I was just out in Malibu with Mr. Rubin and one of his friends, interviewing me for a movie we are making about me and Quantum Biology. We sat down two days ago and did a three-hour podcast that will be part 3 of the Tetragrammaton series. The goal of part 3 is to go deeper into the implications of what was said between Rick, Huberman, and me. Part 3 was done without Andrew. Bill Gifford sat in his place, and he is an award-winning health journalist.
SO WHAT DID WE TALK ABOUT?
Can we see the evidence of light toxicity in the skin before it afflicts the brain? Yes, we can. People often forget that the skin and brain come from the same tissue layers in the human embryo. Because of this linkage, your skin and your eyes tell your decentralized physician to look deeper into your health to see how badly you are afflicted with light toxicity. See this thread and read my comments for the details. HYPERLINK
Do you know the implications of the last post above about breast cancer and Vitamin D and sulfation? What happens when you add sunlight to a skin? Melanin becomes eumelanin because of the addition of the sun. Did your experts know that? Did you see the color of all human hair, skin, and eyes is made from this sulfated semiconductor? Do your experts know how this all works in the human mammal? I’m just warming up, folks.
What makes melanins so unique and so attractive to science these days?
The list of arguments is a long one. From the viewpoint of physicochemical properties, all melanins share:
(a) a broadband absorption spanning the entire spectral range of the visible domain
(b) a permanent electron paramagnetic resonance (EPR)d signal denoting a stable paramagnetic character.
An unpaired electron can change its electron spin by either absorbing or emitting a photon of energy, denoted by hv, such that the resonance condition, hv = the change in Energy is obeyed. This leads to the fundamental equation of EPR spectroscopy.
Electron Paramagnetic Resonance (EPR) is the study of direct transitions between the electronic Zeeman levels of the ground state. EPR is a magnetic resonance method under suitable microwave stimulation, enabling the unpaired electrons by their magnetic moment. The basic concepts of EPR are analogous to those of nuclear magnetic resonance (NMR), but the spins excited are those of the electrons instead of the atomic nuclei.
(c) hydration-dependent semiconductor-like behavior. For example, eumelanin conductivity increases in water because it conducts electricity via ions and electrons.
(d) efficient dissipation of electromagnetic energy as heat. Melanins can absorb massive amounts of light and get rid of it quickly without damage to the system. Water with a high dielectric constant helps facilitate this.
On the chemical side, most melanins display:
(a) antioxidant properties, both as an H-atom donor and as a reducing agent;
(b) metal chelation and binding of organic compounds
(c) redox behavior.
In addition, melanins are bioavailable, biocompatible, and biodegradable, thus representing the most promising candidates for biomedical applications in optical signaling in the condensed matter physics world of science.
Melanin has many of the same semiconductive abilities we see in cytochrome c oxidase, which is also a semiconductive protein (above). That protein is responsible for water creation in the mitochondrial matrix. Water creation and alteration by the mitochondrial matrix is how the DC electric current is stepped down to the precise amperage to create the regenerative drafts used in mammalian tissue regeneration found by Robert O. Becker’s experiments..
Melanin is the critical tissue in all mammals. It allows for tissue engineering and regeneration via nanotechnology operations in the cell via a combined diagnosis and therapy (theranostics) action with our stem cell supply. Melanins are also critical in creating the bio-photon spectrum needed to run the specificity of biomolecules in the cellular system of control. The source of the electromagnetic wave spectrum has to match the absorption spectra of biomolecules to keep the system far from equilibrium so coherence and entanglement are possible.
WHAT IS INFLAMMATION IN THE MAMMALS FUNDAMENTALLY?
It is from a lack of sun or too much light at night. This is the primary decentralized cycle in all of biology.
