Author: info@kruseatdestin.com

The biophysics of the Southern Hemisphere is an interesting topic for those with coupled and uncoupled haplotypes. The story of trees has a lesson for you.

Today I am on day 7 on the journey to Antarctica and 6 days after the Summer solstice here. I’m currently quite close to 41-S latitude in the summer, close to the red pin below. The weather here is much colder than one would expect in the summer than we would see on June 27th at the 41N latitude.

In the United States, the 41 N parallel defines the southernmost border of Wyoming, which borders Utah and Colorado, and is part of the border between Nebraska and Colorado. The difference is that the 41 S latitude surrounds the Southern Ocean. The southern Hemisphere is covered by 80.9% ocean. The Northern Hemisphere is covered by 60.7% ocean. The physics of water and light explains the difference. Because the Southern latitudes have more seawater, water heats up and cools down more slowly than land does. This affects the oceanic heat transfer via the physics of the thermohaline currents.

Thermohaline currents work on water density, which is affected by its deuterium content. These currents refer to the movement of ocean water driven by differences in temperature and salinity, which in turn affect seawater density.

This circulation is responsible for distributing heat and nutrients throughout the world’s oceans and is essential for maintaining a specific climate for a region.

Winds and ocean currents play a significant role in the thermohaline circulation by driving the movement of surface water and climate in a region. This impacts life on land.

When ocean water in the polar regions gets very cold, sea ice forms, and the surrounding seawater becomes saltier, denser, and sinks to the bottom of the ocean as the ice stays on top. The ice is deuterium depleted compared to the seawater.

This physical effect translates directly to photosynthesis in South America and Antarctica. There are collateral effects in Australia. Forests in the Southern Hemisphere have distinct differences that take advantage of this. Chile, Argentina, and Australia have unique beech species called Nothofagus. This extends to NZ as well. NZ has a closely related genus called Lophoozonia and Fuscospora. As a result, Australia is loaded with eucalyptus. In the 19th century, eucalyptus was brought to South America, and it does well on this continent because of the hydrology cycle of lowered deuterium water.

How species respond to the combined effects of lowered temperature and low soil moisture depends on species tolerance, the range of environmental conditions, and extreme temperature and precipitation changes. Low soil moisture in the early summers in the Southern Hemisphere can impact leaf-level photosynthesis through stomatal regulation and nonstomatal processes (Flexas & Medrano, 2002). This is why, at high southern latitudes, the forests are not as dense as they are in North America.

Reduced moisture decreases stomatal conductance, and thus leaf photosynthetic CO2 assimilation due to a reduction of CO2diffusion and thus lower intracellular CO2 concentration in the leaf (Ci) (Gallé & Feller, 2007; Zhou et al., 2014), leading to a possible photo-damage to PSII (Powles, 1984; Epron & Dreyer, 1993). Independently of stomatal closure, biochemical processes will be affected during prolonged soil moisture reduction, thereby limiting leaf-level photosynthesis properties via the downregulation of Rubisco activity and content (Parry, 2002). Hence, impacts of low soil moisture could include a reduction of Asat, Vcmax, Jmax, and Fv/Fm (Zhou et al., 2014; Santos et al., 2018). CO2 from volcanoes at the bottom of the Earth feeds the plants CO2 chronically.

Exposure to chronically lowered air temperature with sufficient soil moisture supply should increase leaf-level photosynthetic properties in the long term because of enhanced photochemical reactions, as long as temperatures do not exceed the photosynthesis optimal temperature. The elevations of the Andes show these effects on plant life throughout Chile and Argentina. The Earth creates mountains and volcanoes to seed the Earth with fuel to grow plants and trees.

The eucalyptus replantation was a success because man used Nature’s processes in South America to produce pulp and biofuels.

This is the decentralized science of the biophysics of water and light. Water and light control this process, which affects you via your heteroplasmy rate. This is how light and water sculpt life in the Southern Hemisphere. The process is not the same in both hemispheres. People who are tightly coupled will do terribly at high southern latitudes.

I have done several Q & As for my members about the new data in the jab from many researchers. I call the sun the vaccine for cancer in animals on Earth. I say this because just about every paper I read that is new shows this effect. It is also why EVERY paper in the PEER literature I have reviewed that looks at Vitamin D3 levels links it to cancer risk and low melatonin levels.

I’ve made the case that to avoid cancer caused from the jabs one must constantly live in an environment where the sun power is always controlling this mechanism so that one gets no breakthrough cancer. And if one does get a break through turbo cancer one must have serious redox power in their T- regulators cells to take the cancer out once it forms.

If you watch the Vermont 2017 video on Utube, then you will see why AM light keeps you far from the cancer state.   AM light has more IR-A and NIR light. These two light bands also offer unique protection from jab cancers. This new paper from June of 2024 shows this.

WHY IS LIGHT IRREPLACEABLE IN TREATING JAB INDUCED TURBO CANCERS?

Light controls the size and shape of cells and mitochondria. Size and shape of mitochondrial controls the thermodynamics possible in an organs mitocondria to either facilitate cancer generation or inhibit it. The volume change in a cell of a mitochondrion is quantized to light frequency and charge of the cells in question.  Light is directly coupled to the redox power in your mitochondria. Nothing else has this lever of control. This biggest key to volume control in mitochondria is the deuterium fractionation in the cell over all.  Where this fractionation occurs is also huge in determining what kind of disease you get. When it develops inside the mitochondria cancer is the most likely diagnosis.

So when a cell loses energy, it gets larger, and it can become oncogenic because the size change alters how the tensegrity of the cell operates to pull chromosomes apart.  Our body uses size and shape change as a signal to our immune systems NK cells as a defense mechanism in this case to prevent oncogenesis. This process is altered by the jabs.  The jab itself is a mitochondrial toxin because it destroys the size relationships in mitochondria that develop over time and it expands the morphology of mitochondria immediately.

The jab is capable of disconnecting the connections of water molecules in the subcutaneous fat regions which act to store protons and CO2 for later use in TCA cycle. This affects ATPase function. It has a direct effect on the quantum biology of DNA/RNA which alters the mitochondrial matrix directly.  Your mitochondrial defenses become worthless if there is no light in the UV and IR range to control the flow of H+ in its matrix.  This is the key metric to understanding the bio-physics of the cancer state when you have been jabbed.

PFIZER IS THE MOST WORRISOME FOR TURBO CANCER

The only reason to put a SV40 signal into the Pfizer jab, which was undisclosed to FDA, was to Genetically Modify people. A cursory review of the literature shows CRISPR CAS-9 uses it to enter the cell nucleus. If you remember my old webinars I told you I bio-hacked with CRISPR technology (in 2014) with disasterous results.

When you read the paper above one can easily come to the conclusion that it’s almost like they WANTED genome integration to cause disease in GMO humans they created. From my research it was their target vector. Destroying the gene pool is their intention to alter fertility and population density of humans. We have been invaded by these medical tyrants and no-one had to declare war – it’s done to many millions of people who complied with their wishes.

If you took the Pfizer jab you need to make oysters a staple of your diet. Why?

Oysters also lack an adaptive immune system as a filter feeder. Being filter feeder, they thus produce a diverse library of antivirals to complement their innate immune system. This can help slow viral actions inside of you. This paper will help make this case.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5869526/

Do I think the use of CBD should be encouraged for Pfizer patients?

Yes, I do based on papers I have read. Cannabigerol Triggers Cancer Cell Death in Pancreatic Tumours! The study found that CBG (Cannabigerol): Induces autophagy: This means CBG encourages the cells to “clean up” and recycle their own damaged parts, which can lead to the death of cancer cells. Reduces EGFR/AKT/RAS pathways: These are signalling pathways in cells that, when overly active, can lead to cancer growth. CBG seems to dial down these pathways, slowing or stopping cancer cell growth. Promotes apoptotic cell death: Apoptosis is the process of programmed cell death. CBG helps trigger this natural death process in cancer cells, effectively killing them off. Increases sensitivity to chemotherapy: This means that CBG makes pancreatic cancer cells (PDAC stands for pancreatic ductal adenocarcinoma) more responsive to chemotherapy drugs, potentially making treatments more effective. In essence, CBG shows promise in fighting pancreatic cancer by multiple mechanisms, making it potentially useful in combination with existing treatments.

