose book, America and the Holocaust, was published in 2004.

Silesia was quickly made part of the German Reich after the invasion, but while Polish factories were seized by the Nazis, those belonging to the still neutral Americans (and some other nationals) were treated more carefully as Hitler was still hoping to persuade the US to at least sit out the war as a neutral country. Schweitzer says American interests were dealt with on a case-by-case basis. The Nazis bought some out, but not others.

The two Holocaust survivors suing the US government and the Bush family for a total of $40billon in compensation claim both materially benefited from Auschwitz slave labor during the second world war.

Kurt Julius Goldstein, 87, and Peter Gingold, 85, began a class action in America in 2001, but the case was thrown out by Judge Rosemary Collier on the grounds that the government cannot be held liable under the principle of “state sovereignty”.

Jan Lissmann, one of the lawyers for the survivors, said: “President Bush withdrew President Bill Clinton’s signature from the treaty [that founded the court] not only to protect Americans, but also to protect himself and his family.”

Lissmann argues that genocide-related cases are covered by international law, which does hold governments accountable for their actions. He claims the ruling was invalid as no hearing took place.

In their claims, Mr Goldstein and Mr Gingold, honorary chairman of the League of Anti-fascists, suggest the Americans were aware of what was happening at Auschwitz and should have bombed the camp.

The lawyers also filed a motion in The Hague asking for an opinion on whether state sovereignty is a valid reason for refusing to hear their case.

The petition to The Hague states: “From April 1944 on, the American Air Force could have destroyed the camp with air raids, as well as the railway bridges and railway lines from Hungary to Auschwitz. The murder of about 400,000 Hungarian Holocaust victims could have been prevented.”

The case is built around a January 22 1944 executive order signed by President Franklin Roosevelt calling on the government to take all measures to rescue the European Jews. The lawyers claim the order was ignored because of pressure brought by a group of big American companies, including BBH, where Prescott Bush was a director.

The US government and the Bush family denied all the claims against them.

In addition to Eva Schweitzer’s book, two other books were published in 2004-05 that raised the subject of Prescott S. Bush’s business history. The author of the second book, John Loftus, is a former US attorney who prosecuted Nazi war criminals in the 70s. At that time he lived in St Petersburg, Florida and earning his living as a security commentator for Fox News and ABC radio, Loftus worked on a novel which used some of the material he has uncovered on Bush. Loftus stressed that what Prescott Bush was involved in was just what many other American and British businessmen were doing at the time.

“You can’t blame Bush for what his grandfather did any more than you can blame Jack Kennedy for what his father did – bought Nazi stocks – but what is important is the cover-up, how it could have gone on so successfully for half a century, and does that have implications for us today?” he said.

Those implications lead right to the death of JFK and RFK Jr.

“This was the mechanism by which Hitler was funded to come to power, this was the mechanism by which the Third Reich’s defence industry was re-armed, this was the mechanism by which Nazi profits were repatriated back to the American owners, this was the mechanism by which investigations into the financial laundering of the Third Reich were blunted,” said Loftus, who is vice-chairman of the Holocaust Museum in St Petersburg.  The US Treasury and Senator Warren wants you to believe in 2023 that Bitcoin is used to launder money when it is clear that this blog is laying the case out why rehypothecation of money is the strong suit of the CIA and all the people affiliated with them.

“The Union Banking Corporation was a holding company for the Nazis, for Fritz Thyssen,” said Loftus. “At various times, the Bush family has tried to spin it, saying they were owned by a Dutch bank and it wasn’t until the Nazis took over Holland that they realized that now the Nazis controlled the apparent company and that is why the Bush supporters claim when the war was over they got their money back. Both the American Treasury investigations and the intelligence investigations in Europe completely bely that, it’s absolute horseshit. They always knew who the ultimate beneficiaries were.”

“There is no one left alive who could be prosecuted but they did get away with it,” said Loftus. “As a former federal prosecutor, I would make a case for Prescott S. Bush, his father-in-law (George Walker) and Averill Harriman [to be prosecuted] for giving aid and comfort to the enemy. They remained on the boards of these companies knowing that they were of financial benefit to the nation of Germany.”

Loftus said Prescott S. Bush must have been aware of what was happening in Germany at the time. “My take on him was that he was a not terribly successful in-law who did what Herbert Walker told him to. Walker and Harriman were the two evil geniuses, they didn’t care about the Nazis any more than they cared about their investments with the Bolsheviks.”

What is also at issue is how much money Bush made from his involvement. His supporters suggest that he had one token share. Loftus disputes this, citing sources in “the banking and intelligence communities” and suggesting that the Bush family, through George Herbert Walker and Prescott, got $1.5m out of the involvement. There is, however, no paper trail to this sum.

The third person going who went into print in the early 2000s on this subject is John Buchanan, 54, a Miami-based magazine journalist who started examining the files while working on a screenplay. In 2003, Buchanan published his findings in the venerable but small-circulation New Hampshire Gazette under the headline “Documents in National Archives Prove George Bush’s Grandfather Traded With the Nazis – Even After Pearl Harbor”. He expands on this in his book – Fixing America: Breaking the Stranglehold of Corporate Rule, Big Media and the Religious Right.

In the article, Buchanan, who has worked mainly in the trade and music press with a spell as a muckraking reporter in Miami, claimed that “the essential facts have appeared on the internet and in relatively obscure books but were dismissed by the media as propaganda and Bush family as undocumented diatribes”.

One of the USAs oldest Jewish publications, the Jewish Advocate, has aired the controversy in detail in print.  Review it at your leisure.

Please recall that President George W. Bush gave us the Patriot Act after “the emergency” of the Twin towers “happened”.  I no longer think the Twin Towers was a terrorist action. I believe Bush pulled a play out from his family blue print.

George H.W. Bush, George W. father, also served as Director of Central Intelligence (DCI) from January 1976 to January 1977, just ten days shy of one full year. Though his tenure was limited, his accomplishments were many, and we are grateful to have served under his leadership. He became president after Ronald Reagan.

There is the link to Big Oil families who had a hand in killing the 35th President of the USA.  MoMA’s John Hay Whitney and Thomas W. Braden were members of the OSS. The OSS became the CIA in 1947.  Never forget what this criminal cabal has done and continues to do.

Game, Set, and Match.

That is conclusion of the RFK Jr interview you did not hear and what i said live on stage in Lisbon, Portugal.

Happy Thanksgiving.

CITES

1.https://www.moma.org/momaorg/shared/pdfs/docs/press_archives/4562/releases/MOMA_1970_July-December_0082_133F.pdf

2. https://twitter.com/DrJackKruse/status/1727329402571067413

3. https://twitter.com/DrJackKruse/status/1727370879460376756

4. https://twitter.com/DrJackKruse/status/1727371695017558289

5. http://www.cambridgeclarion.org/press_cuttings/braden_20may1967.html

QUANTUM ENGINEERING #61: HOW DOES LIGHT CONTROL CONSCIOUSNESS?

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8G mimics a car wreck to the human brain or an NFL LB hit to a QBs head.  These situations induces brain trauma at a space time continuum.  Nothing yet I have said is ground breaking to group of neurosurgeons.  This post below is a groundbreaking mitochondrial medicine lesson.

Today’s lesson on biophysics of consciousness:

Light illuminates the reality of what time and space are to the human experience.  Time and space are mere illusions of our perceptual abilities.  If you use physical forces in Nature we can induce consciousness and we can make it disappear right before your eyes even as nothing on Earth really changes to prove this point.  How?  Watch the video.  Time & space are constructs used by humans to better understand and operate in our world. That there is no such thing as an “external” and “internal” world and what we think we see “out there” is literally occurring and being conceived inside our head at the ATPase level.

Based on physics and biology, this science is unfortunately reality; it turns out that our ability to handle to use sunlight to handle the atomic mass in our ATPase that allows us to be consciousness.  That sole ability that dictates all that we see and perceive in our world.

The colony of mitochondria in the human brain has a massive fleet of ATPase’s in it and the video above shows you how fast its physiology can be altered.  The sunlight in the video did not change.  The amount of deuterium in his head did not change.  But the velocity his body flet did change and that change altered how the nanorotors operates in his head.  He went from energy efficient to energy inefficient in a few seconds when the key environmental variables around light remained constant.  There is a deep lesson in biophysics here.

Proof that this counterintuitive idea is true?

This is time lapsed photography of what happens in neurodegeneration in older humans that over decades.  It does not have to take that long if the atomic mass is added at a faster rate in a younger brain.  This young brain experienced the increased mass via momentum of the force of gravity induced by velocity and not the weight associated with the atomic mass of deuterium.

Deuterium’s higher atomic mass effectively mimics the increase G forces in your ATPase and your brain fails under that weight or mass.  Consciousness declines to neurodegeneration and cognitive decline before your brain fails in death.

Anesthesia also induces this effect on our patients and we take it for granted and never study it.  Do you know that strong magnetic fields induce unconsciousness in living things?  Anesthesia induces dielectric and magnetic flux collapse.

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Decentralized medicine has answers that centralized medicine whiff’s on.

QUANTUM ENGINEERING #60: HOW DOES LIGHT CONTROL POMC CLEAVAGE?

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Most people know about single nucleotide polymorphisms (SNPs) or single amino acid polymorphisms (SAPs), but few people ever get told how they operate in health and disease.

N-acyl amino acids in humans can involve acetylation, and C-terminus amino acids can be involved with methylation.  Both are controlled by light.  This post describes how the process happens.

Modifying the C-terminus of proteins is essential in understanding what light is doing biophysically to determine what biochemistry is possible in a cell.  The C-terminus is also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus.  It represents the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH). When the protein is translated from messenger RNA, it is created from the N-terminus to the C-terminus. The convention for writing peptide sequences is to put the C-terminal end on the right and write the sequence from N- to C-terminus.

For example, while the N-terminus of a protein often contains targeting signals, the C-terminus can include retention signals for protein sorting. The most common Endoplasmic Reticulum retention signal is the amino acid sequence -KDEL (Lys-Asp-Glu-Leu) or -HDEL (His-Asp-Glu-Leu) at the C-terminus. This keeps the protein in the endoplasmic reticulum and prevents it from entering the secretory pathway in a cell.

For example, when the skin over the gut with a massive amount of POMC is not stimulated by solar light, POMC is lightly translated, and Vitamin D levels stay low.  As a result, one form of C-terminal modification is prenylation. During prenylation, a farnesyl- or geranylgeranyl-isoprenoid membrane anchor is added to a cysteine residue near the C-terminus. Small molecular weight, membrane-bound G proteins are often modified this way.  The circadian mechanism in cells operates via G proteins. With proper solar light, prenylation goes smoothly.

The enterocytes in the gut form a barrier.  They include a mechanical boundary against pathogens, antigens, and toxins; the monolayer of intestinal epithelial cells (IECs) represents the human body’s largest contact area with the environment due to villi folding. From their early development in the crypt bottom until the shedding of aged cells at the villus tip, IECs follow a continuous turnover process. This process is controlled by the circadian mechanism in the SCN and transmitted to the gut via the peripheral nervous system and the melanin sheets in the organ of Zuckerlandl, where melanin and POMC reside.

Under physiological conditions, a complex interaction between cytoskeleton rearrangement and tight junction proteins guarantees that the cell shedding itself does not mean a disturbance of epithelial integrity. However, alterations of epithelial integrity lead to the development of gut inflammatory disorders, such as inflammatory bowel diseases (IBDs). IBDs are associated with marked alterations of IECs, leading to increased tight junction permeability, altered cytoskeletal rearrangement, and induction of epithelial cell death with a subsequent loss of barrier function.  All IBDs are linked to poor solar exposure and or artificial light at night on the skin or via the eyes.

In Crohn’s disease, there is Rho-A prenylation, and the absent solar light then changes protein signaling in the enterocytes of the gut.  This links epithelial homeostasis directly to intestinal inflammation.

The peptide created by POMC before cleavage is composed of three such segments: N-POMC, which is located at the N-terminus; ACTH, which is located in the middle; and β-LPH, which is located at the C-terminus. Each of these segments contains one MSH sequence: γ-MSH in N-POMC, α-MSH in ACTH, and β-MSH in β-LPH.

The N-terminus is also known as the amino-terminus, NH2-terminus, N-terminal end, or amine-terminus, is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.  Look at the structure of melanin below when it interacts with an electrophile metal.

When a protein is translated from messenger RNA, it is created from the N-terminus to the C-terminus. The amino end of an amino acid (on a charged tRNA), during the elongation stage of translation, attaches to the carboxyl end of the growing chain. Since the start codon of the genetic code codes for ONLY one amino acid, methionine, most protein sequences start with a methionine (or, in bacteria, mitochondria, and chloroplasts, the modified version N-formylmethionine, fMet). I wrote a blog on that topic on Patreon.  You should have expected I told you this for a reason before the melanin story came out of my mitochondrial mist.  The circadian mechanism operates 100% of the time in a posttranslational fashion.  I laid out that case at the Palestra Health conference when I presented to several politicians and hedge fund managers who were present.  Some proteins are modified posttranslationally, for example, by cleavage from a protein precursor and therefore may have different amino acids at their N-terminus.  Light frequencies can change the N-terminus in proteins.