Eumelanin is a form of melanin and conducts electricity – albeit weakly – in its natural state. Researchers first discovered that the polyindolic pigment was a semiconductor in the 1970sand suggested that this behavior comes from energy bands associated with a non-localized empty molecular orbital within the eumelanin polymer chain. All free radicals are paramagnetic because they have unpaired electrons. So are all the melanins in mammals. This makes them the ideal wide band gapped (WBG) semiconductor to absorb them. This again points out how modern biology is lost in the woods. They believe ROS/RNS is terrible when, in fact, they are critical in how non-linear optical signaling controls biochemistry in cells by creating the right spectrum in bio-photon release from tissue-level metabolism controlled by mitochondria. When melanin is missing, chaos in tissues is created = inflammation. That is how inflammation manifests in you and every mammal on this planet. This is how modern neolithic disease is being made in the USA at alarming rates.
So, my patrons, I hope you are beginning to see why Nature wants to limit deuterium in the mitochondrial matrix now. Could its carburetor function be linked to water chemistry that is quantized to the amount and spectral density of biophoton release in the matrix by metabolism?
I think so.
A lack of POMC, degraded melanin, and a matrix not making water is all a sign of a mammal in deep need of the sun to begin its melanin renovation Rx.
Well, it turns out that deuterium in the mitochondrial matrix is controlled differently in every body tissue because each tissue needs a specific regenerative current to differentiate stem cells to rebuild tissues anew.
The reason is simple: deuterium concentration allowed into the mitochondrial matrix is how a cell controls metabolic rates in different tissues. No two tissues have the same physiology. Therefore, metabolic rates have to vary in these tissues to be thermodynamically efficient. This creates the spectrum of the VUV-IR-A light used to manage the biochemistry in that specific tissue. Not all tissues have the same metabolic rates because of their physiologic needs. This means the metabolism of a mitochondrion produces its unique spectra. A unique spectrum means the matter in these tissues must also have individual absorption spectra. This should raise the question, how does the matrix in differing tissues get more deuterium? What type of WBG semiconductors should we expect there? What is the gating mechanism?
The answer is the type of melanin adjacent to the uncoupling proteins of mitochondria that generate heat from metabolism. Remember, all haplotypes produce varying amounts of heat via uncoupling efficiency. The thermodynamics here are also linked to how badly degraded the melanin is in the tissue system. A big clue to this mystery is if ROS/RNS production is driving biomolecules of inflammation higher or lower: HS CRP, haptoglobin, homocysteine, lowered glutathione, procalcitonin, etc. This heat is liberated into the surrounding water to dampen the current in the electrical conduction pathways found in cells.
The recently released Owen Sheasby podcast illuminated this effect.
The further one goes from the equator; the more uncoupling humans need to use to control the regeneration current in a tight ampere range. Equatorial light is the most powerful light on Earth, and this is the light human mammals evolved under. That system is a powerful melanin stimulus for the skin. At higher latitudes, cold temperatures stimulate more robust frequency endogenous light generation. Moreover, as a result, more heat is produced, and melanin in our interiors becomes a better electrical conductor. Any excess heat is thermalized directly to water so the system can remain far from equilibrium. The slide at the beginning of this blog post shows this effect.
The closer the equator one lives, the less uncoupling one needs because the sun provides all the ingredients for self-regulated autophagy and apoptosis, which is controlled by ferroelectric currents in the cell that are dampened by melanin biology. Why is ferroelectricity the key to this process?
Iron’s toxicity is mediated by sunlight, and few people seem aware of it. Please recall the first steps of heme synthesis in mammals begin in the mitochondria. This was proven by papers from Simcox JA, Mitchell TC, Gao Y, et al. In Rubin, Kruse, Huberman Part 1 & @ I told you hemoglobin was the second big innovation in evolution after chlorophyll.
Heme synthesis begins its first step in mitochondria. If you have a circadian mismatch disease tied to melanopsin dysfunction by definition you are blue light toxic or nnEMF toxic and this causes a defect in mitophagy and ruins the iron cycle in humans. This immediately affects the liver clocks, too. This leads to fatty liver disease.
People in centralized healthcare often forget heme synthesis occurs partly in the mitochondria and partly in the cytoplasm. This is precisely how the TCA and urea cycle are built in us too. The process begins in the mitochondria because one of the precursors is found only there. Since this reaction is regulated in part by the concentration of heme, the final step (which produces the heme) is also mitochondrial.
