Month: November 2020

Strong network effects are at the core of every platform technology business.  All of them employ algorithms to drive their success or failure.  70% of enterprise value is locked up in these network effects.  A network effect increases the value of the company or currency as new people join the platform and it expands its influence.  For example, in the game Monopoly, once enough properties are owned by a single player, renters can’t afford to pay rents and are therefore forced into bankruptcy – and the game ends.

For those who have played, you will notice how systems work. ie – Once you have an early advantage, the game becomes easier (because you have the rents) to acquire more properties, add more houses/hotels.  A “positive feedback loop” is created – concentrating wealth.  This idea built into the fabric of the game explains to you why TIMING matters most in economic  It turns out in a technocracy platform 42% of enterprise value comes from having good timing.  Bill Gross of Idealab did a TED talk on this in 2015.  Listen to what he said about timing.

HYPERLINK

In the Monopoly board game, you might also notice that the wealth in the game “might” be due to luck – landing on the right squares early in the game gives you a massive advantage. Right place right time really matters.

Conversely, missing out on acquiring those assets early creates a “negative feedback loop” which also reinforces on itself. The poor become poorer until they become insolvent as they move around the board paying higher and higher rents.  The result become inevitable as they bleed all their cash reserves.

Fortunately – it is just a game. The game ends! Someone gets bragging rights – and all are given a fresh chance to “win” when the game begins anew with everyone being equal.

BUT- What would happen if the same positive and negative feedback loops happened in real life? With the “winners”  acquiring ever more because they had the assets first- concentrating their wealth, and enjoying privileged access to the best education, medical, and other services.

This brings us to the topic of the blog, is BTC the vaccine for COVID?   What if I told you COVID narrative is just political cover for a coming economic disaster.  This is why the government wants control of the education system to keep us financially illiterate.

Timing is of the essence right now with BTC to help yourself before you are drowning.  What is the time to get into BTC?  You want to have a colonial position  before all the network effects I mentioned to you above occur fully. Right now three things are the wind in the sails of BTC timing.  Politics, COVID 19, and the coming economic storm.  Right now most of the public and investing world are sleeping on the enterprise value of BTC as a a new currency as these macro effects are occurring in our lives.   Are consumers ready for a currency that holds its value while jobs are lost to technology platforms?  No, I don’t believe they understand its real value because the events of economic destruction are not obvious to 99% of the public yet.  Does our current money system allow us to be prepared for what is the collateral effects?  No, it was built for another world and different form of government.

The exact same playbook is now occurring to the US Federal reserve.   I want you to think of the US Fed as Blockbuster in this example.    It has been the only money game in town since WW2 because of the Bretton Woods agreement I mentioned earlier in this series.  The American government feels omnipotent when it comes to its currency, because in 1971, its own president decided to break the agreement unilaterally and move our currency off the gold standard.  Nixon did this to stimulate the economy to get him a second term in 1972.  That single action actually exploded into the financial crisis of 2008 under the regimes of Bush and Obama.

The key to their success is their business plan and the algorithms they use to remain stealth.  New companies are always underestimates the older companies because the older companies have spent decades at perfecting their own blue print to gain market share.  They develop a business myopia.  Sometimes, the old companies know what the deal is but their business model does not offer them the ability to compete as the market shifts.  This is how Blockbuster lost out to Netflix over night when I was a resident in the late 1990s

Nixon’s decision was fueled by economists who convinced him that easy credit and debt would help stimulate a faltering economy that occurred during the late 60s and early 1970s when food and gas prices spiked very quickly.  This threatened his re-election.  In an interconnected economy driven by credit and debt there are some longer range macroeconomic pitfalls.  In 2008, Bush and Obama had to decide what was more important, banks or the people?  They both chose to bail the banks out.  When you bail out the banks and risk takers in this economic model the collateral effect is that you create a moral hazard by eliminating trust from the public.  All paper money is a trust agreement between its people and its government.  Since 2008, that trust is worse because it has created the greatest wealth disparitiy the US has ever faced.  This includes the era of the “robber barons” of Rockefeller, Carnegie, and JP Morgan that Teddy Roosevelt broke up in his presidency.  The reason the two leaders chose banks over the public was because if they did not act this way,  they risked a world wide depression that likely would have dwarfed the 1929 Great Depression.  This is why they did what they did.  Why do I rehash it for you here?  Because it sets the stage for optimal timing now with respect to BTC and when you should buy it.

When someone asks me the Question now: “Should I buy BITCOIN now?

My answer is now: “Is it under $100k per coin?” –  If so, the answer is yes you should be a buyer.  If it is not you need to do more homework because the network effects mentioned above are likely taken effect.

Negative interest rates is a death sentence for all macroeconomic trends and it will destroy the economy quickly because it is the thing that will cause central bank death quickly.  Why?  You will have to pay the bank money to keep your money in the bank and banks will struggle to find dollars in this situation.  Study the slide below to understand these implications.