The N-terminus is the first part of the protein that exits the ribosome during protein biosynthesis. It often contains signal peptide sequences, “intracellular postal codes,” that direct the delivery of the protein to the proper organelle. The signal peptide is typically removed at the destination by a signal peptidase. The N-terminal amino acid of a protein is an essential determinant of its half-life.  This is how the ubiquitin system operates, and quantum mechanics raises or lessens the probability of the likelihood of a protein being degraded. This is called the N-end rule.

The N-terminal signal peptide is recognized by the signal recognition particle (SRP) and results in the targeting of the protein to the secretory pathway. In eukaryotic cells, these proteins are synthesized at the rough endoplasmic reticulum.   Protein N-termini can be modified co – or post-translationally. Modifications include the removal of initiator methionine (iMet) by aminopeptidases, attachment of small chemical groups such as acetyl, propionyl, and methyl, and the addition of membrane anchors, such as palmitoyl and myristoyl groups.  There are many other N-terminus modifications like methylation.  Light frequencies dictate how biochemistry unfolds.  

N-terminus modification is how many diseases begin with aberrant light choices.  Many pharmacological, genetic, and mechanistic studies in mammals have suggested that certain members of the N-acyl amino acids stimulate mitochondrial respiration and whole-body energy expenditure directly. Other complementary studies have also established roles for N-acyl amino acids in glucose homeostasis, adipogenesis, vascular tone, and bone homeostasis.  This explains thoroughly why POMC has the protein construction it does.

The N-POMC is located at the N-terminus ACTH, which is away from the N and C terminus because it is located in the middle of the protein.  This is a deep evolutionary clue about how mammals used ACTH to create sugar from light cleavage.  What should shock you is that each of these cleavage segments contains one MSH sequence: γ-MSH in N-POMC, α-MSH in ACTH, and β-MSH in β-LPH.  This tells you that light and dark are controlling the peptide’s cleavage.

Notably, the functional consequence and enzymatic regulation of each N-acyl amino acid in mammals highly depend on the structural properties of the fatty acid tail group and amino acid head group.

By integrating whole genome sequencing data with N-acyl amino acid levels, one can identify the EPIGENETIC determinants of N-acyl amino acid levels and cluster according to the amino acid head group.   For example, in mammalian heart disease, this is why CYP4F2 is associated with many human cardiometabolic disorders.  Centralized science has now identified the CYP4F2 locus as an epigenetic determinant of plasma N-oleoyl-leucine and N-oleoyl-phenylalanine levels in human plasma, as the papers below show. In experimental studies, it has now been demonstrated that CYP4F2-mediated hydroxylation of N-oleoyl-leucine and N-oleoyl-phenylalanine results in metabolic diversification and production of many previously unknown lipid metabolites in humans with varying characteristics of the fatty acid tail group, including several that structurally resemble fatty acid hydroxy fatty acids. These studies provide a structural framework for understanding the regulation and disease associations of N-acyl amino acids in humans and identify that the diversity of this lipid signaling family can be significantly expanded through CYP4F-mediated ω-hydroxylation.

Modern “centralized chemical biology” relies increasingly on protein chemistry, which ideally allows precise positioning of labels, cargoes, and post-translational modifications (PTMs) in the contexts of complex protein structures. The resulting modified proteins prove helpful in determining proper physiology and Big Pharma therapeutic applications.  They allow us to understand the decentralized cell by the probing and modulating function, as well as their tracking and (un)caging in cells that happen with light and dark cycles.

Big Pharma chemists have developed various methods to control the convergent construction of site-selectively modified proteins. Traditionally, the non-site-selective chemical modification of proteins has relied on the nucleophilicity of the side-chains of natural amino acid residues like lysine (Lys) and cysteine (Cys), as well as protein N-terminus through direct acylation, alkylation and arylation with a wide array of electrophiles.  In chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair. Electrophiles accept electrons in biochemistry. Biological electrophiles are defined as electron-deficient species of chemicals that include heavy metals, environmental pollutants, toxic drug metabolites, flavor enhancers like Splenda, cell signaling mediators, and unsaturated aldehyde products of membrane lipid peroxidation.

When DHA is in the SN-2 position, it becomes planar. This is what turns the central retinal pathways of the retinohypothalamic tracts into a wide band gapped semiconductive LED array that targets melanin all over the brain. Melanin absorbs all light, ROS, and RNS to charge separate water to create a tremendous amount of electrons to power the system. In this illustration, electrons act as a canvas does in a painting: sunlight is the paint, and electrons are the brushes.

SUMMARY

BLUE LIGHT IS A STIMULANT THAT CREATES ROS/RNS NORMALLY

And stimulants are 👍 great. Most Americans drink a few cups of stimulants each morning ☕️ to get themselves up to face the daily grind.

But you know what’s not great? Being stimulated 24 hours of every day by blue light. This ruins the dose-response curve of the ROS/RNS. That is exactly what is occurring to modern humans because they live indoors and use tech screens excessively. What else is different about this version of blue light? The blue light that wakes us up in the sun is NEVER present without 42% IR-A light, which is red.  AM sunlight has 42% red light and only 1600K of blue light. This small stimulus of blue light is about to improve executive function of the prefrontal cortex. This blue light needs red light to control the oxidation ROS/RNS that blue light makes when present without red light in our light environment.

ALL CELLS contain ion channels in their outer (plasma) and inner (organelle) membranes. Ion channels, similar to other proteins, are targets of oxidative impact, which modulates ion fluxes across membranes. Subsequently, these ion currents affect electrical excitability, such as action potential discharge (in neurons, muscle, and receptor cells), alteration of the membrane resting potential, synaptic transmission, hormone secretion, muscle contraction, or coordination of the cell cycle.  Circadian biology controls all of this.

An important class of ion channels is the family of potassium (K+) channels (in the nitric oxide cycle); they are not only in charge of the membrane resting potential or the repolarization of the action potentials but also control cell proliferation or transmitter/hormone release, to name a few. A subgroup of K+ channels are the so-called calcium (Ca2+) activated K+ channels, which need either an increase of Ca2+ at their intracellular face to open or a combination of Ca2+ and voltage to function correctly. Maxi Ca2+-activated K+ channels, also named BK channels, constitute a subgroup of Ca2+-activated K+ channels.

Do you know where these ion channels exist in humans?  They are found on the inner mitochondrial membrane. EXCESSIVE BLUE LIGHT exposure destroys these potassium ion channels to ruin signaling of cells that control the circadian mechanism and are associated with leptin and melanopsin. LET THAT SINK IN with all the ways modification happens on the C and N terminus of proteins.  I only shared a couple with you in this blog.  

Mitochondria are a significant source of ROS generation targeting BK channels. Blue light creates that stimulus when RED LIGHT IS ABSENT.

The inner membrane of mitochondria contains BK channels (mtBK), which appear essential in the production of ROS. mtBK channels appear to be inserted into the mitochondrial membrane with the toxin binding sites for charybdotoxin and iberiotoxin exposed to the mitochondrial intermembrane space. This can be accessed using outside-out patch configuration of the inner mitochondrial membrane. Consequently, the C-terminal tail domain, including the Ca2+ binding site, is localized to the mitochondrial matrix where the proton gradient exists. 

RED LIGHT MOVES PROTONS BEST. Blue light creates the most ROS. Do you understand why subtracting red and UV light from blue creates mitochondrial diseases now?

Can you imagine what the centralized chemists controlled by Big Pharma may find when they look at C and N terminus modifications by light frequencies in POMC or DHA in humans?

CITES

1. Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol. 2009;9(11):799–809.View this article via: PubMed CrossRef Google Scholar

2. van der Flier LG, Clevers H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu Rev Physiol. 2009;71:241–260.  View this article via: PubMed CrossRef Google Scholar

3. Watson AJ, Duckworth CA, Guan Y, Montrose MH. Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function. Ann N Y Acad Sci. 2009;1165:135–142.

4. Long J.Z., Svensson K.J, Bateman L.A., Lin H., Kamenecka T., Lokurkar I.A. et al.  The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria. Cell. 2016; 166: 424-435

5. https://www.cell.com/cell-chemical-biology/abstract/S2451-9456(20)30146-X

6. https://pubmed.ncbi.nlm.nih.gov/26365347/

7. https://pubmed.ncbi.nlm.nih.gov/20136843/

QUANTUM ENGINEERING #59: TETRAGRAMMATON PART 3: WHY DOES LIFE REFLECT A RED EDGE?

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Centralized researchers say the processes behind the solar tracking are an unexpected mystery.  Maybe if the knew the evolutionary history of flowers better they’d know about the history of the non visual photo receptive system?

Phototropins of plants and melanopsin or mammals have a lot in common.  They are the blue light non visual photopigments.  Auxin of plants and encephalopsin have a lot in common.  I wrote about auxins in the Ubiquitination series years ago.  What protects the nucleus from UV light in mammals? OPN3 = encephalopsin

Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation​ in mammals.  Opsins work with auxins too.  Amazing Mother Nature reuses her best ideas huh?.  Why don’t the scientists know?  Because centralized science is done in silos.

The ancestors of flowering plants diverged from the common ancestor of all living gymnosperms before the end of the Carboniferous, over 300 million years ago. This is when mammals showed up on Earth as well and began to specialize in melanin biology and used opsins to expand its usefulness on Earth with a changing sun after the Cambrian explosion.  In the Cretaceous epoch, angiosperms diversified explosively, becoming the dominant group of plants across the planet to create flowers.  Without non visual photochemicals there is no flowering plants.

What do decentralized clinicians and scientists know?   Light energy is known to mediate isomerization through several mechanisms, including thermal, photochemical, and mechanical effects. Photoactive molecules are often isomerized by photochemical action as they can directly absorb light exciting the molecules to an upper electronic state. In photoisomerization events, the photon energy of the electromagnetic radiation often causes the rearrangement of cis-trans positions of organic compounds that contain a double bond in their structure.  See retinal transformation as a best in class example of this chemical process on Earth.

Decentralized medicine lesson:  Earth’s atmosphere has not always contained significant amounts of oxygen. For the first two billion years of our planet’s history, the atmosphere was rich in carbon dioxide and methane, but around 2.4 billion years ago something changed: the Great Oxygenation Event that saw the abundance of free oxygen in our atmosphere dramatically rise. The cause of this is thought to be cyanobacteria, which are able to perform photosynthesis – the transformation of sunlight and carbon dioxide into metabolic energy to produce sugars that fuel life’s processes, and oxygen as a ‘waste’ product – using a green pigment called chlorophyll.  I covered this in the Rubin/Kruse/Huberman Part 1 & Part 2 podcast.

I told Andrew that retinal predated chlorophyll, hemoglobin, and melanin, and that the retinal and chlorophyll evolved in tandem, absorbing sunlight at complementary wavelengths.  That is biophysics 101.

Retinal-based phototrophic metabolisms are still prevalent throughout the world today, especially in the oceans where life began, and represent one of the most important bioenergetic processes on Earth.  Recall that Andrew was surprised that mammalian brains where filled with amphibian melanopsin in the podcast, but I was not.  I know the evolutionary history of the chemical evolution of light absorbing pigments.

Chlorophyll absorbs light peaking at wavelengths of 465nm and 665nm. This is why leaves appear green, because they reflect green light rather than absorb it. However, the Sun’s spectrum peaks at ~550nm, which includes yellow and green light.

A number of proteins that absorb sunlight contain a molecule of retinal, including one protein called bacteriorhodopsin that absorbs light peaking at 568nm, close to the wavelength at which the Sun’s light peaks, and most notably in the range that chlorophyll does not absorb in. This is exactly what should have gotten centralized science thinking that the two pigments – retinal and chlorophyll – co-evolved on early Earth before the sun emitted its increase burst of UV light around the Cambrian explosion.

Remember I told them both our sun is a G class star and I reminded them both of the implications of a changing light perspective?  I retold this story to Bill Gifford in Part three of this podcast that has not yet been released.  Here you are getting an early preview of that interview.  I have argued for 15 years that because retinal is the simpler molecule and linked to every opsin found in mammals, it would have come first, with chlorophyll (which is more efficient at transforming sunlight into metabolic energy) evolving afterwards, with each filling different niches in terms of the light they absorb.  This is why the biology of Vitamin A and Vitamin D are linked in mammals.

Experiments have now shown that combining bacteriorhodopsin with a membrane vesicle to form the equivalent of a biological proto-cell can effectively result in trapping and storing sunlight in a cell.

It should have made sense to centralized scientists that this was a very early evolutionary invention coinciding with the evolution of the first cells, but it was not because centralized biology does not understand how light sculpts life.

Today, in the lab, we now have proof my hunches years ago were correct.  Using the energy-trapping capability of the cell membrane, the membrane potential [the difference in electrical potential between inside and outside the cell, allowing the cell to provide energy] represents one of the most important reasons why cells are the fundamental unit of life.