LINK: https://www.mdpi.com/1422-0067/25/4/2001

Do I think we need to open up a Bitcoin fund raiser for PCR and sequencing of more tumor biopsies in the JABBED? I think we do. Kevin McKernan believes we should do this as well. If you took the Pfizer jab you must follow Kevin and Ethical skeptic on X.

Recently internal emails show the Australian drug regulator TGA knows DNA fragments in mRNA vaccines can enter the nucleus & integrate into the genome. The TGA withheld this info from the public, presenting a picture of certainty where there is none. You need to be aware of how dangerous these people are for your health.

TGA staff acknowledge DNA integration into the genome is possible: “Foreign DNA can integrate into chromosomal DNA in the absence of an integrase in mammalian cells.”

“The SV40 enhancer region can promote nuclear transport of DNA.” This is something that publicly the TGA assures can never happen.

Pfizer did not disclose the SV40 sequence to the TGA: “The plasmid also contains a SV40 promoter and f1 ori region (not shown in plasmid map presented by Sponsor but found in BLAST and reported in @DJSpeicher & @Kevin_McKernan papers).”

TGA insists that modRNA/DNA integration into human genome isn’t happening, but TGA staff are “unaware of studies which have tested this,” suggesting that the TGA is just making it up.

TGA staff admit that the modRNA vaccines with LNPs “have the potential to package non-target [ie: DNA] sequences and be administered to patients.” But the TGA still insists: “There is no significance to minute amounts of residual DNA being encapsulated in the LNPs.”

Throughout the 200 page discussion of residual DNA risks in the modRNA vaccines, the focus is entirely on “allaying fears in the public.” There is no contemplation of the theoretical risks discussed, which have not been clinically investigated.

The TGA had the gaul to say scientists spearheading the contamination issue internationally are not impressed.

“This is just overt smoke screening” –

@Kevin_McKernan

“Severe gaslighting, they are more concerned with maintaining the mantra of ‘safe and effective’” –

@DJSpeicher

You are being lead to slaughter folks by the government regulatory bodies because they do not even want you to know what they did to you. They want you to just accept the consequences.

The DoD and the CIA were exempted from these jabs. Both of them were distributors of the jab. As such they knew the real risks. Read the link below. It should make your blood boil.

https://x.com/dezzie_rezzie/status/1869680847428960458?twclid=2-6btsho7lm6qteul4bvhzi0xw0

Many people are searching the data and all are getting the same result. Helathy people are dying fast from turbo cancers.

THE BLOG TAKE HOME POINT:  What is the take home of all this work? COVID 19 hijacks your ATP synthesis, drains the Mitochondria of its ability to transform energy via ATP as it replicates to the highest copy number transcript in the cell. When you understand this point, you will understand why tropical sun is the best antidote because UVA light does the same thing by turning off ATP and UVB light turns on production of NK cells to deal with cancer by creating them from T-regulator cells.

SUMMARY

DO YOU REMEMBER WHEN THE WEF TOLD YOU THE PLAN RIGHT OUT IN THE OPEN?

My bet is you do not. This paper was from a long time ago.

“Klaus Schwab will bioengineer humans into short infertile vegans to stop Climate Change”

Remember when they told us “Covid Vaccines don’t change your DNA, they aren’t Gene Therapy.”

They are. Where did the idea come from? An NYU Chinese WEF member.

Look at the archived post. It should really open your eyes. https://archive.ph/KCFvb

CITES

https://www.rebelnews.com/science_confirms_sv40_dna_in_pfizer_s_covid_shot_validating_concerns_over_unexplored_genetic_health_risks

The  skill is most needed times of stress is to learn which questions are unanswerable, and not to answer them.

Before you begin here click on this link and let it play before you read a word.

HYPERLINK

Now listen for two to three minutes with your eyes closed before you begin to open your present.

Never begin with certainties, because, if you do, your experiences shall end in doubts. Always hang a question mark on the things you have long taken for granted in your “Matrix of beliefs.”

Question every axiom you were taught.

The antonym certainty isn’t uncertainty. It’s openness, curiosity and a willingness to embrace paradox, rather than choose up sides.

We sometimes FEEL that we are right. But weI do not KNOW that we are and this propels the mind to continuously move foward

Permanent, intolerable uncertainty is what makes life worth living.  The zest in life is created by not knowing what comes next.

Humans don’t ultimately crave power. They crave certainty, because they never have it. The more power someone has the more uncertainties they face…

The more desperately they need someone who appears to have answers.

The most wise among us embrace uncertainty. Some of the most beautiful chapters in our lives shouldn’t have a title until we live out our time.  Reflection provides that much later.

What I want for my tribe to rebuild their ability to think.  I want them to crave first principles as the cornerstone of their regeneration.

Our reality is that the drive beneath every hope, dream, and action is that we all desire well-being.

Some cultures, like the French, scoff at happiness. They say, “Don’t impose on us the dirty work of happiness.”

Pleasure is fleeting, but happiness is a state of being. Pleasure is a chocolate cake – delicious at first but sickening by the third slice. Happiness is the ocean depths – serene and untouched by passing waves.

Happiness is an inside job. We dedicate years to education and fitness. But the most important training is often neglected: mastering our minds.  This is my superpower. I have dedicated my life to my mind and its ability to think and reason.  Most people dedicate their lives to vanity and the facades we see in life.  I want to worship the things found in the deepest darkest places in our minds.

Mastering our mind is the one task that determines the texture of our entire lives.  When you meet someone who has cultivated the garden of their mind you will find a human who is happy in their own skin.  They appear to be calm in any storm.

If you are deeply unhappy within, all you are going to look for is a window from which to jump. We grasp for it in external conditions, but our control over them is limited. The mind is the true translator. We chase happiness in all the wrong places.

The key to happiness lies in the quality of our thoughts and the contentment of our mind.

Mind transformation – that is the very meaning of meditation. It’s a skill, not a luxury. The quality of every moment depends on the state of our minds. Yet we spend so little time tending to it.

The nature of the human mind is pure awareness, not permanently stained by destructive emotions. Through meditation, we can train the mind, transforming it at the deepest level. Opposite mental states cannot coexist.

Why is the mind important.  When you face adversity or an adversary explain to them that their mind is on a sliding scale that ranges from ignorance to fraud.  Ask them where the line between both ideas in their own mind.  It will uncover much about the uncertainity of the situation.

Ignorance more frequently begets confidence than does knowledge: it is those who know little, not those who know much, who so positively assert that this or that problem will never be solved by science.  They ask to rely on transparency instead of focusing on the data sitting right in front of them.

Decentralized science proves meditation’s power for humanity.  Mitochondriacs with 10,000+ hours of practice show vastly increased activity in brain regions linked to happiness and compassion. They learn to become fire breathers and put those with unsettled thinking into chaos.  This is done to show them that their thinking is disordered inside the storm.  To become well, the storm should not affect the mind.  In fact, the mind should feed off the storm.  They demonstrate superhuman emotional control inside themselves. What they show the world externally is a facade of who they are inside their own storm.  Mind training shapes the very structure of our grey matter in our neocortex.

The experience that translates everything on Earth is within the mind. Circumstances are the waves. The mind is the ocean. Will you be tossed by every passing swell? Or will you dive deep and discover the stillness within?

At the core of all well-founded belief lies belief that is unfounded. If those around you are locked into concrete thinking you must free yourself from their bonds. Sovereignty is the right to tell those you love and care about that you have the right to tell them things that they do not want to hear.

To break free from the past, you must first acknowledge its existence. You don’t have to be defined by your past. You can be shaped by it, but you can’t let it define you.

The moment you decide to break free, you reclaim your power & sovereignty.

SUMMARY

Happiness is not the absence of suffering; it is the ability to deal with it.  Compassion is not just a wish to see others free from suffering; it is a willingness to take action to alleviate their suffering.  The more we care for the happiness of others, the greater our own sense of well-being becomes.  This is the essence of the decentralized clinicians mindset for his tribe.  Happiness is not a destination to be reached; it is a way of traveling on our thought through our own mind.

When we open our mind to the suffering of others, we discover a profound interconnectedness that transcends boundaries.  Those connections always link to the threads Nature weaves for us.  My job as a clincian is to reconnect your mind back to that source code.

Happiness is not something that can be pursued; it is a state of mind that arises from within Nature’s threads.  My wish for you this Christmas is that you realize these lessons and do something in 2025 to cultivate your mind better than you have previously.  And when you do this, you should then re-gift it to the people who matter to you in the coming years.