The quick death of prolonged negative interest rates will allow new ideas to take over even faster than anyone imagines.  The printing of money is a sign the patient is critically ill and we all need to become prepared for the inevitable at some time.  This gives us time to make ready how we will respond.  It also gives new technology companies and public entrepreneurs the time to create a new options to run an economic system.  That is what BTC fundamentally is for us all.  The US Federal reserve has no idea this is what it is but CEOs of at least 16 companies now see the handwriting on the wall.  All of their corporate money is now being stored in Bitcoin.  The charge is being lead by Micheal Saylor the CEO of Microstrategy.  I believe that when macroecononmics dies a slow or fast death, equities, countries, and people who put BTC in their treasuries into BTC will be able to force the US Federal Reserve to use Bitcoin as its new currency to avoid a revolutionary war.

It took Bitcoin 12 years to build an impenetrable store of value and in this scenario the Federal Researve will have no time to build their own to control it because the economic storm the lockdowns of COVID have caused cannot be solved with old tools.  Moreover, no one will ever trust the Federal Reserve again after this event.  I see the change will be lead by CEOs who had the foresight to see this tsunami coming.  The US Fed and Gold market have no idea what to make of BTC.  In this analogy, the US Federal Reserve is Blockbuster and they are staring at Netflix just shrugging it off.   Do not let their mistake be your mistake.  You might survive but you won’t thrive.

BTC is a lot like Facebook and Amazon in their early days.  They bring immense value to the user via their platform.  Network effects are at the core of what creates their value.  The same is true for BTC.  the issue is the network effects of BTC have not yet taken hold.  Why do I think now is the time for BTC?

The financial crisis of 2007–2008 was a symptom to the Black Swan that the Central Banks all over the world had a viral illness.  The doctors who should have regulated the system by treating the central banks as a dying breed put off the inevitable. The political choices made in 2008 have allowed central banks to hallow out the global economy and financial markets until someone figures out how to replace the system.  This is what made the election of 2020 such a big deal in Washington DC.  This should explain to you why 100% of Wall Street was supporting a Biden tocket and not a Trump victory.  Biden has promised them a Treasury secretary that allow them to continue to print money until they can solve the problem they created.  Do you trust them to get it right for you or your family?

The government knows a financial reset is coming (cite one) and both sides of the aisle want a say in what the new system will look like.  Trump’s idea was outside of the mainstream of both parties.  He offered a different view point that mimic what Henry Wallace offered the American public as FDR longtime VP.  In 1944 the DNC decided they could not afford Wallace’s view point to take over the democratic party.  That is why he was removed politically in 1944 in 9 minutes while party bosses gave the nod for Vice President to worthless politician named Henry Truman.  They knew FDR was dying of polio and wanted to make sure they had a yes man in charge to control the terms of the end of WW2.  This is where Bretton Woods came from.  My recent Farm members have been taught how he came to power during their visits with old videos I have found to explain how he came to power.  Truman was the banker’s choice of Wall Street just as Biden is today.  Like FDR, Biden brain health is not good.  This is why a progessive leftist was installed as his VP.  She will push hard for huge wealth distribution and the banks won’t get blamed but Kamala will.  Biden was selected because he could be controlled by the real power brokers in the US.  The industrial military complex.  The same game plan that was in operation with FDR and Wallace is going on today in my opinion with regards to the recent election.

For starters, in the older macro economic models created by every president of the Federal Reserve since the Nixon administration, the US economy can ONLY grow with constant monetary support.  This is why Nixon got rid of the gold standard in 1971 when it no longer suited his purposes of reelection.

TIMING MATTERS IN BIOLOGY AND IN POLITICS

The global central bank crisis started at the turn of the year from 2018 to 2019.  It was clear to any economic doctor (bank Regulator) that the patient was terminal when one looked at their balance sheets.

When I looked at these charts in 2019, I understood what C19, the “Chinese flu” real purpose might be. It is all a dog and pony show to hide the real truth.  Our government has been stealing value from us for decades and has no out card to get out of the mess without us finding out about it.  Then I realized immediately that with a devaluation, any asset with value had to be removed into something that had value the central bank could not  touch.  The pandemic current events of 2019 was going decrease the slope of the line FOR TIMING of the “great reset” so that it would happen faster than anyone thought.  It was going to give bankers political cover to blow up a dying economic system using a made up pandemic.

Right now there’s no institution on earth that I despise more than the World Economic Forum.  I don’t trust a word they say! If the Illuminati really exists, they are it.  Opt out. Unbank yourself and buy BTC before it gets to its network effects.  The Chinese flu was designed to bring politcal and economic change faster than the American public can stomach it without stimulating a revolutionary war.  They want to hide their banking blunders in the facade of a global plandemic built by a a faulty PCR test to create a casedemic.