Because vegetation on Earth predominantly absorbs red light, but reflects infrared light, viewing vegetation using a spectroscope reveals a dramatic dip in reflected light at red wavelengths, a sudden decrease that is called the ‘red edge’. More complex animal life, like mammals also absorbs red light, but it is also absorbs infrared light as well.  This gave animals more complexity at the same time in evolution.  In plants, it has been shown today in NASA experiments that when probing the spectrum of light reflected from potentially habitable exoplanets, scientists could search for a red edge in the planet’s light, which would be a biosignature indicative of vegetation using chlorophyll, or its extraterrestrial equivalent.  This red edge also explains why the picture below is axiomatically true and why you must question your centralized eye doctors.

SUMMARY

I’m back in NYC right now and am visiting the place where I figured this out as a youngster.  Today I am back at the Hayden Planetarium on the West side of Central Park with all the leaves changing color because of a changing light cycle.  When light changes it induces a light stress in the plant.  This is seen by us a color change in leaves.  Similarly, when mammals are stressed by light they exhibit a blue shift in their non visual photoreceptive system.  This has huge implications fro decentralized clinicians learning how to care for their patients in the new paradigm of medicine I am bringing to the government of El Salvador.

In Malibu and again on stage in Lisbon Portugal I made the case that the mRNA vaccines gave humans who were compliant with the vaccine mandate blue shifted.  When their tissues were blue shifted, the non visual photoreceptors were damaged, retinal was released, and photonic signal was changed and this lead to sudden and new complications in our clinics.  I knew to expect this in March of 2020 and this is why I told my tribe to avoid these new genetic therapies.

How did I figure this out as a kid?  My time at the Hayden Plantetarium as a kid was critical in answering this mystery.  I was curious about light and how the sun changed over eolutionary timescales and remember that I was taught in grade school sunflowers use retinal in them.  I then engaged my curioity further and I found out that retinal absorbs what green plants reflect back to the environment.  This is why all plant life looks green to the mammalian eye.  This is another perfectly couple system in biology on Earth that links absorption and emission spectra of light.

Intriguingly, since retinal pigments in the mammalian eye and in the non visual photosystems absorb green and yellow light, and reflect or transmit red and blue light, then retinal-based life, early on Earth would have appeared purple in color if humans were on Earth to see it.

THE COLOR PURPLE SOLVED THE MYSTERY

Proteobacteria are the oldest bacteria on Earth in our evolutionary history. They are a purple bacteria.  Proteobacteria are the dominant prokaryotes in aquatic systems. The ocean is where life begain.  The Proteobacteria lineage contains phototrophs, chemolithotrophs, and chemoorganotrophs, and its members can be found in both oxic and anoxic environments.

This explained to me why they were the dominant form of life on Earth before the Great Oxygenation event.

Since retinal (Vitamin A) is a much simpler molecule than chlorophyll, I reasoned, it could and should be more commonly found in life in the Universe, and therefore a ‘green edge’ in a planet’s spectrum potentially should be viewed as a biosignature for retinal-based life.  It turns out now NASA agrees with Uncle Jack too.  They always look for the green reflected edge of planets spectra now when they are looking for life in the cosmos.  The non visual photoreceptor system is a key in the development of the melanin in the mammalian system on Earth.  Chalk one up for decentralized science over the centralized opinions.

NOW YOU SHOULD UNDERSTAND WHY ALL THESE PICTURES I HAVE USED FOR YEARS WHERE WAY AHEAD OF THEIR TIME.

CITES

1. https://www.theguardian.com/science/2023/oct/31/seeds-of-doubt-mystery-remains-over-how-sunflowers-track-light

2. https://www.cambridge.org/core/journals/international-journal-of-astrobiology/article/early-evolution-of-purple-retinal-pigments-on-earth-and-implications-for-exoplanet-biosignatures/63A1AD8AF544BEEF4C6D4A2D53130327

QUANTUM ENGINEERING #58: TETRAGRAMMATON PART 3 = HUMAN REGENERATION DRIVEN BY MELANIN

I was just out in Malibu with Mr. Rubin and one of his friends, interviewing me for a movie we are making about me and Quantum Biology.  We sat down two days ago and did a three-hour podcast that will be part 3 of the Tetragrammaton series.  The goal of part 3 is to go deeper into the implications of what was said between Rick, Huberman, and me. Part 3 was done without Andrew.  Bill Gifford sat in his place, and he is an award-winning health journalist.

SO WHAT DID WE TALK ABOUT?

Can we see the evidence of light toxicity in the skin before it afflicts the brain?  Yes, we can.  People often forget that the skin and brain come from the same tissue layers in the human embryo.  Because of this linkage, your skin and your eyes tell your decentralized physician to look deeper into your health to see how badly you are afflicted with light toxicity.  See this thread and read my comments for the details.   HYPERLINK

Do you know the implications of the last post above about breast cancer and Vitamin D and sulfation? What happens when you add sunlight to a skin? Melanin becomes eumelanin because of the addition of the sun. Did your experts know that? Did you see the color of all human hair, skin, and eyes is made from this sulfated semiconductor? Do your experts know how this all works in the human mammal? I’m just warming up, folks.

What makes melanins so unique and so attractive to science these days?

The list of arguments is a long one. From the viewpoint of physicochemical properties, all melanins share:

(a) a broadband absorption spanning the entire spectral range of the visible domain

(b) a permanent electron paramagnetic resonance (EPR)d signal denoting a stable paramagnetic character.

An unpaired electron can change its electron spin by either absorbing or emitting a photon of energy, denoted by hv, such that the resonance condition, hv = the change in Energy is obeyed. This leads to the fundamental equation of EPR spectroscopy.

Electron Paramagnetic Resonance (EPR) is the study of direct transitions between the electronic Zeeman levels of the ground state. EPR is a magnetic resonance method under suitable microwave stimulation, enabling the unpaired electrons by their magnetic moment.  The basic concepts of EPR are analogous to those of nuclear magnetic resonance (NMR), but the spins excited are those of the electrons instead of the atomic nuclei.

(c) hydration-dependent semiconductor-like behavior.  For example, eumelanin conductivity increases in water because it conducts electricity via ions and electrons.

(d) efficient dissipation of electromagnetic energy as heat.  Melanins can absorb massive amounts of light and get rid of it quickly without damage to the system.  Water with a high dielectric constant helps facilitate this.

On the chemical side, most melanins display:

(a) antioxidant properties, both as an H-atom donor and as a reducing agent;

(b) metal chelation and binding of organic compounds

(c) redox behavior.

In addition, melanins are bioavailable, biocompatible, and biodegradable, thus representing the most promising candidates for biomedical applications in optical signaling in the condensed matter physics world of science.

Melanin has many of the same semiconductive abilities we see in cytochrome c oxidase, which is also a semiconductive protein (above).  That protein is responsible for water creation in the mitochondrial matrix. Water creation and alteration by the mitochondrial matrix is how the DC electric current is stepped down to the precise amperage to create the regenerative drafts used in mammalian tissue regeneration found by Robert O. Becker’s experiments..

Melanin is the critical tissue in all mammals. It allows for tissue engineering and regeneration via nanotechnology operations in the cell via a combined diagnosis and therapy (theranostics) action with our stem cell supply. Melanins are also critical in creating the bio-photon spectrum needed to run the specificity of biomolecules in the cellular system of control. The source of the electromagnetic wave spectrum has to match the absorption spectra of biomolecules to keep the system far from equilibrium so coherence and entanglement are possible.

WHAT IS INFLAMMATION IN THE MAMMALS FUNDAMENTALLY?

It is from a lack of sun or too much light at night.  This is the primary decentralized cycle in all of biology.

Eumelanin is a form of melanin and conducts electricity – albeit weakly – in its natural state. Researchers first discovered that the polyindolic pigment was a semiconductor in the 1970sand suggested that this behavior comes from energy bands associated with a non-localized empty molecular orbital within the eumelanin polymer chain.  All free radicals are paramagnetic because they have unpaired electrons. So are all the melanins in mammals.  This makes them the ideal wide band gapped (WBG) semiconductor to absorb them.  This again points out how modern biology is lost in the woods.  They believe ROS/RNS is terrible when, in fact, they are critical in how non-linear optical signaling controls biochemistry in cells by creating the right spectrum in bio-photon release from tissue-level metabolism controlled by mitochondria.  When melanin is missing, chaos in tissues is created = inflammation.  That is how inflammation manifests in you and every mammal on this planet.  This is how modern neolithic disease is being made in the USA at alarming rates.

So, my patrons, I hope you are beginning to see why Nature wants to limit deuterium in the mitochondrial matrix now.  Could its carburetor function be linked to water chemistry that is quantized to the amount and spectral density of biophoton release in the matrix by metabolism?

I think so.

A lack of POMC, degraded melanin, and a matrix not making water is all a sign of a mammal in deep need of the sun to begin its melanin renovation Rx.

Well, it turns out that deuterium in the mitochondrial matrix is controlled differently in every body tissue because each tissue needs a specific regenerative current to differentiate stem cells to rebuild tissues anew.

The reason is simple: deuterium concentration allowed into the mitochondrial matrix is how a cell controls metabolic rates in different tissues. No two tissues have the same physiology.  Therefore, metabolic rates have to vary in these tissues to be thermodynamically efficient.  This creates the spectrum of the VUV-IR-A light used to manage the biochemistry in that specific tissue.   Not all tissues have the same metabolic rates because of their physiologic needs. This means the metabolism of a mitochondrion produces its unique spectra.  A unique spectrum means the matter in these tissues must also have individual absorption spectra.  This should raise the question, how does the matrix in differing tissues get more deuterium? What type of WBG semiconductors should we expect there?  What is the gating mechanism?

The answer is the type of melanin adjacent to the uncoupling proteins of mitochondria that generate heat from metabolism.  Remember, all haplotypes produce varying amounts of heat via uncoupling efficiency.   The thermodynamics here are also linked to how badly degraded the melanin is in the tissue system.  A big clue to this mystery is if ROS/RNS production is driving biomolecules of inflammation higher or lower:  HS CRP, haptoglobin, homocysteine, lowered glutathione, procalcitonin, etc.  This heat is liberated into the surrounding water to dampen the current in the electrical conduction pathways found in cells.

The recently released Owen Sheasby podcast illuminated this effect.

The further one goes from the equator; the more uncoupling humans need to use to control the regeneration current in a tight ampere range. Equatorial light is the most powerful light on Earth, and this is the light human mammals evolved under.  That system is a powerful melanin stimulus for the skin.  At higher latitudes, cold temperatures stimulate more robust frequency endogenous light generation.   Moreover, as a result, more heat is produced, and melanin in our interiors becomes a better electrical conductor.  Any excess heat is thermalized directly to water so the system can remain far from equilibrium.   The slide at the beginning of this blog post shows this effect.

The closer the equator one lives, the less uncoupling one needs because the sun provides all the ingredients for self-regulated autophagy and apoptosis, which is controlled by ferroelectric currents in the cell that are dampened by melanin biology. Why is ferroelectricity the key to this process?

Iron’s toxicity is mediated by sunlight, and few people seem aware of it. Please recall the first steps of heme synthesis in mammals begin in the mitochondria.  This was proven by papers from Simcox JA, Mitchell TC, Gao Y, et al.  In Rubin, Kruse, Huberman Part 1 & @ I told you hemoglobin was the second big innovation in evolution after chlorophyll.

Heme synthesis begins its first step in mitochondria. If you have a circadian mismatch disease tied to melanopsin dysfunction by definition you are blue light toxic or nnEMF toxic and this causes a defect in mitophagy and ruins the iron cycle in humans. This immediately affects the liver clocks, too.   This leads to fatty liver disease.

People in centralized healthcare often forget heme synthesis occurs partly in the mitochondria and partly in the cytoplasm. This is precisely how the TCA and urea cycle are built in us too. The process begins in the mitochondria because one of the precursors is found only there. Since this reaction is regulated in part by the concentration of heme, the final step (which produces the heme) is also mitochondrial.

People with defects in iron always have a blood dyscrasia (anemia) at some level and it usually bleeds into fertility and thyroid hormone creation too, because of its link to AM sunlight deficiency. These pathways are proximal to the melanin-building pathways as the slide shows below.  In Part 3, I get into it with Bill about how melanin degradation and bleeds backward into this pathway via hypoxia.  This is a catabolic effect  All nnEMF cause hypoxia in humans and drives this catabolism of endogenous melanin to lead to interior destruction and a lack of wound healing.

Remember, purple light = UV light and it creates oxygen in our venous blood and this drives anabolic pathways to make melanin via POMC and alpha MSH.

Purple light in sunlight ALSO stimulates RBC synthesis in humans. Blue light causes RBCs to break down sooner and live a shorter life than they can. What is the color of the main breakdown color of heme? It is the complementary yellow color of bilirubin. Yellow is the complement of purple, and orange is the complement of blue in the color wheel.