The happiest people don’t have the best of everything; they make the best of every storm they experience. Please learn to train your mind to think this way.

Mitochondrial success isn’t about medical predictions. It’s about having:

• An unflappable system with a verified edge: Nature

• Unwavering discipline to execute it

• Mental framework to stay objective

The world’s top decentralized thinkers understand this fundamental truth.

You will not break loose until you realize that you yourself forge the chains that bind you. The world we are about to enter requires this realization.

Merry Christmas and Happy Holidays.

For the first time, graphene has been successfully converted into a unique state of topological insulator. Graphene, a two-dimensional material with a single atomic layer composed only of carbon, has attracted attention as a next-generation electronic device material because of its high thermal and electric conductivity. Carbon, in this form, acts like a metal.

Graphene has other queer properties. It is not sensitive to time. The time-reversal invariant 2D topological insulators are also known as the quantum spin Hall effect (QSHE).  A physical system is time reversal invariant if the underlying laws are not sensitive to the direction of time. There are various accounts of time reversal transformation, resulting in different views on whether or not a given theory in physics is time reversal invariant.

However, graphene is useless for many photonic and electronic applications because it is too conductive and has no band gap.

The band gap is a fundamental property of a semiconductor because it determines its color and conductivity.

COLOR

A painter’s palette is rich with colors, some arising from the band gaps in natural semiconductors.

The mechanism behind the color we perceive in semiconductors can be explained by the band theory that governs color in many metals. Like metals, semiconductors have a reflective surface when polished but do not conduct electricity as effectively. Semiconductors frequently act as insulators and require particular conditions to become conductors. While metals become more resistant to the flow of charge with increasing temperature, semiconductors become conductors only with sufficient thermal energy, performing better as temperature increases.  Water does this as well because it is also a semiconductor.  It becomes more quantum coherent when light strikes it to form coherent domains.

If the substance has a large band gap, such as the 5.4 eV of diamond or the similar value of corundum, then no light in the visible spectrum can be absorbed. These substances transmit all incident light and are colorless in their pure forms. In their powdered forms, or when their structure prevents light from being transmitted, all light is reflected to the observer, and we see them as white. Such “large band gap semiconductors” are excellent insulators and behave like covalently bonded materials.

If a pigment can absorb all wavelengths, we see it as black, just as we see most metals as black in their powdered form. A white pigment absorbs no visible light. As in subtractive color mixing, we see its complementary color when a specific wavelength is absorbed from incident white light.

I mentioned this here: VIDEO

A “medium band gap semiconductor” is a material with a somewhat smaller band gap, such as the compound cadmium sulfide (CdS). This is the pigment cadmium yellow, known as the mineral greenockite (more examples in table).

This change in the band gap size is illustrated using mixed crystals of yellow cadmium sulfide (CdS, Eg = 2.6 eV) and black cadmium selenide (CdSe, Eg = 1 .6 eV), which have the same structure and form a solid-solution series. The photograph above illustrates the yellow-orange-red-black sequence of these mixed crystals as the band-gap energy decreases.

Mixed crystals such as cadmium sulfoselenide (Cd4SSe3) form the painter’s pigment cadmium orange and are also used to color glass and plastic. Mercuric sulfide (HgS) exists in two different crystalline forms. Cinnabar (the pigment vermillion) with Eg = 2.0 eV is a deep red but can transform upon exposure to light in an improperly formulated paint to the black metacinnabar with Eg = 1.6 eV in as little as five years; this has happened in several old paintings.

Another method of manipulating the color of semiconductor materials is by adding impurities. These doped semiconductors have energy levels within the band gap and allow us to tailor the wavelength of emitted light. Some semiconductors contain impurities in their natural state, providing useful insights into these behaviors.

CONDUCTIVITY

A band gap prevents short circuits since the electrons aren’t continuously in the conduction band. A small band gap allows the solid to have a strong enough flow of electrons from the valence to conduction bands to have some conductivity. So graphene would constantly short out, which is why adding graphene to the human system is a problem.

If the band gap is too high, most daylight photons cannot be absorbed; if it is too low, then most photons have much more energy than necessary to excite electrons across the band gap, and the rest is wasted.

A band gap is the distance between the valence band of electrons and the conduction band (see the picture above). Essentially, the band gap represents the minimum energy required to excite an electron to a state in the conduction band where it can participate in conduction.

Graphene’s basic properties show for the first time that electrons in a non-metal appear like a metal, and it can behave like a fluid.  Not having a band gap makes it unique.  Metals tend not to have band gaps, either.

In ordinary, three-dimensional metals, electrons hardly interact with each other. However, graphene’s two-dimensional honeycomb structure acts like an electron superhighway in which all the particles have to travel in the same lane. The electrons in graphene act like massless relativistic objects, some with a positive charge and some with a negative charge. They move at incredible speed — 1/300 of the speed of light — and have been predicted to collide with each other ten trillion times a second at room temperature.  These intense interactions between charge particles have never been observed in an ordinary metal.

Life uses carbon, just not in graphene form. When you have a material that’s one atom thick, it’s going to be really affected by its environment. Life cannot have a detector that is this sensitive because there is no way to control the signal well without large external electric and magnetic fields.

If the graphene is on top of something rough and disordered, it will interfere with how the electrons move in that substance. It’s essential to create graphene with no interference from its environment.

Quantum mechanics describes very small things, like electrons, while relativistic physics, pioneered by Albert Einstein, describes very large and very fast things, like galaxies.

Linking classical hydrodynamics theories with Einstein’s theories of relativity can describe high-energy systems like supernovas and black holes.

But it’s challenging to run an experiment on a black hole. Enter graphene.  When an electric field drove the strongly interacting particles in graphene, they behaved not like individual particles but like a fluid that hydrodynamics could describe.  Instead of watching how a single particle was affected by an electric or thermal force, we could see the conserved energy as it flowed across many particles, like a wave through water.

We discovered physics by studying black holes and string theory, which we see in graphene.  This is the first model system of relativistic hydrodynamics in a metal.  Life is based on low-energy physics systems at a small scale. Quantum mechanics rules that domain.   A small graphene chip can be used to model the fluid-like behavior of other high-energy systems found in galaxies and black holes.  Einstein’s relativity rules high energy systems.

Materials conduct heat in two ways: through vibrations in the atomic structure or lattice and carried by the electrons themselves.  Science has needed to find a clever way to ignore the heat transfer from the lattice and focus only on how much heat the electrons carry.  To do so, the researchers turned to noise. At finite temperatures, the electrons move about randomly:  the higher the temperature, the noisier the electrons. By measuring the temperature of the electrons to three decimal points, researchers were able to measure the thermal conductivity of the electrons precisely.  Converting thermal energy into electric currents and vice versa is notoriously complex with ordinary materials.  But in principle, with a clean graphene sample, there may be no limit to how good a device you could make.

SUMMARY

I have a sense that we might be able to cure people using this TI and high-intensity light in combination, but we will have to test the theory.

The material’s band gap is determined by its molecular structure; semiconductors’ periodic, crystalline atomic structure gives their valence electrons the ability to become conductive at specific temperatures.  Carbon on the periodic table has many atomic crystalline forms.  For example, as a diamond, its molecular arrangement gives it a large band gap and can act like a semiconductor.  Graphene is also a crystalline form of carbon, and it has no band gap and acts like a metal.  All living things are carbon-based, but our atomic arrangement is between diamonds and graphene.

This explains why the atomic structure inside your cells is exact and why the jabs were a problem because of the 51 elements they all contained.

Photosynthesis uses visible light to separate water.  To effectively utilize visible light for water splitting, the typical band gap of the semiconductor should lie within the range of 2.0 to 3.0 eV.

Visible light covers the range of approximately 390-700 nm, or 1.8-3.1 eV.

Viktor Schauberger found in water what modern-day physicists are finding out about graphene. Both are fluids that can act like metals when environmental conditions are just right.  What does this finding really imply to humans who observe nature well? This means that low-energy small-scale systems like cells and high-energy systems like CERN use physics very differently than the low-end system in mitochondria, which is quantum-based.  High-end energy systems on a large scale are relativity-based.  People don’t realize that semiconductors act by paying attention to the local environment……..it happens with graphene, and it happens with DHA.  Water and graphene have something else in common.  They are both semiconductors in specific environments.  Semiconductors are antennae for electromagnetic radiations; the thinner they are, the better the antenna is at receiving electromagnetic signals from outside.