People with defects in iron always have a blood dyscrasia (anemia) at some level and it usually bleeds into fertility and thyroid hormone creation too, because of its link to AM sunlight deficiency. These pathways are proximal to the melanin-building pathways as the slide shows below. In Part 3, I get into it with Bill about how melanin degradation and bleeds backward into this pathway via hypoxia. This is a catabolic effect All nnEMF cause hypoxia in humans and drives this catabolism of endogenous melanin to lead to interior destruction and a lack of wound healing.
Remember, purple light = UV light and it creates oxygen in our venous blood and this drives anabolic pathways to make melanin via POMC and alpha MSH.
Purple light in sunlight ALSO stimulates RBC synthesis in humans. Blue light causes RBCs to break down sooner and live a shorter life than they can. What is the color of the main breakdown color of heme? It is the complementary yellow color of bilirubin. Yellow is the complement of purple, and orange is the complement of blue in the color wheel.
An analogy to explain this idea is how paragliders use the thermals on Mount Blanc to ride high up into the atmosphere. The sun heats the air at the mountain’s base, and the heat rises to carry the gliders to very high altitudes. This allows them to ride the thermals almost at no energy cost. The only price needed is the solar input that drives the temperature variations. If you were a glider who wanted to go further than anyone else has ever gone, you’d need to add an engine to your back that could work to power a fan to move you further. If you did this, you’d have to have a solution for the altitude problem. Why? As we go higher, oxygen is not as expected, and neither is temperature. This is why the circadian mechanism measures them in their optical lattice clock mechanism. I explained this to Mr. Sheasby in his podcast and the Tetragrammaton part 3 podcast. This is why the human retina consumes more oxygen than any tissue in the human body. Modern eye researchers and clinicians do not explain why the choriocapillaris does what it does. I realized it immediately as the source of why obesity happens when the periphery of the retina is destroyed by blue light. This also occurs when melanopsin is at its highest density in human tissues. The choroid sits adjacent to the retinal pigmentum epithelium on its densely fenestrated side to act like a radiator to absorb heat. A thickening of the choroid is the first sign of impending obesity in humans (Pics below). BOOM
This also explains why fat people now have lousy bones and why the mechanical stress of weight no longer makes Wolf’s law factual in centralized biology.
Metabolomics network studies show that the kinetic isotope effect (KIE) of deuterium affects the metabolism of L-lysine, L-glutamine, and L-serine. This is why linoleic acid loaded with deuterium affects bone metabolism at its core. Pass that fact on to the food gurus. They remain ignorant of biophysics. Be careful who packs your parachute, folks.
As such, you’d need a mechanism to alter the fuel and oxygen mix to be oxidized to power your flight. This is very similar to what a car has to do with its carburetor. The higher you go, the more pseudohypoxic you get, so you must alter the fuel source to maintain your flight. The third through fifth citations below highlight this.
Mitochondria are hydrogen-fueled engines, so deuterium concentration and production is critical in biology. This explains the title of this paper. Deuterium-depleted water stimulates GLUT4 translocation in the presence of insulin, which leads to decreased blood glucose concentration. I still chuckle at the food gurus ranting about seed oils and never realizing they are deuterium bombs. https://pubmed.ncbi.nlm.nih.gov/34510301/
The UCP-2 proteins were innovated for this reason. It controls the fuel-oxygen mix in mitochondria. It is a carburator for deuterium/H+ flow. The more deuterium that flows in, the more anions in the TCA cycle are bound to the substrates because of the kinetic isotope effect (KIE) of deuterium. One deuteron binds 96 H+ protons in the matrix. This slows the spin rate of the TCA cycle. That has an indirect effect of raising and lowering methionine in its metabolic cycle, causing a collection of heavy metals. This is how melanin detoxes heavy metals and does not use endogenous glutathione. When someone has heavy metal toxicity, it is a sign to me, as a decentralized clinician, that they have a vast POMC problem and they need more sunlight to renovate melanin inside the affected tissue. Chelating with exogenous agents is a losing strategy of functional medicine. The reason it’s so popular is because of the revenue it generates.
SUMMARY
How do you know your clinician is genuinely a decentralized mitochondriac? The whole world will tell you they are nuts, and you should not follow what they tell you. Be wise enough to know that the paradigm does not like truth-tellers. They are bad for business.