An analogy to explain this idea is how paragliders use the thermals on Mount Blanc to ride high up into the atmosphere. The sun heats the air at the mountain’s base, and the heat rises to carry the gliders to very high altitudes.  This allows them to ride the thermals almost at no energy cost. The only price needed is the solar input that drives the temperature variations. If you were a glider who wanted to go further than anyone else has ever gone, you’d need to add an engine to your back that could work to power a fan to move you further. If you did this, you’d have to have a solution for the altitude problem. Why? As we go higher, oxygen is not as expected, and neither is temperature.  This is why the circadian mechanism measures them in their optical lattice clock mechanism. I explained this to Mr. Sheasby in his podcast and the Tetragrammaton part 3 podcast.   This is why the human retina consumes more oxygen than any tissue in the human body.  Modern eye researchers and clinicians do not explain why the choriocapillaris does what it does.  I realized it immediately as the source of why obesity happens when the periphery of the retina is destroyed by blue light.  This also occurs when melanopsin is at its highest density in human tissues. The choroid sits adjacent to the retinal pigmentum epithelium on its densely fenestrated side to act like a radiator to absorb heat. A thickening of the choroid is the first sign of impending obesity in humans (Pics below).  BOOM

This also explains why fat people now have lousy bones and why the mechanical stress of weight no longer makes Wolf’s law factual in centralized biology.

Metabolomics network studies show that the kinetic isotope effect (KIE) of deuterium affects the metabolism of L-lysine, L-glutamine, and L-serine.  This is why linoleic acid loaded with deuterium affects bone metabolism at its core.  Pass that fact on to the food gurus.  They remain ignorant of biophysics.  Be careful who packs your parachute, folks.

As such, you’d need a mechanism to alter the fuel and oxygen mix to be oxidized to power your flight. This is very similar to what a car has to do with its carburetor. The higher you go, the more pseudohypoxic you get, so you must alter the fuel source to maintain your flight.  The third through fifth citations below highlight this.

Mitochondria are hydrogen-fueled engines, so deuterium concentration and production is critical in biology.  This explains the title of this paper.  Deuterium-depleted water stimulates GLUT4 translocation in the presence of insulin, which leads to decreased blood glucose concentration​.  I still chuckle at the food gurus ranting about seed oils and never realizing they are deuterium bombs.  https://pubmed.ncbi.nlm.nih.gov/34510301/

The UCP-2 proteins were innovated for this reason. It controls the fuel-oxygen mix in mitochondria. It is a carburator for deuterium/H+ flow. The more deuterium that flows in, the more anions in the TCA cycle are bound to the substrates because of the kinetic isotope effect (KIE) of deuterium. One deuteron binds 96 H+ protons in the matrix.  This slows the spin rate of the TCA cycle. That has an indirect effect of raising and lowering methionine in its metabolic cycle, causing a collection of heavy metals.  This is how melanin detoxes heavy metals and does not use endogenous glutathione.  When someone has heavy metal toxicity, it is a sign to me, as a decentralized clinician, that they have a vast POMC problem and they need more sunlight to renovate melanin inside the affected tissue.  Chelating with exogenous agents is a losing strategy of functional medicine.  The reason it’s so popular is because of the revenue it generates.

SUMMARY

How do you know your clinician is genuinely a decentralized mitochondriac? The whole world will tell you they are nuts, and you should not follow what they tell you. Be wise enough to know that the paradigm does not like truth-tellers. They are bad for business.

Is melanin a perovskite material with unique biophysical abilities that centralized biology has ignored at your peril?  You bet your ass it is.   What else doesn’t centralized science know?  Biophysics controls all the biochemistry in their books.  If you do not understand what light is doing you don’t understand decentralized biochemistry either.  They are light ignorant.    Biomacromolecular pigments, such as melanin, play an essential role in the survival of all living beings as I told Rick and Andrew. Melanin absorbs sunlight transforms it into heat and deposits the energy in water and proteins at the electronic level to build a dissipative system.  This step is crucial for avoiding damage to skin cells. Light absorption produces excited electrons, which could either fall back to ground states by releasing the heat (photothermal effect) and/or light (photoluminescence), or stay at higher energy levels within its lifetime period, which can be captured through external electronic circuitry (photovoltaic effect).   In published studies that no one in centralized biology reads, it has been demonstrated that the combination of melanin with halide perovskite light absorber in the form of a composite exhibits high absorbance from the UV to NIR region in the solar spectrum. And the hybrid displays significantly reduced photoluminescence and minimized density of residual excited states (verified by photovoltaic measurement) owing to the enhanced considerably nonradiant quenching by the melanin.

As a result, the composite shows an ultrahigh solar-thermal quantum yield of 99.56% and solar-thermal conversion efficiency of ≈81% under one-sun illumination (AM1.5), which is superior to typical carbon materials such as graphene (≈70%). By coating the photothermal composite film on the hot side of thermoelectric devices, a 7000% increase in output power as compared to the blank device under illumination is observed.   Mammals are experts in collecting the sun using this technology woven into the fabric of NATURE.  Get your skin in the game of the sun.

HYPERLINK

Please remember blue light induces hypoxia in cells, and this stimulus causes melanin to break down into L-DOPA, dopamine, adrenalin, and noradrenaline.   Every biochemistry textbook printed has this pathway, but most centralized PhDs and clinicians have no idea how it links to melanin biology.  How much crowd wisdom is there when most of the crowd is afflicted by nnEMF and blue light, and their frontal lobes have been emptied of melanin/L-DOPA/dopamine anyway?

Did you know that cephalopod ink is 70% pure melanin?  Do you know why?  https://www.youtube.com/watch?v=ohZsX5-qAD0

More sun = more water production by the mitochondrial matrix = more mitochondrial melatonin production = less chance of leptin resistance = less chance of neolithic disease.  Any light at night causes leptin resistance = Blue light at night is the worst offender = because it makes melatonin vanish = causing leptin resistance = mitochondriac, and melanopsin wisdom and proves the food guru fail……

LIGHT’S EFFECT > FOOD EFFECT

All food is, at its core is matter created downstream from sunlight—photosynthesis wisdom on display.    When the world moves away from your biological necessities, becoming fearful is fruitless. That’s not the point, given the dire situation. It’s learning how to control your fear, harness it, and use it as fuel to change your conditions of existence. Fear shouldn’t shut us down; it should wake us up to increase the fidelity of our awareness and focus to overcome the present challenge we face and crush it.

Stand for what is right even if you are standing alone. There is a fine line between challenging yourself and overwhelming yourself. Changing paradigms is not for the weak of heart or mind. This type of transformation takes hold of you. Invades you. Soon it owns you. You want to be free of them, but you never will be. A prolonged movement on the right way is better than overwhelming speed on the wrong path, and this is why you enjoy the chaos of being overwhelmed. You must become the change you seek in this world now.

Part 3 of Tetragrammaton is epic.  I hope you all enjoy it once Mr. Rubin is done editing it.

HAPPY HALLOWEEN!

CITES

1. Pullman, A., and Pullman, B. (1961). The band structure of melanins. Biochim. Biophys. Acta. 54, 384–385. doi: 10.1016/0006-3002(61)90389-4

2. https://www.popsci.com/eumelanin-conduct-electricity/

3. https://www.sciencedirect.com/science/article/abs/pii/S0166432821004861

4. https://www.frontiersin.org/articles/10.3389/fendo.2022.927576/full

5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881424/

6. https://twitter.com/DrJackKruse/status/1718950743674163200

QUANTUM ENGINEERING #57: WHY I DOUBT EINSTEIN

Schwarzschild’s equation is used to calculate radiative transfers.  These are energy transfers that occur via electromagnetic radiation through any medium in local thermodynamic equilibrium that both absorbs and emits light radiation.

The general theory of relativity states that in particular, the curvature of spacetime is directly related to the energy and momentum of whatever matter and radiation are present.

Einstein’s general theory of relativity can be summed up in just 12 words:

Space-time tells matter how to move; matter tells space-time how to curve.

This also implies that light energy responds to the action of matter.

The Schwarzschild equation and the Schwarzschild radius are related concepts in the theory of general relativity, which describes how gravity affects space and time. The Schwarzschild equation is a mathematical solution to the Einstein field equations, which describe how the curvature of space-time depends on the distribution of mass and energy. Noether’s theorem solves the energy requirements of the bending of space and time.

I actually talked about that here in this podcast but I think few people really understood where Uncle Jack was driving you.

Many smoothed brain thinkers believe everything is just about energy with respect to the mass equivalence equation.  They do this because they have a rudimentary understanding that equation.  This concept offers us nothing, as I’ll explain below.

WHY THE OWEN SHEASBY PODCAST NOT YET RELEASED WILL MATTER DEEPLY TO THOSE WHO REMAIN IN THE DARK

If you consider the mass-energy equivalence relationship, E= mc^2 you might be led to this conclusion. However, what this equation really tells us is that matter is not conserved in Nature.  It is a shocking because it tells us that mass can be converted to energy.  It does say how but Nature allows for it.  In other words, E=mc^2 tells us something deep about mass that has huge implications for biology. That’s why it’s useful to the mitochondriac. However the concept that everything is just energy gets us nowhere in terms of understanding our world. It is essentially a statement of existence. The fact that the universe exists and is full of energy is an empirical fact. It is not explained by the concept of energy. Similarly, the laws of physics are ultimately empirical, and they are also not explained by energy. Energy is essentially an accounting tool that helps us solve problems. This is what leptin is in biology.  Melanin however, is a lot like Noether’s theorem.  It tells us a lot about the mass in the system and how much light can be absorbed into the system. The physics is given in the nature and character of the fundamental forces that describe how things interact.

Life is basically about electricity and magnetism that come from light in a system. Think about the tests done by your centralized doctor in the form of an EKG, EEG, and an EMG. All show the electrical and magnetic potential of our organ systems. Anything and everything electrical stems from the phenomena of charge. No one seems to have a clue why this relationship in nature exists, but physics tells us it is true. Atoms are made up of 3 parts: Protons have a positive charge, neutrons are neutral, and electrons have a negative charge. Here is the interesting part: Electrons have the equal and opposite charge of protons, but an electrons atomic mass is 1/1836th that of a proton.   This is a huge difference in mass.  Thusly, charge of these particles is the main variable with respect to their atomic mass. Atomic mass links to the thermodynamics and energy needed in the system because mass determines the size and shape in protein lattices. The charge of the lattice is determined by the protons and electrons in the system.  Electrons delocalize most often because they are not encumbered by the mass as protons are.  This points out why deuterium is a problem in mitochondrial biology.  The mass of the lattice determines the how the speed of light can travel in our tissues.  It also determines the frequency of light emitted.  This is the basis of how a semiconductor emits light = LED.

The speed of light is variable in a substance when it becomes encumbered by electrons.  This is why size and shape alter the thermodynamics of things made up of electrons and protons.  Light only interacts with electrons via the photoelectric effect.  Thusly, electrons are exicted and powered up by light.  Light instantaneously interacts with matter to create the fastest pathway through tissues.  This directly links tissues to Fermat’s principle.  Light does not interact with protons or neutrons and has to go around them.  This increases the distance that light must travel and it creates tiny delay’s in tissues at the quantum level.  Just because the distance increases does not mean the path is longer in all cases.  That small delay creates a signal that denotes biologic time in a cell.  That delay is observed in the telomere length of a cell.  What moves atoms or things made up of atoms?  Light is capable of this fundamental task and nothing else can.

How light is captured and travels in our tissues is how time manifests in biology = melanin biology.

On the flip side; energy and momentum are quantities that will crop up in the analysis of virtually all physical systems that exhibit such symmetries.  Noether’s theorem says that every symmetry implies a conservation law is present and acting and that link is always to energy in the system in question.

For mammals, melanin controls that process.

THE PICTURE STORY ABOVE SHOWS YOU CENTRALIZED SCIENCE STILL HAS NO IDEA HOW FAR AHEAD MY MEMBERS ARE IN THE STORY OF LIGHT AND MAMMALS.

Understanding the physics of organisms is the only way to resolve this chasm in knowledge.  

Light has a universal speed limit at 186,000 miles an hour in space where matter is sparse compared to space-time.  Inside a cell matter is not sparse. Light travels 30 centimeters in one nano-second. The only way to increase its energy/power is to increase its frequency and this is why endogneous light production is a key feature improvement in mammals. That change in energy can alter the electric and magnetic fields associated with the atomic lattice present in cells where matter is present. When those fields are altered, so are the interactions that can occur with specific light frequencies. The frequency of light determines the current and the force of the current. The DC current is what determines wakefulness and sleep.  Current is the flow of electrons or protons inside the matter of cells and is measured in amperes.  During daytime the DC current is present and at night it is absent in the brain when we sleep.

Magnetic fields are produced by the motion of electrical charges inside of tissues.  A fundamental property of magnetic fields is that they exert forces on moving electrical charges.  Magnetism is best seen in cells by the free radicals they create as they move electrical charges inside of cells.