Could a neurotropic virus disrupt the main semiconductor system in our brain to alter it?  We’ve seen Zika and Covid clearly do that.  I believe the mRNA jabs do this as well. DHA and water are where it all begins in the brain.

Energy expenditure is all tied to cerebral blood flow (CBF) and cerebral metabolic oxygen consumption (CMRO2).  Is it possible that a virus could alter the brain, causing microcephaly today?  Yep…….So, shrinking cerebral tissue reduces brain volume, improving CBF to CMRO2.  This saves energy when the environment is not ideal.  Might there be a reason Zika, autism, Alzheimer’s, and ALS have all shown up out of the blue?  Might it be why all the post-COVID complications have shown up as well? I think so.

Might that reason be a lack of energy from mitochondria?  Yep.  When a semiconductor senses electromagnetically, there is not that much energy to draw from it, and it shrinks in kind thermodynamically to adjust.  That saves massive energy.  The modern world has created an ionosphere filled with nnEMF and blue light.   Might these two things be linked in some way no one is making sense of?  Yes, I think so………

CITES
https://www.science.org/doi/10.1126/science.aad0343

This might be the most important video you will watch today.

This excerpts from my 2017 Vermont talk laying out how light/EMF controls everything in biology. Credits to “Video Advice” on YouTube.

We think Homo sapiens came into existence around 200,000-300,000 years ago in equatorial Africa based on varying data. Two hundred thousand years is a long time, and it’s a complex number to fathom. So, let’s convert that considerable, unfathomable number into something we can all understand. How about a single calendar year? To put 200,000 years of human evolution onto a calendar year scale, we first need to determine how long an actual calendar year would be on that scale. Here’s how the math works: One year is 365 days; 365 days is 8,760 hours; 8,760 hours is 525,600 minutes; and 525,600 minutes is 31,536,000 seconds. When we divide 31,536,000 seconds by 200,000 years, we determine that an actual calendar year passes by in 158 seconds, or two minutes and 38 seconds, on our scaled calendar year.

A decade is over in 1,577 seconds, or 26 minutes and 47 seconds. A century is complete in four hours, 22 minutes, 48 seconds. And so on. Now that we understand these numbers, we can put significant events in human history on our calendar year timeline. The first one is easy: Our species came into existence in Africa 200,000 years ago, at midnight on January 1. Humans first migrated out of Africa 70,000- 100,000 years ago—give or take—which is July 1 on our timeline. Let that sink in for a moment: For half of our existence as a species, we lived in, or very near, Africa. Modern humans entered Europe about 40,000 years ago.

That event occurred at midnight on October 20 of our calendar year timeline, when 80 percent of our species’ existence was over. It’s incredible how time relativity works, isn’t it, when you think about how humans and time are related? Archaeologists agree that agriculture joined our technological repertoire about 12,000 years ago in the Middle East. That’s December 10 at 2:24 a.m. on our calendar year timeline. The Industrial Revolution, a decades-long technological transition that ushers in, or at least makes possible, the modern era, occurs in the early afternoon hours of New Year’s Eve. Consider the implications of that fact: 99.9 percent of our species’ existence is over before we enter a technological context that is even remotely close to modern. But if you think about it, the Industrial Revolution is archaic compared to today!

No plastics. No cars. No television. No radio. No telephones, much fewer smartphones. The Industrial Revolution marks the beginning of a remarkably different era for us as a species, yet it occurred during the last 0.1 percent of our time on this planet. Wow! What about the iPhone? It shows up on our timeline at 11:31 p.m. on New Year’s Eve, within the last half-hour of our calendar year timeline.

People like Casey Means want you to believe that using nnEMF to monitor your blood glucose is better than how your brain does it. If you think I am kidding, look at this paper below. It should now be clear that, when examined from this perspective, humankind’s relationship with technology, with change, and with time is in uncharted territory for our CIRCADIAN BIOLOGY. The risks for man so far have exceeded the promise of productivity…………..in my estimation.

SUMMARY

Casey Means thinks a cell phone app is good for monitoring blood glucose and insulin. Look at the pictures to see how FLAWED this idea is. Trotsky’s granddaughter, Nora Volkow, who runs the National Institutes of Drug Abuse, wrote this paper a decade before Casey Means started using a cell phone app to monitor blood glucose.

Pardon me if I think she LEARNED nothing at Stanford University about doing research.

I think she learned to do this from Anne Wojcicki at 23andMe when she was married to Google’s Sergey Brin. Trotsky’s granddaughter, Nora Volkow, who runs the National Institutes of Drug Abuse, wrote this paper a decade before Casey Means started using a cell phone app to monitor blood glucose.

LEVELS technology is PSEUDOSCIENCE, and PEER REVIEWED SCIENCE ABOVE IT SHOWS IT.

CITES

1. https://pubmed.ncbi.nlm.nih.gov/21343580/

Every sunrise at the beach is a growing heat like a million blazing suns all focused on my mind. It lights my pilot light to warm my insides to conquer another day.

Chaos answers the question humans have posed for millennia, how did we get here?

In life, as everywhere in the cosmos, there exists a struggle between matter, both biotic and abiotic.   Chaos is entropy in abiotic systems (represented by fear in biotic systems) and order is a zero entropy state of life (represented by curious exploration in biotic systems).

Everything that is abiotic dies in “heat death”.  What we fail to realize today in biology is that biological order comes out of this chaos.  Chaos seems to the biologist to be a world described as we understand a heat engine in which heat is converted into motion only at the price of irreversible waste & useless dissipation.

TIME STAMPING

TIMING CONTROLS HOW ENERGY FLOWS IN CELLS. This is why time stamping by the circadian mechanism is the cornerstone of decentralized health. Biotic atoms must be time stamped to avoid chaos.

What is the human time stamping mechanism?

CLOCK and BMAL1 are positive regulators of circadian gene expression, and PER and CRY are the NEGATIVE FEEDBACK LOOP regulators that operate under day and night cycles. These are the positive and negative feedback arms of the circadian mechanism.

Ilya Prigogine defined dissipative structures and their role in thermodynamic systems far from equilibrium, a discovery that won him the Nobel Prize in Chemistry in 1977. Simply stated any dissiptive structure has to time stamp atoms in some way to avoid the chaos of heat death. In summary, Ilya Prigogine discovered that the importation and dissipation of energy into chemical systems could result in the emergence of new structures, which became known as dissipative structures, due to internal self-reorganization. In his 1955 text, Prigogine drew connections between dissipative structures and the Rayleigh-Bénard instability, and the Turing mechanism. Prigogine’s theorem is germane to these ideas. As such mitochondria should be thought of as time stamping machines at the core of cells.

Ilya Prigogine defined dissipative structures and their role in thermodynamic systems far from equilibrium, a discovery that won him the Nobel Prize in Chemistry in 1977. Simply stated any dissiptive structure has to time stamp atoms in some way to avoid the chaos of heat death. In summary, Ilya Prigogine discovered that the importation and dissipation of energy into chemical systems could result in the emergence of new structures, which became known as dissipative structures, due to internal self-reorganization. In his 1955 text, Prigogine drew connections between dissipative structures and the Rayleigh-Bénard instability, and the Turing mechanism. Prigogine’s theorem is germane to these ideas. As such mitochondria should be thought of as time stamping machines at the core of cells.

SUMMARY

The dynamic, energetic closure of the living system proposed built by Nature in cells gives rise to a number of important consequences. First and foremost, it frees the organism from the immediate constraints of energy conservation — the first law of thermodynamics — as well as the second law of thermodynamics, thus offering a solution to the enigma of the organism posed by Lord Kelvin and Schrödinger.

Because of the atomic organization of cells (AMO physics) there is always energy available within the cellular system. The energy derived from the sun is stored coherently in many places in cells, and ready for use, over all space-time domains. Mitochondrial water production is critical in the blueprint because it stores more light energy to use for TIME STAMPING. This picture shows that relationship CLEARLY

The fidelity of this water creation is the basis of the autonomy of organisms. Organisms are never simply at the mercy of their environments on account of the coherent energy stored. When the environment steals this ability from cells (nnEMF) cells are at the mercy of food and exercise.