Is melanin a perovskite material with unique biophysical abilities that centralized biology has ignored at your peril? You bet your ass it is. What else doesn’t centralized science know? Biophysics controls all the biochemistry in their books. If you do not understand what light is doing you don’t understand decentralized biochemistry either. They are light ignorant. Biomacromolecular pigments, such as melanin, play an essential role in the survival of all living beings as I told Rick and Andrew. Melanin absorbs sunlight transforms it into heat and deposits the energy in water and proteins at the electronic level to build a dissipative system. This step is crucial for avoiding damage to skin cells. Light absorption produces excited electrons, which could either fall back to ground states by releasing the heat (photothermal effect) and/or light (photoluminescence), or stay at higher energy levels within its lifetime period, which can be captured through external electronic circuitry (photovoltaic effect). In published studies that no one in centralized biology reads, it has been demonstrated that the combination of melanin with halide perovskite light absorber in the form of a composite exhibits high absorbance from the UV to NIR region in the solar spectrum. And the hybrid displays significantly reduced photoluminescence and minimized density of residual excited states (verified by photovoltaic measurement) owing to the enhanced considerably nonradiant quenching by the melanin.
As a result, the composite shows an ultrahigh solar-thermal quantum yield of 99.56% and solar-thermal conversion efficiency of ≈81% under one-sun illumination (AM1.5), which is superior to typical carbon materials such as graphene (≈70%). By coating the photothermal composite film on the hot side of thermoelectric devices, a 7000% increase in output power as compared to the blank device under illumination is observed. Mammals are experts in collecting the sun using this technology woven into the fabric of NATURE. Get your skin in the game of the sun.
Please remember blue light induces hypoxia in cells, and this stimulus causes melanin to break down into L-DOPA, dopamine, adrenalin, and noradrenaline. Every biochemistry textbook printed has this pathway, but most centralized PhDs and clinicians have no idea how it links to melanin biology. How much crowd wisdom is there when most of the crowd is afflicted by nnEMF and blue light, and their frontal lobes have been emptied of melanin/L-DOPA/dopamine anyway?
Did you know that cephalopod ink is 70% pure melanin? Do you know why? https://www.youtube.com/watch?v=ohZsX5-qAD0
More sun = more water production by the mitochondrial matrix = more mitochondrial melatonin production = less chance of leptin resistance = less chance of neolithic disease. Any light at night causes leptin resistance = Blue light at night is the worst offender = because it makes melatonin vanish = causing leptin resistance = mitochondriac, and melanopsin wisdom and proves the food guru fail……
LIGHT’S EFFECT > FOOD EFFECT
All food is, at its core is matter created downstream from sunlight—photosynthesis wisdom on display. When the world moves away from your biological necessities, becoming fearful is fruitless. That’s not the point, given the dire situation. It’s learning how to control your fear, harness it, and use it as fuel to change your conditions of existence. Fear shouldn’t shut us down; it should wake us up to increase the fidelity of our awareness and focus to overcome the present challenge we face and crush it.
Stand for what is right even if you are standing alone. There is a fine line between challenging yourself and overwhelming yourself. Changing paradigms is not for the weak of heart or mind. This type of transformation takes hold of you. Invades you. Soon it owns you. You want to be free of them, but you never will be. A prolonged movement on the right way is better than overwhelming speed on the wrong path, and this is why you enjoy the chaos of being overwhelmed. You must become the change you seek in this world now.
Part 3 of Tetragrammaton is epic. I hope you all enjoy it once Mr. Rubin is done editing it.
HAPPY HALLOWEEN!
CITES
1. Pullman, A., and Pullman, B. (1961). The band structure of melanins. Biochim. Biophys. Acta. 54, 384–385. doi: 10.1016/0006-3002(61)90389-4
2. https://www.popsci.com/eumelanin-conduct-electricity/
3. https://www.sciencedirect.com/science/article/abs/pii/S0166432821004861
4. https://www.frontiersin.org/articles/10.3389/fendo.2022.927576/full
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881424/
6. https://twitter.com/DrJackKruse/status/1718950743674163200