Magnetism outside of cells is best visualized by putting a magnet under a paper and throwing iron filings on the paper. You can see the field the magnet generates by looking at the pattern of the iron filings. If you throw away the filings and add new iron filings the exact same pattern will emerge showing you that the magnet, and not the atoms of iron, determine the shape of the field of action.  This action is very similar to what the human body undergoes every night and day cycle.  Its molecules are disturbed by daylight constantly and are condensed back to their form at night.  Sunlight alters, disturbs, and un-condenses magnetic fields. Sometimes atoms in us are lost and we have to replace them from our environment.  We get a fresh supply of atoms from water, food, and from light. But thanks to the controlling forces within our cells, namely our mitochondrial electric and magnetic fields, new molecules and cells are rebuilt as before and arrange themselves in the same pattern as old atoms were.  They are recycled by autophagy and apoptosis in our colonies of mitochondria.

Current has another feature called electromotive force. This is the “push” behind the current and it is measured in volts. Currents in space flow differently than they do on Earth. This is a function of the plasma they exist in. Plasma is one of the four fundamental states of matter, the others being solid, liquid, and gas. A plasma has properties unlike those of the other states of matter. Plasma in space can travel multi-directionally.  Plasma’s inside the ionosphere can only flow unidirectionally.  The presence of a significant number of charge carriers makes plasma electrically conductive so that it responds strongly to electromagnetic fields. Like gas, plasma does not have a definite shape or a definite volume unless enclosed in a container or contained by an environment. Unlike gas, under the influence of a magnetic field, it may form structures such as filaments, beams and double layers. In space, current flows in all directions because space is essentially a vacuum filled with double layered plasmas.  The ionosphere itself is a plasma.  Sunlight must traverse that plasma to get to mammals.

On Earth, within the ionosphere where life exists, energy flows unidirectionally from the sun to the surface of the Earth.  This flow controls the quantum yield of photosynthesis which forms the basis of the food webs on Earth.   Current only flows when a source of electrons is connected to a conductor that contains fewer electrons.  This is why lightening (another plasma) flows from clouds to the Earth’s surface and not into space. This allows flow from things with a higher electron density to one with a lower density of electrons. If there is no conductor present between these density changes in electrons, there is only a hypothetical charge of flow we call the electric potential.  That potential is measured in volts.

An electric field forms around any electric charge and we can now imagine them with unrivaled precision.  That implies that any other charged object if it has an opposite polarity, will be attracted. If the charge is similar they will be repelled. The charge differentially is reflected in the distance between the two densities. The distance between to charged particles is called an electric field. The field is the region of the space of this plasma in which an electric charge can be measured. This is measured in volts per unit of area. All electric fields are associated with magnetic field actions by Maxwell’s laws. We can distinguish electric fields from magnetic ones easily today.  This was not true in our recent past.

Charge is poorly understood by most people. Understanding of magnetism, by most, is atrocious. Magnetism is an intrinsic property of atoms that manifests in two polarities. Any flow of electrons is accompanied by a combined electric and magnetic field around the current of flow of electrons. Those two fields are always at 90-degree angles to one another. As electrons flow, they disturb other electrons around them in these fields.  Just as a current produces a magnetic field, a magnetic, when it moves in relation to a conductor, induces a current. Magnetic fields are measured in Gauss.  Both fields are determined by lines of force and they indicate the direction and shape of the field locally between particles. Both fields power declines with distance but their influence over charged particles is infinite.

SUMMARY

General relativity has acquired a reputation in centralized scinece as a theory of extraordinary beauty.  Why?  Subrahmanyan Chandrasekhar has noted that at multiple levels, general relativity exhibits what Francis Bacon has termed a “strangeness in the proportion” (i.e. elements that excite wonderment and surprise). It juxtaposes fundamental concepts (space and time versus matter and motion) which had previously been considered as entirely independent. Chandrasekhar also noted that Einstein’s only guides in his search for an exact theory were the principle of equivalence and his sense that a proper description of gravity should be geometrical at its basis, so that there was an “element of revelation” in the manner in which Einstein arrived at his theory just by thinking about the Universe.  Other elements of beauty associated with the general theory of relativity are its simplicity and symmetry, the manner in which it incorporates invariance and unification, and its perfect logical consistency.  But there is a problem.

Reconciliation of general relativity with the laws of quantum physics remains a huge problem in modern science.  As a mitochondriac you must hold open the idea that Einstein is wrong in some of his assumptions.  Why?  Mother Nature operates quantum mechanicallly 100% of the time.  I trust her more than Sir Albert.  Not only that, Einstein also doubted his own work when he introduced the cosmological constant.

Quantum mechanics is the science of probabilities, biology is the study of the improbable which only makes sense from the perspective that the living state is only probable using reactions that appear statistically improbable.  The power in that sentence is immense and highlights the difference in understanding between the decentralized and centralized science.

WHY DON’T I TRUST A SCIENTIST I REVERE?

He is centralized in his ideas.

You should know that the Einstein field equations are nonlinear and are very difficult to solve. Einstein used approximation methods in working out initial predictions of the theory. But in 1916, the astrophysicist Karl Schwarzschild found the first non-trivial exact solution to the Einstein field equations.  This was called the Schwarzschild metric.

This solution laid the groundwork for the description of the final stages of gravitational collapse, and the objects known today as black holes. In the same year, the first steps towards generalizing Schwarzschild’s solution to electrically charged objects were taken, eventually resulting in the Reissner–Nordström solution, which is now associated with electrically charged black holes.   In 1965 -75 Einstein’s predictions in general relativity were proven again correct when quasar black holes were found to exist in nature.  This tells us his theory has deep predictive value, but it still does not jive with quantum mechanics…….the science of biology.

In 1917, Einstein applied his general theory of relativity to the universe as a whole, initiating the field of relativistic cosmology. This is where I think he went off the rails.  In line with contemporary thinking, he assumed a static universe, adding a new parameter to his original field equations—the cosmological constant—to match that observational presumption.  By 1929, however, the work of Hubble and others had shown that our universe is expanding. This is readily described by the expanding cosmological solutions found by Friedmann in 1922, which do not require a cosmological constant. Lemaître used these solutions to formulate the earliest version of the Big Bang models, in which our universe has evolved from an extremely hot and dense earlier state. Einstein later declared the cosmological constant the biggest blunder of his life.  He knew there was a fly in his own ointment.

Why does all this matter to us, as Black Swan mitochondriacs?

In the study of heat transfer, Schwarzschild’s equation is used to calculate radiative transfer (energy transfer via electromagnetic radiation) through a medium in local thermodynamic equilibrium that both absorbs and emits radiation.  I use this daily when I am calculating what the effect of nnEMF is on me in a particular zipcode when I am traveling.  I am on my way to Europe today.

When solar radiation is scattered it creates the phenomena that makes the sky appear blue to your brain.   For example, scattering from clear skies reflects about 32 W/m2 (about 13%) of incoming solar radiation back to space.

Visible light is also reflected and scattered by aerosol particles and water droplets (clouds). Neither of these phenomena have a significant impact on the flux of thermal solar infrared through clear skies.

You need to be bathing in that light chronically.  If you do not and use man made light to bath in I would expect one of two things to afflict you:

1.  A mitochondrial disease inflicted by the SCN on your colony of mitochondrial in some tissue linked to the leptin melanocortin pathway because of how our system is built to work in decentralized fashion.  People forget that the ipRCGs are directly wired to the SCN.

2.  A mental disorder or neurodegenerative condition because of how the leptin melanocortin pathways wire directly to the habenular nucleus without any synapses.  Today’s blog helps explain why  ALL MENTAL ILLNESSES links to the physics of light.  If you have one of these diseases or you know someone who has a history of these diseases,  you should immediately jump to the conclusions at some level in their life or their transgenerational existence, that their cells lines have been afflicted by horrible choices around light to ruin the neurotransmitters created in their brain.  They do not have a chemical deficit that requires a pharmaceutical deficit.  They suffer from a solar light deficit and/or an artificial light addiction present day or night or both.

Isreal is to Hamas as Russia is to Ukraine : War is a racket to build large government

Smedley Butler was the most decorated Marine in US history, Yet he wasn’t proud of his work. He called himself a “gangster for capitalism.”  After retiring in 1931, he toured the country, giving an explosive speech:

War Is A Racket!

What defines a racket?    An enterprise that is “conducted for the benefit of the very few, at the expense of the very many.”   War perfectly fits this definition:  Millions are maimed and killed so a few thousand can make an untold fortune

Wars are waged not for democracy or peace but for the *business interests* who profit wildly during wartime. The young men who kill and die aren’t told why they’re being marched off. Instead, they’re shamed into it.

Who profits from war, exactly?   Butler lists them:  “Munitions makers. Bankers. Ship builders. Manufacturers. Meat packers. Speculators.”  War supercharges the profits of specific industries, as their products are now demanded and bought by the ultimate spender: the government

There’s no overlap between those who fight the war – and those who profit from it. Butler reported that “21,000 new millionaires and billionaires” were minted during WW1. He asked:   “How many of them dug a trench? How many of them went hungry in a rat-infested dug-out?”

Soldiers in WW1 often got no money on “payday.”  Soldiers had to pay for their “accident insurance.”   They had to fund their own “ammunition, clothing, and food” through compulsory “liberty bonds.”   When the payday came, most soldiers got nothing in hand.

But corporations made untold fortunes in WW1. International Nickel Company’s profits jumped by “more than 1,700%.”  The US government spent billions of dollars on “airplane engines that never left the ground!”

The shoe manufacturers were suddenly in a “business with abnormal profits.”   They sold the US government 35 million pairs of shoes in WW1. General Butler writes his regiment had “only one pair” per soldier. At the end of the war, 25 million pairs were left unused.

The US army was convinced by some businessmen that “colonels shouldn’t ride in automobiles, nor should they even ride on horseback.”   6,000+ buckboards – four-wheeled carriages driven by a large animal – were sold to the government   “For the use of colonels!”   Never used

War takes ordinary men and makes them killers. Butler saw how men were taken out of “fields and offices and classrooms”  And trained to become very good at mass murder. When the war ended, they were “discharged” and told to become normal again – a reversal impossible for many.

The psychological damage of war  War gives young men “tremendous excitement.”  When the survivors return, they’re suddenly cut off from it.  These extreme swings drive some of them insane. Butler saw many veterans of WW1 in government hospitals – they were “mentally destroyed.”

How to end the racket of war?  I think the answer is to adopt Bitcoin.  Bitcoin makes war unaffordable for governments.

Those asked to fight, kill, and die should vote for the war. Butler:  “Only those who would be called upon to risk their lives for their country should have the privilege of voting to determine whether the nation should go to war.”

Concerning war, never mistake activity for achievement.

CITES

https://memod.com/jashdholani/the-rule-bending-ex-marine-hired-to-turn-the-us-in-4085

QUANTUM ENGINEERING #56: WHERE DID ABSTRACT ART COME FROM? NEANDERTHALS OR PICASSO?

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My new place in El Salvador will highlight the effect of art and light on health.  This blog will help you understand what is driving this decision process in my choices.

The “regressive evolution” of mammals today on Earth is spawning interesting new ideas for decentralized science for us that are unique.

I believe the first Hominid TBI that told the melanin story of mammals is when ancient Neanderthals lost sunlight and became modern humans.

Only wise modern humans who can see the loss of human superpower around the melanin sheets in their heads happening at breakneck speed will survive this “backward evolution”.  Wisdom for today’s mammals is born inside their melanin sheets inside their skulls.  Wisdom makes you the most adaptable creature in a rapidly changing environment.  What is changing fastest today?  The light we live under is the answer.

Let us take a walk back in history to understand what decentralized science is signaling.

Light is the creative “Source” in the universe.  To some “backward evolution” may imply a loss of complexity, misleading you to believe, that evolution has a goal of creating more complex forms. It doesn’t mean this.   However, evolution merely favors features that make a poster “more fit” for a particular current environment and this is based on the redox status of the non-visual photoreceptive system.

Consider cave-dwelling fish in Mexico below.

The cave-dwelling form of the Mexican tetra cannot see, and uses its eye sockets as repositories for fat. Credit: Barry Mansell/Nature Picture Library

Look at the fish.  Implications of the picture?  What you do isn’t what you think. Let me explain the creative process buried at the core of life.  The evolutionary process doesn’t retrace its steps in “regressive evolution”.  It just appears to those who do not carefully observe the process.  You have to go deeper than the facade of just seeing a fish with no eyes.  Cave-dwelling creatures have frequently undergone “regressive evolution”,  due to their unique light environment.  Remember fish are not mammals, but mammals have fish/amphibian OPN5 in their brains.  This creates a lesson for mammals to learn.

These fish have lost their eyes because they are not needed in dark environments. But eye loss in cavefish, for example, doesn’t mean an exact return to a primordial ancestor without these organs. The eye remnants remain.  They are atrophic and lie in wait until the light, the “Source code” returns.  Instead, processes that previously produced the eye stop partway through the process, leaving a vestigial eye overgrown with skin.  The decision to lose their eyes was a thermodynamic one.  With food so scarce in caves, the animals have to save their energy—and being sightless gives them a major energy boost​ so they can adapt to a low food environment.  This teaches us there is a huge link between light and food.  The link is thermodynamically driven.

I believe the same process occurred in the primate clade of mammals in Africa 2-4 million years ago to explain our species today.