More to the point, we don’t have to eat constantly (Leptin Rx), leaving plenty of time for other useful, pleasurable activities (SEX). This is why food is not the top of list of worries.

The other consequences are that the organism is exquisitely sensitive and free from the mechanical constraints of life on Earth; and satisfies, at least, some of the basic conditions for quantum coherence. Water creation by mtDNA provides that as well.

According to Ilya Prigogine, determinism loses its explanatory power in the face of irreversibility and instability in dissipative systems. This is a major departure from the approach of Newton, Einstein and Schrödinger, all of whom expressed their theories in terms of deterministic equations.

Indeterminism is the opposite of determinism and is related to chance. Chance is related to probability. In science, most specifically quantum theory in physics links directly to probability and not cause and effect. Indeterminism is the belief that no event is certain and the entire outcome of anything is probabilistic. Heisenberg’s uncertainty principle and the “Born rule“, proposed by Max Born, are often starting points in support of the indeterministic nature of the universe. Indeterminism is also asserted by Sir Arthur Eddington and Murray Gell-Mann. Indeterminism has been promoted by the French biologist Jacques Monod‘s essay “Chance and Necessity“. Ilya Prigogine argued for indeterminism in complex systems.

At life’s genesis chaos has to gain order. Dissipative structure theory really aims to solve this problem for biology by using physics.

Man has lost his humility with progress.  Humility is simply nature’s disposition that prepares our minds for living on intuition.  Nature’s disruption is what human life should rely upon. This process is controlled by sunlight and should be uncontrolled by man.  Manmade light has usurped this process.  This has allowed our brain to become preoccupied with technological progress which is now leading to biological disruption.

CITES

https://www.youtube.com/watch?v=jtMu-KFyKxM

https://forum.jackkruse.com/threads/mitochondrial-thermodynamics-diy-lesson-thread.27408/

If you are following the series, you will see the story of light stress, which was used in an adaptive fashion by mammals 65 million years ago to survive.  What underpins this effect, however, may shock you.  It is POMC.  It turns out that repeated exposure to low levels of mitochondrial stress, which environmental light induces, and various cytosolic and nuclear responses build resilience against higher levels of stress. This response would have significantly benefited mammals during an extinction-level event. This adaptive response, primarily known as mitohormesis, has been shown to extend health span and/or lifespan in several model organisms (Yun and Finkel, 2014).

What are the consequences here?

Ancient adaptions can lead to modern diseases when the spectrum of light changes again.  Remember, the initial adaptation mammals made was due to a lack of UV light in their environment, and they ran predominantly from 390nm to -3100 nm.

Today, centralized medicine looks at hemochromatosis as a disease when, in reality, it occurred as an epigenetic adaptation for an iron protection strategy that humans used to keep adult males alive to reproduce to allow them to survive in Europe for the last 1000 years.  Today, scientists are beginning to realize that our ‘junk DNA’ seems to be the raw material for constructing new wide-bandgap (WBG) semiconductors that use light to sculpt changes.  This is how our semiconductors transform light into epigenetic information to change the game so survival is guaranteed.   Evolution seems to tell us that in the last 1000 years, biology built a new way to defend against pathogens and events we have recently faced so that we can survive whatever life throws at us. This semiconductive fabrication plant in our bodies (POMC) acts like an evolutionary junkyard that allows us to innovate new novel ways to survive a bad event.

We now know that transgenerational epigenetics in the Viking men of the Northern coastline of Northern Europe was selected for hemochromatosis.  We believe that the COLD, harsh Tundra of the north was mineral deficient. Women with this genetic defect would have fared as better child bearers because they could absorb more iron to birth more children who also carried the hemochromatosis defect into the next generation.  It is also believed that the Viking men might have survived the disease because their Gladiator-type lifestyle was ferocious, and they often faced severe blood loss that might have offset the iron defect.  As Vikings settled in Northern Europe, the mutation grew using the “founders effect” caused by inbreeding due to small population sizes.  The founder effect means that any ‘non-lethal defects’ are highly selected for and carried in the entire population of a people.  It is believed that the ‘Viking defect’ was blended into the populations of Northern and Western Europe over 500 years to solve the recurrent Yersina outbreaks that caused the bubonic plague and almost extinguished humans in Europe.  The chronicity of the infection was an ‘epigenetic signal phenomenon’ that allowed for the selection of the hemochromatosis gene to confer reproductive fitness over longevity. At the same time, the Yersina remained active in the human population.  This remained true for close to 500-1000 years.

This “irony” may now explain why ancient physicians were barbers and bloodletters. We used to believe this practice was ‘quackery,’ but we now know that it was the survival of the wisest in action. Bloodletting had a significant role in conferring more longevity to those with hemochromatosis of European descent. When you bleed, you release a massive dose of vasopressin from the posterior pituitary.

Until the 20th century, bloodletting was standard practice. Then, it was stopped, and hemochromatosis became a modern disease. Canadian physiologist Norman Kasting found that bloodletting also released the hormone vasopressin (ADH) from the posterior pituitary. This release from the hypothalamus reduced their fevers and increased their immune function to act faster to save them. This finding was not causation, but the correlation between bloodletting and fever reduction is massive in human history. Bleeding them down may have helped fight infection when it was present.  When we bleed, vasopressin release is also altered. nnEMF does the same.

AUTOIMMUNITY AND VASOPRESSIN

Abnormal non-circadian release of vasopressin is linked to autoimmune conditions in modern man.

The arginine vasopressin hormone (AVP) of the posterior pituitary increases blood−brain barrier permeability. It also affects voltage gates and water balance in cells.

The immune system (IS) plays a vital role in protecting our body and can recognize its tissues from foreign molecules. The IS comprises lymphoid organs, cellular components, humoral factors, chemokines, and cytokines that respond to antigens that can harm the body (Shinde and Kurhekar, 2018; Verbsky and Routes, 2018).

The IS is highly and tightly regulated by mtDNA signaling and biophoton biology; however, its disruption could induce diverse pathological disorders, such as allergies and asthma; subsequently, when the host’s tolerance is exceeded, the condition becomes an autoimmune disease (Anaya et al., 2016).

nnEMF exposure is critical to BBB function, as Russ Adey and Allen Frey demonstrated in the 1960s.

Most autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, Hashimoto’s thyroiditis, Crohn’s disease, type 1 diabetes mellitus, and MS are considered chronic illnesses today by centralized medicine. I consider them modern diseases linked to aberrant lighting and nnEMFs.

Some of them can induce neuroinflammatory and neurodegenerative processes in the CNS, which occur when the integrity of the BBB is compromised, as the pictures above show. The BBB is considered a highly selective barrier between the cerebral capillary blood and interstitial fluid of the CNS (Kadry et al., 2020; Schreiner et al., 2022) and helps keep harmful substances from reaching the brain as pathogens, toxins, and some drugs, as well as prevents the entry of IS components (Daneman, 2012; Kadry et al., 2020; Knudsen et al., 2022).

The principal constituent of the BBB is the endothelial cells, which provide protection and structural stability to the blood vessels on tight junctions (the liner sheets pericytes and astrocytes that ensheath the blood vessels and restrict the substances entering the brain or its immune system. The breakdown of the BBB promotes its permeability, permitting the entrance of immune molecules and lymphocytes, inducing autoreactive conditions in the blood-spinal cord barrier and BBB; as a consequence, damage and destruction of the myelin sheath increases, causing neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, ALS, and MS.

Similarly, neuroinflammation promotes the entry of IS components through the BBB and blood-spinal cord barrier into the CNS; therefore, an increase in the barriers’ permeability induces the interaction of pro-inflammatory cytokines such as the interleukins 1β and 17A (IL-1β and IL-17A), and tumor necrosis factor α (TNFα), which activates the downregulation of tight junctions in the endothelial cell barriers. IL-17A has been associated with the loosening of both obstacles, as shown by in vivo and in vitro assays. It is related to the production of reactive oxygen species by nicotinamide adenine dinucleotide phosphate (NADPH) and xanthine oxidase action, which are related to increasing in the endothelial cells’ permeability, causing a decrease in the occluding protein, zonula occludens-1 in in-vitro assays by Arima et al., 2013. The photoswitch I have mentioned before is a critical circadian controller of the ROS mechanism.

In contrast, the hyperactivity of sensitized lymphocytes induces the proliferation and secretion of IL-17 in MS. In addition, under normal conditions, T regulatory (Treg) cells alter and break down the balance in IS responses, which are accompanied by MS (Pot et al., 2011). Immune cells such as T and B lymphocytes, macrophages, and innate immune cells promote the disease’s pathophysiology. Myelin antibodies from B cells induce the loss of the myelin sheath. Furthermore, studies have demonstrated the presence of immunoglobulins IgG and IgM in patients with acute and chronic MS.

THESE DISEASES ARE MULTIFACTORIAL, BUT LIGHT AND POMC DYSREGULATION ALWAYS AT THE CORE

The human hypothalamus is a pivotal governing center for various metabolic processes in the body (Roh et al., 2016; Waterson and Horvath, 2015). Proopiomelanocortin (POMC)-producing neurons in the hypothalamic arcuate nucleus (ARH) are critical in regulating energy and water balance. (below)

POMC neuronal activity is strongly tied to mitochondrial function.  The higher your mitochondrial redox power is on your inner mitochondrial membrane, the more POMC a tissue will express.  More POMC = more semiconductors can be made.   POMC neuronal activity can be upregulated in mice by mitochondrial-derived ROS (Diano et al., 2011). Moreover, mitochondrial dynamics (i.e., fusion and fission) in POMC neurons are essential for maintaining whole-body energy and glucose homeostasis under altered metabolic conditions (Ramírez et al., 2017; Santoro et al., 2017) in all mammals. Despite the evident importance of mitochondria-originated signals in POMC neurons (Mishra et al., 2014), the details of the underlying mechanisms remain largely unknown in centralized medical research.

MITOCHONDRIAC UNDERSTANDING:  SUNLIGHT IS MANDATORY for making water at CCO during the day in mammals. If you do not get enough sun or live at a high latitude inside all day, you need more water to avoid the vasopressin release issued POMC.  If we do not get enough sunlight, we’re dehydrated, and then we lose circadian feedback control of vasopressin, and the entire water cycle in our body goes awry. This facilitates the development of autoimmunity.

This is how lousy clock management leads to epigenetic disease by decreasing mitochondrial redox power.  This is why big pharma is now pushing the use of anti-vasopressin analogs for MS patients.  Understanding POMC is understanding modern human neolithic diseases.  Mammals are creatures sculpted by light.

Recent work in this area shows that POMC neurons exhibit a dimorphic (biphasic) response to mitoribosomal stress in a dose-dependent manner; homozygous deletion of Crif1 was detrimental (i.e., severe light stress), whereas heterozygous disruption was beneficial (i.e., mild light stress).

How does IR-A light work in the sun?  A biphasic dose response has been frequently observed where low levels of red light have a much better effect on stimulating and repairing tissues than higher levels of light. The so-called Arndt-Schulz curve is commonly used to describe this biphasic dose response.  Centralized medicine has no idea how POMC works with light. POMC gets cleaved using the biphasic actions in light.  When cleavage is imprecise, disease results. Now you do, too.

Published research has found that low levels of mitoribosomal stress in POMC neurons induced high metabolic turnover and resistance to obesity through cell-non-autonomous mitochondrial stress signaling between the hypothalamus and adipose tissues.  That stress signal is VUV light emission in hypothalamic neurons in the leptin-melanocortin pathway.  That is how you stay thin.  It would be best to renovate the melanin sheets inside your tissues constantly.

In humans, prolonged or repeated cold exposure without surface-level UV light can increase the mass and activity of brown adipose tissue in the neck and supraclavicular regions, as defined by the uptake of glucose, and can improve glucose homeostasis. This is the off switch for ACTH release from POMC mammals used to survive in high latitude and poorly lit cold areas.

POMC neurons control adipose tissue thermogenesis (Dodd et al., 2015).  I knew 15 years ago that this discovery, as pictured below, was coming.  Brown adipose tissue works its job because of melanin.  Surprise!

Mitochondrial communication via optical transmission is the key to adaptive stress response following mitochondrial perturbation. Recently, small functional peptides encoded within the mtDNA, known as mitochondrial-derived peptides (MDPs), have been identified (Reynolds et al., 2020). MDPs represent a unique class of mitochondrial-encoded signaling factors that respond to mitochondrial stress and promote health/longevity (Galluzzi et al., 2018; Mottis et al., 2019; Quirós et al., 2016; Tan and Finkel, 2020).

Notably, MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) mediates mitonuclear communication by translocating to the nucleus upon metabolic stress and regulating adaptive nuclear gene expression to promote cellular homeostasis (Kim et al., 2018).

Light sculpts your life.  VUV light, to be exact, when it comes to autoimmune disease conversion. That tells me that mtDNA biophoton release is where the defect is because terrestrial sunlight does not contain these frequencies.

Vasopressin (AVP) is a crucial hormone regulating water balance and is released during hyperosmolality to limit renal excretion.  It has a long history to explore.   It is produced by adjacent melanin in humans. Arginine-vasopressin (AVP) is a nonapeptide that is synthesized mainly in the supraoptic (SON), paraventricular (PVN), and suprachiasmatic nucleus of the hypothalamus. In addition, AVP is produced in several other brain areas and organs, e.g., the medial amygdala, bed nucleus of stria terminalis (BNST), and the adrenal gland chromaffin cells. Its release is associated with any body stress response, opening the blood barriers to the gut and brain.

SUMMARY

When vasopressin is altered, so is iron biology, which leads to an altered amount of ROS/RNS. Why?

Re-read this blog. It tells you how light and ROS are linked.   https://www.patreon.com/posts/quantum-75-p53-106441242

Why do we say oxygen is “reduced” when iron is oxidized in our body?

We say this because iron has gone from its elemental state with no charge ( Fe0) to its ionic state (Fe3+). Because the iron has lost electrons and become positively charged, it has been oxidized. The oxygen has been reduced because it gained the electrons iron donated to it. The electrons from the iron went to the oxygen. Every oxidation process has to have a corresponding reduction.

Iron exists predominantly in two biologically relevant redox states: ferric iron, the oxidized state (Fe3+), and ferrous iron, the reduced state (Fe2+). Fe2+ is well known to facilitate electron transfer reactions that can lead to the generation of reactive oxygen species.

The involvement of singlet oxygen in biophoton emission has implications for our understanding of many diseases like mast cell disease in the skin that links to immune function. Mast cell dysfunction is related to an absence of 1270 nm light in the skin of mammals. Singlet oxygen is known to liberate this frequency of light, as the picture in this blog shows. People with mast cell disorders do not make enough hydrogen peroxide from their mitochondrial respiration. As a result, a comorbid lack of sunlight containing 1270 nm light and lack of H202 creation in tissues is associated with immune dysfunction in mast cells. There is a lesson here that the photoswitch in our cells is teaching us about immune dysregulation.

People with autoimmunity, mastocytosis, and poor wound healing are always deficient in AM sunlight. Why? This is when we get a lot of NIR light with 1270 nm. Early morning sunlight, 6 AM -9 AM, has a relative irradiance with a higher amount of photons in the visible and NIR spectrum than midday exposure (noon). The picture tells why decentralized medicine always recommends AM sunlight. This sun time = TINA = THERE IS NO ALTERNATIVE.

CITES

G.T. Dodd, S. Decherf, K. Loh, S.E. Simonds, F. Wiede, E. Balland, T.L. Merry, H.Münzberg, Z.Y. Zhang, B.B. Kahn, et al.  Leptin and insulin act on POMC neurons to promote the browning of white fat.

Alvarez, J. I., Cayrol, R., and Prat, A. (2011). Disruption of central nervous system barriers in multiple sclerosis. Biochim. Biophys. Acta BBA – Mol. Basis Dis. 1812, 252–264. doi: 10.1016/j.bbadis.2010.06.017

Anaya, J.-M., Ramirez-Santana, C., Alzate, M. A., Molano-Gonzalez, N., and Rojas-Villarraga, A. (2016). The autoimmune ecology. Front. Immunol. 7:139. doi: 10.3389/fimmu.2016.00139

Arima, Y., Kamimura, D., Sabharwal, L., Yamada, M., Bando, H., Ogura, H., et al. (2013). Regulation of immune cell infiltration into the CNS by regional neural inputs explained by the gate theory. Med. Inflamm. 2013:898165. doi: 10.1155/2013/898165

ASTELLAS Pharma US, Inc. (2005). Vaprisol (conivaptan hydrochloride) injection. Rockville, MD: Department of Health and Human Services. Available online at: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2005/021697s000_Vaprisol_Approv.pdf

Baron, J. L., Madri, J. A., Ruddle, N. H., Hashim, G., and Janeway, C. A. (1993). Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177, 57–68. doi: 10.1084/jem.177.1.57

Tissue atrophy and inflammation in retina cells in the far periphery of the retina were most predictive of cognitive status, the study found.  This is where the iPRGCs of melanopsin are located. https://lakegenevanews.net/lifestyles/health-med-fit/alzheimers-first-signs-may-appear-in-your-eyes-study-finds/article_91986868-0e1a-5002-80d2-29bd618e20a9.html

Microglial cells declined by 80% in those with cognitive issues, the study found.  POMc is located in microglial cells.