To a surface thinker of today with low dopamine fueling their frontal lobe circuits, due to degraded melanin sheets in their skulls, things can look like they’re going into reverse when they aren’t. The eye didn’t go in reverse. It just stopped going forward.  Might human creative be the result of the same process in the chimp family?

Might it even be more complex today compared to our own genesis?

I believe this is exactly what is happening to human mammals today.  They are no longer moving forward, and their epigenetic toolbox which relies on UV light to drive mitosis, is also regressing.  What does that imply?  The cavefish doesn’t face this now because it is not a mammal and it is protected fully from man’s use of artificial light.

​What is happening to mammals that aren’t in Nature and are subject to man-made light?  Now gorillas are getting obese in zoos?  Yep.

Was Michelangelo’s David truly perfection 520 years ago in stone?  I do not think it was because his eyes and brain case where smaller than his ancestors.

​As humans have degraded the melanin sheets inside their skulls with the use of clothing and indoor dwelling with fire use they have become more creative. Look at the relationship of fire to melatonin. As fore became more popular among Neanderthals in caves their melatonin levels would have dropped.  This would have driven their blood sugars and insulin levels higher and this would have made their larger brains a real thermodynamic drag on their biology.

Who was affected by this most?  Mammals are and neanderthals were mammals.  We still see this in nocturnal mammals today.  See the link above.  Neanderthals likely went extinct over this change in light use in caves.  Could the use of fire inside of a cave to survive have given birth to homosapien creativity as we lost 125 grams of brain tissues?

I believe creativity, like autism, is a regressive evolutionary creation. Creativity manifests as a regressive change of melanin degradation to dopamine in the frontal lobes.  Autism is regressive creation in the diencephalon derivatives giving us a spectrum of change.  With respect to creativity, this regressive change has had a positive connotation which can best be seen in the Louve in Paris.  Melanin degradations created various levels of dopamine in our frontal lobes that lead to new creations on Earth.  There is a deep evolutionary lesson here.

​If this lesson offends the artist in you, good.  What did I say above?  Cave-dwelling creatures have frequently undergone “regressive evolution”,  due to their unique light environment. Mammals react just as the fish do because the OPN 5 in their brains.

Tell me, when did “human paintings” show up on Earth?  They showed up when humans went inside caves and brought fire with them to light the dwelling and they made pictures of their world on a stone wall.  They left UV-IR-A light and used alien light (fire) to light their world.  Fire is capable of destroying melatonin and melanopsin to degrade melanin.  Few see the implications as I do, but ultimately it makes sense why diseases like autism and Alzheimer’s afflict modern homo sapiens whose brains are shrinking further.

Cave art, generally, the numerous paintings and engravings found in caves and shelters dating back to the Ice Age (Upper Paleolithic), roughly between 40,000 and 14,000 years ago. The first painted cave acknowledged as being Paleolithic, meaning from the Stone Age, was Altamira in Spain.

People forget our history with light and how it is linked to our brains.  I will remind you of what you conveniently forget.  The story is right in front of your eyes.  Every day I see shrinking brains on MRI and CT scans of modern humans who have created a life around manufactured light.  It reminds me of the cavefish all the time.

Around 40 000 years ago Neanderthals went extinct.  Have you ever asked yourself why a hominid with 125 grams more brain tissue than you went extinct at Northern latitudes?  Might that answer be a lack of sunlight to fuel that brain with big eyes?  Might that brain have caused them problems when the sun’s power vanished and they began to use fire too?

I told you that the eye is the on-and-off switch of the brain.  Did you know that their Neanderthal eye socket was much larger than ours?  Is this a clue to the light story here?  Are we the result of the cognitive devolution of the Neanderthals?

For more than 350,000 years, Neanderthals inhabited Europe and Asia until, in a sudden change by evolutionary standards, they disappeared around 40,000 years ago when they faced 1000  year cooling period associated with a lack of sunlight. This was at around the same time the anatomically modern human Homo sapiens emerged from equatorial Africa where the sun was stronger. Neanderthals never got to Africa.  The story of light and lack thereof is all around our history if you look for it.

When DNA gets passed down through the generations, it gets shuffled into new arrangements that can be used to build a sort of timeline.  And this timeline suggests that the DNA entered the most northern Neanderthal gene pool roughly 100,000 years ago.

The scientists were initially skeptical of the patterns they saw in the DNA data because it said centralized science was wrong about the “Out of Africa” time line of modern homosapiens.

The most recent Neanderthal data findings challenges the current narrative that human migration out of Africa took place around 50,000 years.  In fact it raises the possibility that an earlier movement of human explorers did occur to cause the mixing of the species.

Centralized science believes Neanderthals could withstand the cold, but much new  evidence does not support this.  Few of their skeletons are found above the 51st latitude.   In fact, they got their name as a homid because the Valley of Neander is the highest latitude where most of their bones have been found in Germany.

​Neanderthals had heavier fur coats than modern humans they were covered with animal skins as the climate got colder.  This would have changed how melanin operated in their skins and brain. Neanderthals are now also thought to have processed animal hides and crafted clothing that could have covered up to 80 percent of their bodies. Do you think this had no effect on their disappearance given what I said to Rick and Huberman?  Like humans, they are thought to have covered their feet too.  Might this have affected their ability to ground as the sun got weaker?  Now we also believe other sensitive body parts, like their gonads were covered too.  Do you think this had any effect on their fecundity?  Funny how modern humans in artificial light are also now struggling with the same issues do not you think?

Another recent breakthrough was the discovery that Neanderthals may have been capable of “symbolic thought”. In my opinion, this shows something else that has already occurred in modern humans.  A regressive evolution began to cause them to lose 125 grams of brain mass when the light diminished on Earth and at the 51st latitude. In 2018, researchers announced they’d discovered evidence of cave paintings from 65,000 years ago—the oldest artworks of their kind. This art was described as abstract nature.  I find it funny that modern abstract human art began in Paris with Pablo Picasso after he locked himself inside after a friend committed suicide.  Both changes in art abstraction came with losses of sunlight.  Few see what I see.

This Neanderthal finds continue to fuel debates among scientists about how complex their mental capacities truly were, but I’d bet they were every bit as wise as us when the sun was shining.  Their candle dimmed when the sun dimmed because they had more eye mass and brain tissue to illuminate.   I think creativity is a regressive trait due to a loss of melanin because dopamine is made from it during hypoxic states.  A lack of UV light causes a pseudohypoxia.

Thoughts to ponder this AM as I look at some art to buy for the Ark down in Salvador……………..

Marie Antoinette was a story about melanin loss wasn’t it?

SUMMARY

Everything has beauty, but not everyone sees it for what it really is.  Observing nature in her raw form taught me that her many realities hidden behind a wall of perception.  That vision is created not just what we see, but what we hold to be true.  I learned from Nature that it is ideal to hide your best secrets; this is why I like seeing people when they can’t see the real me.  You might begin to watch the world around you with glittering eyes because the greatest secrets are always hidden in the most unlikely places.  I watch nature in her raw form at every sunrise.  I never miss these lessons.

CITES

https://en.wikipedia.org/wiki/Neanderthal_1

QUANTUM ENGINEERING #55: CELLULAR TIME STAMPING

Post translational time stamping is present from cyanobacteria to mammals.  All organisms have evolved timing mechanisms to adapt to environmental changes in order to optimize survival and improve fitness for an environment. To anticipate these regular daily electromagnetic cycles of light and dark, many organisms manifest near 24-h cell-autonomous oscillations that are sustained by transcription–translation-based or post-transcriptional negative feedback loops that control a wide range of biological processes. With an eye to identifying emerging common themes among cyanobacterial, fungal and animal clocks, some major recent developments in the understanding of the mechanisms that regulate these oscillators and their output need to be discussed. These include roles for antisense transcription, intrinsically disordered proteins, codon bias in clock genes, and a more focused discussion of post-transcriptional and translational regulation as a part of both the oscillator and output.

Circadian rhythms in every organism are cell autonomous, appear to have arisen only a few times in evolution, and can be driven by one of a few lineage-specific but otherwise highly conserved central oscillators. While oscillators driving bacterial and plant clocks are distinct from each other and from other known clocks, fungal and animal cells share circadian oscillators of conserved regulatory architecture: transcription-translation feedback loops (TTFLs) comprised of two parts.

Specifically, 1) a positive arm with a heterodimeric complex at its core that behaves as the activator of the system, promoting the transcription of 2) one or more components of the negative arm, which when translated inhibit the activity of the positive arm.

WHAT IS THE TTFL?

Transcription-translation feedback loop (TTFL) is THE cellular model for explaining circadian rhythms in behavior and physiology. It is widely conserved across species, and the TTFL is largely auto-regulatory with the assistance of the sun & moon and dark periods on Earth, in which transcription of clock genes is regulated by their own protein products. This implies that light and dark control genetic expression and not the other way around. The TTFL is a negative feedback loop, in which clock genes are regulated by their protein products. Generally, the TTFL involves 2 main arms: positive regulatory elements that promote transcription and protein products that suppress transcription. When a positive regulatory element binds to a clock gene promoter, transcription of DNA proceeds, resulting in the creation of an mRNA transcript, and then translation proceeds, resulting in a semiconductive protein product. There are characteristic delays between mRNA transcript accumulation, protein accumulation, and gene suppression due to translation dynamics, post-translational protein modification, protein dimerization, and intracellular travel to the nucleus. Across species, proteins involved in the TTFL contain common structural motifs such PAS domains, involved in protein-protein interactions, and bHLH domains, involved in DNA binding.

The two overarching areas characteristic of circadian systems in general: 1) the negative arm and its regulation of the core clock; 2) the control of output by the positive arm and its environment.

In ALL mammals the heterodimeric BMAL1-CLOCK complex positively regulates expression of negative arm component genes, the Periods and Cryptochromes(encoding PER1, PER2, PER3, CRY1 and CRY2), that combine with CK1 and several other proteins to make the repressive complex that depresses BMAL1-CLOCK activity and alters periodicity of the mammalian clock which alters its accuracy.  Remember all circadian clocks are flow meters for entropy in a cell.

Solar light input into mammal TTFLs begins with dedicated non visual photoreceptors that elicit signaling that acts to induce (in fungi and mammals) or reduce (insects) the amounts of negative arm proteins mentioned above. In broad outline, Output occurs when the positive Arm heterodimer binds to DNA and activates expression of genes whose products do not impact the TTFL.  The key take away is the clock gene actions are PROXIMAL to DNA translation and gene activation.  This tells you that light inputs controls gene expression in mammals and it is not the other way around.  Altering your genome will not improve your illness or disease if the light and dark environment is repair first.

HOW DOES TIME STAMPING WORK BY LIGHT AND DARK WORK?

Once enough modified protein products accumulate in the cytoplasm of a cell, they are transported into the nucleus where they inhibit the positive element from the promoter to stop transcription of clock genes. The clock gene is thus transcribed at low levels until its protein products are degraded, allowing for positive regulatory elements to bind to the promoter and restart DNA transcription. The negative feedback loop of the TTFL has multiple properties important for the cellular circadian clock. First, it results in daily rhythms in both gene transcription and protein abundance and size, caused by the delay between translation and negative regulation of the gene. The cycle’s period, or time required to complete one cycle, remains consistent in each individual and, barring mutation, is typically near 24 hours. This enables stable entrainment to the 24 hour light-dark cycle that Earth experiences from the sun & moon.

Additionally, the protein products of clock genes control downstream genes that are not part of the feedback loop, allowing clock genes to create daily rhythms in other processes, such as metabolism, within the organism. Light and dark cycles are the decentralized controllers of the TTFL.

THE TTFL USES MELANIN TO ELECTROCHEMICALLY TIME STAMP YOUR CELLS. This occurs in the retinohypothalamic pathways anterior to the SCN and it modifies what the SCN signals to all the other molecular clock genes it links to in tissues.

WHY IS MORNING LIGHT SO CRITICAL TO GET RIGHT?

CSP-1 (conidial separation 1) is a morning induced transcriptional repressor with a phosphorylation gated half-life is a key cog in driving EVENING gene expression in mammals.  If you do not get AM sun your evening genomic expression will be AWRY.  People have forgotten that leptin is released by fat cells and can only enter the hypothalamus under darkness after 4 hours. This should happen at night time. It cannot happen when CSP-1 is not created by AM light.  These are the new recent insights into how circadian clocks in your eye and skin achieve phase-specific gene expression.  This is how and why leptin resistance exists.

The negative element of the core circadian feedback loop is the frq or frequency gene.  The frequency (frq) gene controls the morning-specific rhythmic transcription of a sense RNA encoding FRQ segment.  As a result of this action, a long noncoding antisense RNA, qrf, is rhythmically transcribed in an evening-specific manner.  It has been reported in the literature that the qrf rhythm relies on transcriptional interference with frq transcription and that complete suppression of qrf transcription impairs the circadian clock.  The biological function of qrf transcription and its impact on the circadian clock are not understood in centralized science because centralized science has no light controls at night in labs.

CSP-1 expression is induced by light and glucose, and this finding suggests a rhythmic coordination of qrf transcription with metabolism.  Because it is light and glucose we know POMC, ACTH, and melanin are the key to understanding CSP-1 biology.   It also means that artificial light during the day or night is especially toxic when you know this is how the mechanism operates.

There are three type of melanins in humans and only one ACTH in humans. All three are used to time stamp the atomic lattice of cells to create an internal map of space time domains to be accurate measuring sticks for the flow of entropy inside of cells. This links melanin biology to Noether’s theorem directly.  You have blogs on all these ideas now and it is time for you to link them all to comprend what I have been teaching your for 20 years.  Light causes modern diseases.

These 3 melanins are ALL extended heterogeneous biopolymers composed of molecular subunits with ambiguous macromolecular topology to modern centralized science. In the literature, an electrochemical fingerprinting technique has been described for melanin, which suggests that natural melanin pigments which contain indole-based tetramers seem to be always arranged into porphyrin-like domains to capture light and measure it in some way useful to the system.

Spectroscopy and density functional theory calculations suggest that sodium ions undergo occupancy-dependent stepwise insertion into the core of porphyrin-like tetramers in natural melanins at discrete potentials that time stamp the internal atomic lattice that allow it to act like a clock to measure the flow of entropy in the cellular system accurately just using light and dark as the feedback loops. It is fully decentralized because light and dark control this process. One is not more important than the other. A loss of melanin implies a loss of accurate time keeping inside the cell or tissue.

Lastly, in humans, the TTFL is a limit cycle, meaning that it is a closed loop that will return to its fixed trajectory even if it is disturbed by its environment, maintaining the oscillatory path on its fixed 24-hour period. It appears this is only true if the melanin structures it uses on surfaces and endogenously remain intact and are chronically replaced and renovated. If the endogenous electrochemical time stamping mechanism is damaged, the TTFL loses its periodicity and chronic modern disease results without any alteration to the DNA or RNA of a cell. These are diseases do not mimic genetic diseases like Tay Sach’s. These diseases are far more common than mutational diseases of DNA which are relatively rare. It means our circadian mechanism is open to the environment, and as such is not subject to calories measurement for metabolism because calories only is useful in closed thermodynamic loops.

CITES

1. Aronson BD, Johnson KA, Loros JJ, Dunlap JC. (1994) Negative feedback defining a circadian clock: autoregulation of the clock gene frequency. Science 263:1578-1584.

2. Belden WJ, Larrondo LF, Froehlich AC, Shi M, Chen CH, Loros JJ, Dunlap JC. (2007) The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output. Genes Dev 21:1494-1505.

3. Bell-Pedersen D, Shinohara ML, Loros JJ, Dunlap JC. (1996) Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific. Proc Natl Acad Sci U S A 93:13096-13101.

4. Cheng P, Yang Y, Heintzen C, Liu Y. (2001) Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J 20:101-108.

5. Dunlap JC. (1999) Molecular bases for circadian clocks. Cell 96:271-290.

6. Froehlich AC, Liu Y, Loros JJ, Dunlap JC. (2002) White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter. Science 297:815-819.

7. Gallego M, Virshup DM. (2007) Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol 8:139-148.

8. Larrondo LF, Olivares-Yanez C, Baker CL, Loros JJ, Dunlap JC. (2015) Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination. Science347:1257277.

9. Baker CL, Loros JJ, Dunlap JC. FEMS Microbiol Rev 2011

10.  Transcriptional interference by antisense RNA is required for circadian clock function.

Xue Z, Ye Q, Anson SR, Yang J, Xiao G, Kowbel D, Glass NL, Crosthwaite SK, Liu Y.Nature. 2014 Oct 30;514(7524):650-3. doi: 10.1038/nature13671. Epub 2014 Aug 17.

11.  Molecular Regulation of Circadian Chromatin.

Zhu Q, Belden WJ.J Mol Biol. 2020 May 29;432(12):3466-3482. doi: 10.1016/j.jmb.2020.01.009. Epub 2020 Jan 16.

12.  Koike N, et al. Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science. 2012;338(6105):349–354.

13.  Li N, et al. The frequency natural antisense transcript first promotes, then represses, frequency gene expression via facultative heterochromatin. Proc Natl Acad Sci U S A. 2015;112(14):4357–4362.

14.  Xue Z, et al. Transcriptional interference by antisense RNA is required for circadian clock function. Nature. 2014;514(7524):650–653.

QUANTUM ENGINEERING #54: MISSING INTERNAL MELANIN, ADHESIONS, KELOIDS, & ALS. WHY ARE THEY ALL LINKED?

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POMC arose over 500 million years ago by an insertion of the melanocortin sequences into a prepro-endorphin gene. Evidence for this comes from structural identities with other opioid precursors in both the NH2- and COOH-terminal regions of POMC.

The phenomena of pro-opiomelanocortin (POMC) as a hormone precursor emerged gradually over time as observations slowly filled in pieces of the puzzle. Long before the concept of hormone precursors was realized, the bronzed skin color described by Addison in his patient with adrenal insufficiency (“melasma suprarenale”) gave perhaps the first hints of a connection between the hypothalamic, pituitary, adrenal (HPA) axis and skin color. A similar link between the pituitary and pigmentation came from the studies of Allen in 1916 and Smith in 1916 who both noted that immersing tadpoles in pituitary extract made their skins darker. In humans too, large doses of porcine pituitary extract also appeared to cause pigmentation in 1954, with this active extract of the pars intermedia of the pituitary henceforth termed “melanocyte stimulating hormone” or MSH.

In 1932, Cushing extended his clinical reports of a polyglandular syndrome caused by basophilic adenomas of the pituitary by linking this finding with adrenal hyperactivity. In the 1930s, work by Ingle and Kendall in the 1930s showed that administration of large amounts of “cortin,” a purified adrenal extract, produced atrophy of the adrenal cortex in rats. Importantly, they found that administration of the “adrenotropic principle” of the anterior pituitary was effective in preventing adrenal cortical regression following treatment with cortin. The first hints of a behavioral angle to POMC biology came from studies by Ferrari in the 1950s, when “stretching-yawning syndrome,” a bizarre crisis of muscular tone, occurred following central administration of MSH. Many other studies assessing the effects of central α-MSH on motivational processes followed, but it was not until 1976 that Panskepp observed for the first time that this peptide decreased food intake using light alone.  What else might POMC do in a modern world run by artificial light now?  Today, you get to see another perspective centralized science missed.

Viewed from the comfort and assured knowledge of the modern centralized molecular world, these observations and interventions could be considered overtly simplistic. However, I believe that these classic decentralized observations should be regarded as essential building core evolutionary building blocks, not only for our understanding of POMC peptide processing, but also for the work which subsequently tied together these seemingly diverse peptides.

Is this why did I had a ubiquitnation & mitochondrial series before the Quantum Engineering series on Patreon?

Yep.

In mammals, a master clock localized in the suprachiasmatic nucleus of the hypothalamus synchronizes cellular clocks in other central nervous and peripheral tissues with each other and with external time. At the molecular level, these clocks are based on an interregulatory network of clock genes, including the 3 Period genes (Per1–3), that control circadian rhythms (CRs) by rhythmic orchestration of 5–10% of the cellular transcriptome in a post translational tissue-specific manner.  CRs time stamp genes after they are translated and cause diseases.  I relayed this last month to the government of El Salvador in a speech I gave there.

Transcription-translation feedback loop (TTFL) is a cellular model for explaining circadian rhythms in behavior and physiology. Widely conserved across species, the TTFL is auto-regulatory, in which transcription of clock genes is regulated by their own protein products. Rev-erba is one and so is NF-kappa beta.

THIS IMPLIES TIME STAMPING CAUSES CHRONIC NEOLITHIC DISEASES.

What can we use as an example to see if light stress on out largest organ causes diseases below?

I posted the video above to show you how centralized edicational materials still miss the obvious elephant in the room.  The lights used in surgery can cause the problem.  the lights on laparascopic cameras are all high intensity blue lights, and it is already well know that other parts of the electromagnetic spectrum used in medicine can cause this problem without any previous surgery.  Look at the picture below that I lifted from the video to show you how their own video on this topic misses the elephant in the room on adhesions.  I even mentioned this to Huberman during my podcast when I told him everytime I open a skull I now worry about what I am doing because of my understanding.

Have you ever heard of adhesions of the gut?

Abdominal adhesions commonly form after intra-abdominal surgery, radiation, and inflammatory processes in humans. In a subset of patients, adhesions lead to problematic symptoms such as abdominal pain, bloating, and bowel obstruction. The mechanisms of adhesiogenesis are not well understood by centralized science but are believed to involve mesothelial surface disruption with subsequent fibrinocoagulative and inflammatory signaling processes. I believe the reason centralized science has missed the boat on adhesions is because aberent light causes it. It is a biophysical disease at its core.  Melanin in your omentum is a big deal to the gut clocks below.  The melanin in the omentum links to the POMC genes in the skin of the rectus sheets on your abdomen.

WHAT ARE ADHESIONS?

Abdominal adhesions are fibrous bands that span two or more intra-abdominal organs and/or the inner abdominal wall (i.e. peritoneal membrane) which typically form after abdominal surgery. Adhesions may also form secondary to inflammatory conditions of the abdomen in the absence of prior abdominal surgery or as a sequela of abdomino-pelvic radiation. Although the majority of patients with intra-abdominal adhesions remain asymptomatic, a clinically significant subset of patients will develop “adhesive disease”, a symptomatic state ranging from mild and/or vague to highly distressing and even life-threatening symptoms.

Considering the fact that adhesions have no characteristic laboratory features and are not readily visible by currently available imaging methods, many cases of adhesive disease will go undiagnosed for prolonged periods of time, causing medical providers to find themselves in a diagnostic and therapeutic quandary. Patients, consequently, after extensive non-diagnostic testing and empiric treatments, may not only experience protracted symptoms and adverse medical outcomes, but can also suffer from significant emotional distress or demoralization, which in turn may be misdiagnosed as depression, anxiety, or a functional bowel disorder.  This topic was going to be the headliner in 2019 in Vermont.  That never happened.

WHAT IS THE LIKELY DECENTRALIZED CAUSE OF ADHESIONS?

Irradiating human skin with blue light in frequency bands that causes both type of blue light toxicity is likely the cause of abdominal adhesions. People with autoimmune conditions are at increased risk of adhesions and keloid formation on their skin. The link between all these conditions is the chronic irradiation of human skin with artificial blue light devoid of IR- A and UV frequencies with blue light. One must remember that isolated blue frequencies activates the blue light hazard in mitochondria powered by melanopsin signaling that cause pseudohypoxia in mitochondria. When will centralized medicine learn how light stress not from sunlight ruins mitochondrial biology?  Melanin is a key battery in the skin and deep inside of our systems.

This type of isolated light irradiation can set up adults for epithelial cancer, myopia, low dopamine diseases, diabetes, and skin cancer as they age and their heteroplasmy rates grow larger faster as they age into adults formats. If you destroy the battery you have no energy left for health and disease is the result.  Could it also be the cause of adhesions?  Might this mean adhesions in the gut are a warning signal that surgeons should be paying attention to in patients?

It is for me.  When i see arachnoid webs in the brain I know what it means to my patients.

Women with keloids on their cesarean scar have been found in prospective studies to have increased adhesions between the uterus and the bladder and between the uterus and the abdominal wall. This certainly supports my theory and my ideas on this topic. This is cited below.

In mammals, a master clock localized in the suprachiasmatic nucleus of the hypothalamus synchronizes cellular clocks in other central nervous and peripheral tissues with each other and with external time. At the molecular level, these clocks are based on an interregulatory network of clock genes, including the 3 Period genes (Per1–3), that control circadian rhythms (CR) by rhythmic orchestration of 5–10% of the cellular transcriptome in a post translational tissue-specific manner. This tells us that most human disease is not DNA/RNA based, it is mitochondrial based because circadian disease phenotypes mimic those of chronic diseases in centralized healthcare. Circadian biology and oscillations time stamp genes after they are translated and cause modern chronic diseases. How does it happen in humans?

Transcription-translation feedback loop (TTFL) is a cellular model for explaining circadian rhythms in behavior and physiology. It is widely conserved across ALL species, & the TTFL is auto-regulatory, in which transcription of clock genes is regulated by their own protein products. Rev-erba is one and so is NF-kappa beta.  I’ve written about both of these things in the past on my blogs.

Rev-erbα, a nuclear receptor and circadian clock component, is a mediator of microglial activation and neuroinflammation in the connection between the CNS and human gut.

I believe people who get adhesions (Crohn’s, UC, SIBO patients) all have destroyed Transcription-translation feedback loop destuction due to an altered circadian mechanism. I propose that such a mechanism can be found within the molecular control of circadian rhythms and “Clock” gene biology and a lack of melanin in some key places in the spinal cord that connect the gut to the CNS.

All melanin’s can create a toxin when they breakdown in human tissue.  For example, neuromelanin can reversibly bind and interact with amine containing neurotoxins, (e.g., MPTP(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is an organic compound. It is classified as a tetrahydropyridine.) MPTP augments their actions in the terminal, eventually leading to the instability and degeneration of melanin-containing neurons due to oxidative stress and mitochondrial dysfunction.