RPE cells are located between photoreceptor cells and the choroid membrane, with the basal side connected to Bruch’s membrane and tip microvilli connected to the outer segment of photoreceptor cells (Figure 1).

Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no curative therapy for these disorders.  The reason for this belief is because modern medicine has no idea that renovating POMC internally by improving mitochondrial redox power and optimizing hemoglobin delvery is the key to RPE repair.

Light in our environment plays the most dominent role in obesity. The slide below shows how badly the food gurus have missed the boat.

Within the central nervous system, energy homeostasis is largely controlled by a fine balance between orexigenic and anorexigenic neuropeptides in the hypothalamic arcuate nucleus (ARC). Neuropeptide Y (NPY) and Agouti-related protein (AgRP) are coexpressed in neurons of the ARC and are potent orexigenic peptides, whereas proopiomelanocortin (POMC) precursor protein in the ARC is cleaved into potent anorexigenic α-melanocyte-stimulating hormone peptides. NPY/AgRP and POMC neurons in the ARC are considered “first-order” sensory neurons in the control of energy homeostasis (1) and receive, coordinate, and respond to changes in nutrient and hormonal fluctuations associated with changes in metabolic status. NPY acts on Y1 and Y5 receptors in the paraventricular nucleus of the hypothalamus to stimulate feeding, whereas acetylated α-melanocyte-stimulating hormone and AgRP peptides act as agonists and antagonists, respectively, at the melanocortin 4 receptor (MC4R). The POMC and AgRP interaction at the MC4R is collectively known as the melanocortin circuit. The critical importance of the melanocortin system in food intake and energy balance is highlighted by conditional gene ablation experiments. Ablation of POMC neurons in adulthood produced an increase in food intake and body weight and caused glucose intolerance, whereas ablation of AgRP resulted in rapid hypophagia, weight loss, and starvation = anorexia

Where the defect is on the retina and skin determines whether you get obesity or anorexia. We see this in drug addicts, alcoholics, and we see it in anorexics who live inside behind glass and infront of sceens. Both conditions, however, are associated with altered signaling in the leptin melanocortin pathways.

Why did obesity really happen dramatically after 1874 when the power grid was begun? LIGHT. It brought us INSIDE where the PROBLEM was.

When we started plugging in to the AC power all hell broke loose and this is where MOST chronic disease epidemics began. HARD STOP

Governments allowed NGOs like Gates and dermatologists began to advocate blocking the sun while putting screens in front of millions of humans from 1947 on. In 2009 Barry Obama and Biden changed FCC broadcast transmission from analog to digital and this brought LCD and plasma screens. Now LCD screen make up 99% of screens. All screens default setting out of a FACTORY ARE SET to blue frequencies. THIS MAKES YOU MORE COMPLIANT TO GOVERNMENT PROGRAMMING. The evolutionary time line of light makes this abundantly clear. Food gurus like the MEANS SIBLINGS are like propaganda wings of the Federal government who are now weaponizing MKULTRA programming at GLOBAL SCALE. They are paid by a16z who is a Silicon Valley investment group who supports Big Tech where all blue light begins.

THIS WAS THE GOAL OF MKULTRA —-> https://www.youtube.com/watch?v=SiBFtwbyv44

In 2007 Barry Obama said we are also going to remove incandescents which contain some UV and IR. the government knew what they were doing. They knew it make you more susceptible to things coming from Wuhan. They told us that it was to lower energy bills. That was a PR bullshit story that the media sold and then the food gurus were weaponized like legacy media reporters to repeat the liwe so you’d all believe it. AND 99% of you have.

They did it to lower our dopamine levels to make us more responsive to the political moves. This also lowered out melatonin levels simultaneously and this is why all kids now get Rx for melatonin from pediatricians who are complicit in the chronic disease epidemics. When dopamine and melatonin drops SO DOES POMC TRANSLATION. This means melanin never gets made properly. THAT IS WHERE YOUR DISEASE EPIDEMICS COME FROM.

Mental disease, drug addiction and obesity all come from obstruction of this pathway by modern lighting. LOOK AT THE PICK ABOVE. YOU ARE BEING LIED TO IN A BIG WAY by the NGO and Government partners in BigHarma and Big Tech that both sit at the CANTILLON EFFECT. Calley and CASEY MEANS ARE PAID BY THESE PEOPLE and this is why both of them have companies that use WBAN technology which MAKES YOU SICK. They got this idea from the Wojcicki sisters of YT and 23andme and YT and Google’s Sergei Brin. See this here to show the PROOF —–> https://threadreaderapp.com/thread/1826512218088722575.htmlXIA

THE DRUG ADDICT STORY BELOW LINKS TO WHY SOME GET ANOREXIA.

SUMMARY

In the leptin melanocortin system of the retinohypothalmic tracts in the eye the, hormones of the “fed state” such as leptin and insulin, are released in the bloodstream by adipocytes and by the β-cells of the pancreas, respectively, cross the blood-brain barrier to bind to leptin and insulin receptors on the surface of pro-opiomelanocortin (POMC) neurons to promote processing of POMC to the mature hormone α-melanocyte-stimulating hormone (α-MSH), which signals to decrease energy intake.

The three MSH molecules from proopiomelanocortin (POMC) decrease appetite, increase satiety, and increase energy expenditure:

• Alpha-melanocyte stimulating hormone (α-MSH)

  A POMC-derived neuropeptide that binds to melanocortin-4 receptor (MC4R) in the brain to suppress appetite and increase energy expenditure

• Melanocortin-4 receptor (MC4R)

  A receptor expressed by neurons in the paraventricular nucleus (PVN) that suppresses food intake when bound to α-MSH

• POMC neurons

  Neurons in the hypothalamus that produce α-MSH and other peptides that act on MC4R-expressing cells

Leptin and serotonin are signals that promote POMC neuron action, which leads to the production and release of α-MSH. In contrast, ghrelin is an orexigenic hormone that activates AgRP neurons, which antagonize MC4R signaling and increase food intake.

Mutations in the POMC gene have been linked to severe childhood obesity.

STOP LETTING THEM LIE TO YOU.

IT ALL BEGINS WITH LIGHT

CITES

Zarbin M. (2016). Cell-Based Therapy for Degenerative Retinal Disease. Trends Mol. Med.22 (2), 115–134. 10.1016/j.molmed.2015.12.007

Tian X., Cui Z., Liu S., Zhou J., Cui R. (2021). Melanosome Transport and Regulation in Development and Disease. Pharmacol. Ther. 219, 107707. 10.1016/j.pharmthera.2020.107707

https://threadreaderapp.com/thread/1826512218088722575.html

Robert O. Becker, MD, found that some part of matter in our nervous system created a DC electric current, and that current drove all healing and regeneration. That current also broke with convention because it could de-differentiate RBCs to primative forms to create stem cells to regenerate our tissues. The current needed was precise. One-thousandth of a million ampere of current was required to do this. Anything less or more than this was a problem. This was the electromagnetic criticality that mammals needed for well-being. When I met Becker in 2007, I told him that POMC was the source of his work. Light was the source of man’s regenerative current. This idea was more heterodox than his journey into bone regeneration.

The phenomenon of criticality has been postulated to explain the sudden emergence of new properties in a wide range of complex systems, from avalanches to flocks of birds to stock market crashes. I believe it is behind the modern epidemics of autism and neurodegeneration, too. I think it is exacerbated by things that reduce our redox potential, like vaccines and modern lighting. Neuroscientists are now seeking evidence that criticality is at work in the brain’s networks of neurons.