In particular, a lack of neuromelanin and POMC translation by a lack of UV light appears to confer susceptibility to chemical toxicity by providing a large sink of iron-bound, heme-like structures in a pi-conjugated system. This system seemingly allows for stabilizing interactions including pi-stacking, sodium inclusion,  as well as ligand binding to iron in cells. Given the progressive accumulation of neuromelanin components with aging. it seems melanin degradation corresponds with an apparent decrease in dopamine synthetic pathways in man.  This raises an immediate question of whether melanin can also create or is capable of binding dopamine, the primary functional monoamine utilized in gut enterocytes and its corresponding gut neurons, should be raised by centralized research.  To date, it has not been.

A number of physiological processes demonstrating circadian variation have been shown to involve ‘Clock genes’ in the suprachiasmatic nucleus (SCN), which then entrains a similar set of Clock genes in peripheral tissues such as the heart, brain, spleen, lung, liver, skeletal muscle and kidney. The intrinsic time-keeping system influences activity, such as sleep, temperature regulation, rates of metabolism, immune responses, blood pressure and hormone secretion. The function and availability of mediators involved in the inflammatory response, fibrinolytic and anti-coagulation pathways are all under the tight control of the molecular Clock system. These include IL-6, PAI-1, fibrinogen, fibroblasts and TNF-α. I am making the educated guess that disruptions in the ‘Clock system’ are central to the causal pathway of adhesion formation here.  I am also implying this symptom is a gateway disease to many other diseases linked to altered cellular time stamping in humans.

The transcriptomic analysis of hippocampus from Rev-erbα-/- mammals has revealed a predominant inflammatory phenotype results in mammals and it suggests it comes from a dysregulated NF-κB signaling due to circadian dysfunction at its core.  When one considers that melanin derivatives are always found in pathologic specimens it is not hard to come up with this linkage.

DEEP DECENTRALIZED SCIENCE THEY ARE MISSING

The brain gut connection requires pristine circadian rhythm control to stay healthy. Loss of Rev-erbα in primary astrocytes of the spinal cord of mammals had no effect on basal activation of the neurons that innervate the gut but do potentiate the inflammatory response to lipopolysaccharide (LPS). In vivo, Rev-erbα-/- in a mammalian model has exhibited enhanced hippocampal neuroinflammatory responses to peripheral LPS injection, while pharmacologic activation of Rev-erbs with the small molecule agonist SR9009 suppressed LPS-induced hippocampal neuroinflammation. This explains to us how a loss of circadian control allows the LPS of the microbiome to lead to a disease phenotype just with a loss of circadian control post translationally of DNA.  This means DNA alteration is not the cause of a majority of modern human disease.  This is 180 degrees from the current centralized perspective.

Rev-erbα deletion due to a loss of clock gene control clearly influences gut enterocyte function and neuronal health in a coordinated fashion. When this link breaks it makes the formation of adhesions post surgically much more likely. Lab experiments done have shown when gut neurons are conditionally cultured on media from Rev-erbα-deficient primary gut-glial cultures, it exacerbates oxidative damage in cultured neurons that innervate the gut. Rev-erbα-/- mammals have not only shown gut dysfunction in these models but they also exhibited significantly altered cortical resting-state functional connectivity. This finding tells me that many central neurological diseases maybe masquarding in centralized medicine clinics as circadian diseases of the Transcription-translation feedback loop(TTFL).

One neurologic disease in particular intrigues me with its skin & gut connection is ALS. ALS patients tend not to show up in low latitudes and they tend to be quite pale because they lack UV exposure POMC requires for translation of melanin. In human ALS, abnormalities have been found in mitochondrial structure, mitochondrial respiratory chain enzymes, and mitochondrial cell death proteins indicative of some non-classical form of programmed cell death.  In ALS patients this happens in the spinal cord, skin, and their gut in pulsatile fashion over timescales.  This is a hint to me that it might be a disease of time stamping of the TTFL masquarading as a neurological disease.

The creation of MPTP, which is lipid-soluble, readily penetrates the blood—brain barrier and enters the brain cells. Because it is amphiphilic, it is captured into acidic organelles, mostly lysosomes, of astrocytes. MPTP itself does not appear to be toxic, but its oxidized product, 1-methyl-4-phenylpyridinium (MPP+), is toxic. This has been linked in Parkinson’s Disease but I think it might link to ALS because the toxic MPP+ could affect defective mitochondria in neurons in the anterior motor horn from circadian rhythm damage in the gut. These malfunctioning mitochondria might contribute to neuronal death in ALS through the biophysical entity called the mitochondrial permeability pore (mPTP) activation.

The major protein components of the mPTP are enriched in mammalian motor neurons which also have abundant POMC genes. Early in the course of disease in ALS humans seem to present with mutant superoxide dismutase-1 enzymes in their mitochondria. The mitochondria in motor neurons undergo “trafficking abnormalities” which results in dramatic remodeling of mitochondria in ALS patients that results in the formation of mega-mitochondria (larger size) and coinciding with increased protein carbonyl formation and nitration of mPTP components. Anything that enlarges is a thermodynamic sign to me.   In fact, lab experiments in nocturnal mammals have shown that genetic deletion of a major mPTP component called cyclophilin D which has robust effects in ALS by delaying disease onset & phenotype and extending survival of the anterior motor neurons.

When this process is disrupted the MPP+ action it appears to destroy the mPTP in a cascading manner in the spinal cord mitochondria and spreads like an infection would in the anterior motor neurons. I think the circadian disruption in the anterior motor neurons causes a paralysis like effect that we normally see in REM sleep. In ALS, the circadian disruption shows up when we are awake and it has gone unrecognized as a completely disrupted rhthym disorder because of how we perceive the disease and we have not looked at the data carefully enough. I happen to have one person with this disease who is doing something no one else has done with this diagnosis. He is improving his solar redox and improving mtDNA function by living in the tropics adjacent to a flat beach. So far he is doing a lot better than other ALS patients who aren’t paying attention to their light stamping problem.  In fact, I believe some of these patients diseases are made worse when they travel outside of time zones.  That seems to make the diseases more aggressive.

I think this model in mammals explains why anterior motor neurons can be destroyed in isolated fashion in the spinal cord when the circadian rhythms are disrupted in the nerves that innervate the gut but link back to their embryologic origins. The inflammatory cascade could start out in the splanchnic nerves below but as the spinal cord anterior motor neurons loses REV-erb alpha it could create an inflammatory cascade of LPS induced damage to “infect” other adjacent motor neurons by destroying their clock gene TTFL’s. This is how ALS might be progressing in these patients.

The Rev-erbα, mPTP in mitochondria, and TTFL should be thought of as as a key biophysical link between the circadian clock control and neuroinflammation in the CNS.  People forget that the spinal cord is part of the CNS and so is their skin. Nerves link the gut to both.

Look more carefully at the picture above then you did in QE #47.  Note the skin is on the left of the picture and it is our largest organ and it has a somatotopic organization to the ENTIRE spinal cord and to our internal organs by way of nerves.

The Quantum Enginnering #47 blog has the key metric of why the eye, skin, PVN, and DLF of the brain stem sleep and pain areas give the input into celiac plexus to cause gut problems via the microbiome. The implications of this connection are massive in many other diseases besides bipolar disorder. I told you that there and I am doubling down on it here.

WHAT DID I SAY IN QE #47 AGAIN ABOUT THIS PROCESS?

I said, “The dorsal longitudinal fasciculus (fasciculus of Schutz) is a periaqueductal (area around ventricular system Aq above) ascending and descending fiber system arising from the hypothalamus and terminating to the autonomic nuclei of the pons and the medulla, conveying autonomic fibers from the brain to the gut in humans.  It also conveys pain messages and is important in the sleep pathways of humans.  These are usually altered in bipolar patients as well because of a lack of melanin in these areas.

The dorsal longitudinal fasciculus is found within the dorsal brainstem tegmentum. It passes through the periaqueductal gray matter and contains both ascending and descending fibers. The ascending fibers pass from the reticular formation (sleep region/insomnia) passing to the hypothalamus thus transmitting information related to the viscera in the thorax and abdomen.  THIS IS HOW THEY PASS THE ANTERIOR MOTOR HORN CELLS AND THE GUT VISCERA!

People who travel a lot across time zones or people who use a lot of blue light or nnEMF at night or day in their cities are going to have massive sleep disturbances because they lack charge density in this spot.  They mimic people with mental disorders like bipolar patients because they have broken the same rules of Nature.  I view insomnia as a mental disorder in my decentralized medicine framework.

This topologic neuronal surface is a critical barrier to the brain health of humans.  This is the pathway where metabolic syndrome, poor sleep, and fatty liver all come from fundamentally.  This pathway could be in many blogs but I left it out this detail.  Why?  You already thought this stuff was too hard.  Why add another level of complexity with neuroanatomy?

Many of these same findings are found in diabetics, bipolar disorder, and those with sleep disorders like insomnia.  Patients with bipolar disorder tend to have all these symptoms at times that vary based on how defective their FM antennae are in their eyes & brains.”

DOES ANYONE SEE THOSE LINKS NOW IN THIS BLOG IN THE SERIES?

Now, go back and look at the lipofuscin blog in this series.  That chemical comes from melanin degradation and is always associated with aging and light stress.  Dopamine is made in the eye several ways by sunlight and it can be made in the gut by your microbiome due to the link to melanin. People forget that bacteria release 5000 times more light than eukaryotic cells and this light is capable of making dopamine from the aromatic amino acids in the gut. This is why serotonin and phenylalanine and tyrosine are stored in the enterochromaffin system in our gut.

The more and more you look into its biology, I feel more confident in saying that light is the most powerful drug for living systems. The light release is more important than the fuel in the diet for our health outcomes because food has light information built into photosynthesis. This stimulus leads to light release to start the optical signal cascade in the gut using aromatic amino acids as the mover in the GI tract. When you are blue light/nnEMF toxic you cannot repair the gut or sleep issues at all. This is why many people get gut adhesions without having had any surgery.  The same thing will be true for pain thresholds and opiate use. I can tell you this. Your gastrointestinal system will never function optimally in a circadian mismatch (melanopsin/encephalopsin dysfunction) and that will bypass however good a diet is.

The study linked below in cite 6 is a longitudinal study on TBI following college football athletes across a sports season.
•Nanopore 16S rRNA sequencing of gut microbiome reveals changes after head injury.
•Serum biomarker GFAP increased during the competitive period of the season.
•S100β and SAA blood levels were positively correlated with Eubacterium rectale.
•Gut microbiota is suggested as a future biomarker for diagnosis following head & neck injury.

The blue light hazard/nnEMF links the gut to the brain, heart, and vascular damage leading to neurodegeneration that causes protein folding issues in blue light-damaged tissues as cites 4 and 5 show. Few are making these links in diseases like adhesions and ALS.

But I am.

CITES
Van Goor H. Consequences and complications of peritoneal adhesions. Colorectal Dis. 2007 Oct;2(9 Suppl):25–34.
Menzies D., Ellis H. Intestinal obstruction from adhesions; how big is the problem? Ann. R. Coll. Surg. Engl. 1990;72:60–63.

Sjogren syndrome and abdominal adhesions.Could they be related?

Background: Sjögren syndrome is a chronic systemic inflammatory disorder (classified as an autoimmune disorder) characterized by lymphocytic…

egojournal.eu

https://www.bmj.com/content/362/bmj.k3549

Blue light-induced retinal lesions, intraretinal vascular leakage and edema formation in the all-cone mouse retina – Cell Death & Disease

Little is known about the mechanisms underlying macular degenerations, mainly for the scarcity of adequate experimental models to investigate cone cell death. Recently, we generated R91W;Nrl−/− double-mutant mice, which display a well-ordered all-cone retina with normal retinal vasculature and a…

Alterations to the gut microbiome after sport-related concussion in a collegiate football players cohort: A pilot study

Concussions, both single and repetitive, cause brain and body alterations in athletes during contact sports. The role of the brain-gut connection and …

sciencedirect.com

Prospective study of intraabdominal adhesions among women of different races with or without keloids – PubMed

Allen BM. Extirpation experiments in Rana pipiens larvae. Science 44: 755–757, 1916. doi: 10.1126/science.44.1143.755.

Smith PE. Experimental Ablation of the Hypophysis in the Frog Embryo. Science 44: 280–282, 1916. doi: 10.1126/science.44.1130.280.

Lerner AB, Shizume K, Bunding I. The mechanism of endocrine control of melanin pigmentation. J Clin Endocrinol Metab 14: 1463–1490, 1954. doi: 10.1210/jcem-14-12-1463

.Ingle DJ, Kendall EC. Atrophy of the Adrenal Cortex of the Rat Produced by the Administration of Large Amounts of Cortin. Science 86: 245, 1937. doi: 10.1126/science.86.2228.245.

Panskepp J, Reilly P, Bishop P, Meeker RB, Vilberg TR, Kastin AJ. Effects of alpha-MSH on motivation, vigilance and brain respiration. Pharmacol Biochem Behav 5, Suppl 1: 59–64, 1976. doi: 10.1016/0091-3057(76)90329-4.