Criticality is linked to how the OPN5 melanopsin receptor works in the human brain. It is the critical opsin that defines modern chronic diseases.

I believe self-organizing criticality theory (SOC) needs to critically look at the work of Ilya Prigogine on how dissipative systems operate.  I believe this is why SOC is stuck in the mud with neuroscientists.  To understand this idea you need to understand how the liberation of Vitamin A from our non-visual photoreceptors begins the process of diseases by destroying all of our photoreceptors.

People often forget that all of the cytochrome proteins in our mitochondria are also heme-based photoreceptors linked to this damage cascade. This is found in every human disease I have studied, from autism and Alzheimer’s to zoonosis.

All mitochondria liberate heat. and melatonin and water  Heat is linked to universality and universality is linked to the fractal design found in nature.

Joseph Fourier made an essential contribution to physics in the nineteenth century when he published his mathematical formulation of how heat propagates. Today, Fourier’s law tells us that heat flows from regions of higher temperature to areas of lower: “that heat flux is proportional to the difference in temperature.” This law is a remarkable insight into universality. Here, we have many disparate macroscopic systems, from solids to gasses to liquids, each containing an inordinate sum of molecules and conforming to a heat conductivity law. To the chemist Ilya Prigogine, Fourier’s description was the “birth of the science of complexity.”

Around the same time, another universality, the first law of thermodynamics, was formalizing in science. It tells us that while “energy cannot be created or destroyed, it can be transferred from one form to another. Energy is forever conserved in the universe.

The critical phenomenon of nature is how light energy is transformed.  It can become mechanical, chemical, or vital energy (DC electric current). Light energy undergoes a continual conversion of itself as it interacts with matter.  The atomic organization of matter is the key to energy transformation and criticality.  This energy attraction occurs throughout space and drives the living force in cells. The energy flow is called kinetic energy, which drives heat into one form of energy or another. Thus, order is maintained in the universe—concerning the total energy in the system, nothing is deranged, and nothing is ever lost. Still, the entire machinery in cells, as complicated as it is, works smoothly and harmoniously.

I believe sleep is designed to get brains back to the SUBcritical state, but electromagnetic signaling from circadian biology is what is required to optimize electromagnetic criticality in neurons.  This electromagnetic criticality is linked to the optimized control of ALL charged particles in the entire system.  This creates the quantum coherent state in cells.  Normally, mitochondria set the system close to the subcritical tone of the system, but light sets off the criticality.

Order Comes Out of Chaos

Everything not alive dies in “heat death”.  Order always arises out of environmental chaos.  It’s a world described as an engine in which heat is converted into motion only at the price of irreversible waste & useless dissipation.

So energy all goes from one conversion to another and tends toward a final state of thermal equilibrium = ‘heat death.’  Life uses cells to slow this “heat death” by slowing the flow of entropy by arranging atoms ideally in cells.  The cell is a dissipative structure that controls the flow of energy so that it can be transformed many more times into useful work.  This is the basis of why critical points are needed in Nature’s biological machines inside of cells.

An isolated system is on an inexorable track toward equilibrium, but many interesting things can happen in between. Life at equilibrium is called rigor mortis.  Time spent in a far-from-equilibrium state is called life.  Health is the slowest form of death we can create with our choices around light.

In health, solar energy is pumped into cells and stored, and entropy decreases. This is the blueprint of how all living dissipative structures operate.  The sun is itself a dissipative structure.  So is the Parker spiral.  It is the heliocentric magnetic sheet that engulfs the entire solar system.  This magnetic sheet in the solar wind affects all living things on Earth via their mitochondria.  This is partly how our brains remain subcritical at the proper times.  Sunlight alters our tissues to induce changes in our charge density.  In animals, electrical information generated in mitochondria is more crucial than genes that form tissues, but few people realize this today in centralized science. It turns out that charge density variation by moving electrons around our tissues is the key to understanding what life is up to when it is connected to the decentralized energy systems of Nature.  That is how super-criticality is found during the living state.

WHAT DOES LIFE LOOK LIKE WHEN IT RESIDES ABOVE OR BELOW THIS CRITICAL POINT?

Diseases are processes associated with chronic energy loss and entropy gain. The causes can be vast, but the endpoint is always the same.

When life is lived below the critical point for any reason, heteroplasmy rates expand in those tissues until energy flow ceases, organ failure takes over, and death is invited to your life.

Earthian life is an open system—doing as much as it can with the solar energy it receives from our aging Sun. The living cell represents an incessant metabolic activity, where thousands of chemical reactions take place simultaneously.

Fasting Factoid:  Is fasting tied to a solar mechanism related to iron hemoglobin?  Before you answer, think about these facts about fasting.  The blood diminishes in volume in proportion to the decrease in the size of the body during a fast so that the relative blood volume remains practically unchanged during a fast. The quality of the blood cells and plasma is not impaired; indeed, an actual rejuvenation of the blood may occur if that blood is allowed to touch the rays of the sun because of how porphyrins work with sunlight.

The old literature on fasting has pointed out that the first effect of a fast is to increase the number of red blood corpuscles.  This increase is an acute phase change only and improves the quantum yield if the blood is allowed to be irradiated by sunlight.  If the fast goes too long, the spleen acts to decrease the RBC’s mass.  When this happens, the astute clinician should expect mitochondria in tissues with high heteroplasmy rates to lose more energy and enlarge as things do when they lose energy (think heart failure or a dying star).  The acute increase of erythrocytes during the early part of the fast should be regarded as an improved flow of energy from mitochondria due to autophagy and a cessation of overeating. This red blood cell mass increase has been repeatedly observed in acute anemia cases throughout 20th- 21st century medicine. The decrease in RBC mass is only observed after the starvation period is reached.  What are the implications of this, and how might we mito-hack this with new devices that could take advantage of this unique aspect of RBC mass?

When humans are sleep deprived or suffering a circadian mismatch, their brains become supercritical, although a good night’s sleep can move them back toward the critical point. It thus appears that brains naturally incline themselves to operate near this critical point,  This points out why sunrise every AM is critical to resetting the critical point in the brain every day. POMC activation is the key to regeneration.

The miracle of our brain’s physiology isn’t that you can see the world as it is. It’s that you can see the world as it isn’t. My job is to explain what you can’t see, but physics has been observed to exist. The absence of evidence in a biology book is not an absence of effect in nature.

The claim that the cortex operates near the critical point is a sweeping one, encompassing optimal information processing, neurological health, and a nearly universal application across species. The need for strong scrutiny is not surprising.

So, why is this view of the critical brain still just a hypothesis? While the evidence in its favor is good, it’s still under discussion.

Early critiques pointed out that proving a network was near the critical point required improved statistical tests. The field responded constructively, and this type of objection is rarely heard these days. More recently, some work has shown that what was previously considered a signature of criticality might also be the result of random processes. Researchers are still investigating that possibility, but many of them have already proposed new criteria for distinguishing between the apparent criticality of random noise and the true criticality of collective interactions among neurons.

Meanwhile, over the past 20 years, research in this area has steadily become more visible. The breadth of methods being used to assess it has also grown. The biggest questions now focus on how operating near the critical point affects cognition and how external inputs can drive a network to move around the critical point. Ideas about criticality have also begun to spread beyond neuroscience.

Citing some of the original papers on criticality in living neural networks, engineers have shown that self-organized networks of atomic switches can be made to operate near the critical point so that they compute many functions optimally. The deep learning community has also begun to study whether operating near the critical point improves artificial neural networks.

SUMMARY

Dreams seem natural when we are in them, but it is when we wake up that they begin to seem strange to us.  Might this be evidence of how a point of criticality operates in the mammalian neural network?  At the critical point of CNS, fluid acts as a single phase of matter. These fluids are both liquid and gas in quality. These fluids are highly compressible at a critical point, and they allow for travel into other dimensions of the mammalian network.  Here are some other significant ideas linked to this story. POMC is required with mtDNA water to create the DC current of Becker. This is the critical point you need to acquire in your journey of wellness.

https://twitter.com/DrJackKruse/status/1680466637827235845

CITES

https://www.jneurosci.org/content/31/1/55.full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665287/

https://www.nature.com/articles/nphys1803

https://www.sciencedirect.com/science/article/pii/S0896627319307378

https://www.sciencedirect.com/science/article/pii/S0896627319309596

https://www.sciencedirect.com/science/article/pii/S0753332223000756