How do you appease the public when you are robbing them blind since 1971?  With cheap money.  The Fed has provided massive stimulative monetary policies since 2008 to avoid civil unrest.  This was done by the quantitative easing algorithms the Fed put in place since the global banking crisis of 2008.  Just as a dying trauma patient needs a constant source of blood while it bleeds on the operating table, the US economy has an incessant need to chronic currency stimulation to remain alive.  This operation has been going on globally since 2008 way below your ability to perceive it.  That was by design so we did not take up arms and remove the government ourselves. The latter led to ballooning balance sheets among major central banks as the picture above shows.  This is not my opinion.  This is what the data the banks have shown us.  The problem is few people a financial literate to know what is really going on, so this gave them the chance to fool us with a planned event.  This also explains why they want our guns so badly.  They hope you have no tools to decipher what is really going on.  This is why the political events around C19 make no scientific sense to anyone who can think.

This technique is working for them.  No one seems to see their game plan yet.  But they are no longer hiding it as you can see here.  You need to see it clearly now.  The coronavirus pandemic is fuel to the fire that will lead to much more rapid change economically.  A Biden presidency makes the adoption of BTC as a new option much more rapidly than any of the central bankers anticipates.  Moreover, when the public sees generational value destroyed in weeks to months civil unrest will dominate.  A revolutionary war between us citizens and its government is a distinct possibility in the next 5 years.  That is why COVID was created to block people from the real truth.

The economy is imploding and the patient is now actively dying in front of us.  This pandemic is a huge signal for the Black Swan to pay attention too.  It has turned many of our coming economic events into  obvious forecastable significant events against the public. Now, it’s only the question of where to look to go to understand what the new world order is all about.  It is about protecting your tribe for the economic tsunami headed our way.  To see how much value has already been taken from us examine the next slide for some simple math that compares the Dow Jones Index from 1997 and 2020.  You’ll notice it appears many people have made money with this Index………..but is it all an illusion?  The illusion was done because few people understand how to calculate value over time using the proper comparisons.  Let us go back to the gold standard that Nixon took away from us in 1971 as our benchmark.

Wall Street and the public think we have had an epic run of equity profits, but when you break it down you see that we’ve lost almost 40% of our value because our currency has been devalued.

If you do not like this example how about we use your house as an example and not gold.

Housing prices have collapsed by nearly 98% as the graph below shows.  The average price of a US single-family home fell from 1407 BTC in 2015 to 36 BTC today. Current market conditions point to an additional 10 times drop in price.

SAT analogy time:  If “Bitcoin is too volatile.”  then  “Fire is too hot.”  The Wisdom: Learn to use new technology like BTC real quick folks.

Now you can see that the price of your house matters little when you are buying and selling homes with money that is not worth what the government said it was.  Still feel good about Washington DC?

The central bank-run economic governance model has reached the end of its lifespan my friends. We desperately need a more open and free economy and less intervention and continuous “rescues”. This path will not be easy, but the current end-point, global economic dystopia shrouded in a pandemic veil, courtesy of global central banks, is much worse.

First we humans put our communications, advertisements, inquiries, opinions, resumes, relationships, photos, music, and movies on the network. Now we are going to put our money on the network. It sounds bizarre until you understand the reason why it must happen.  That is the story of this blog.  If you missed Microsoft, Apple, Amazon, Google and Facebook, you might want to catch Bitcoin.  I believe its market cap will be higher than all of them combined shortly.

More than anything, we need true political leadership—the statesmanship, courage, and wisdom to see through the scare-mongering and distorted economic information.  We need a politician like henry Wallace who will stand up for the common man and do what is right and not what is easy.  We must confront dominant elitist economic shibboleths relentlessly to move past what is first and foremost an intellectual dead-end.  Sadly, I don’t see that politician on the horizon who can do this,  so you need a life raft until that person emerges.  That life raft is BTC.  It is now your job to inflate your raft by buying the raft yourself.  The money you put into BTC will be the air in that life raft.  The more you add the better your ride into this uncertain future will be so you can create an optimal environment for your biologic problems.  Read the paper below to understand why you action at this moment is critical to your future success

 

Many people thought the radio wouldn’t be important. Many people thought the TV wouldn’t be important. Many people thought the internet wouldn’t be important recently.

All were wrong, as we all found out.

Many people think Bitcoin won’t be important.  Do not be like them.  Use your critical thinking skills to win at life.  It is and always be about the survival of the wisest from here on out.  Drop me a comment below.  I am interested to hear your thoughts about this topic.

CITES:

https://news.bitcoin.com/control-the-pandemic-fed-chair-jerome-powell-predicts-the-entry-of-a-different-economy/

https://www.theinvestorspodcast.com/episodes/bf-001-bitcoin-common-misconceptions-w-robert-breedlove/

Sunlight is a gift that brings immunity to many pathogens. It just so happens the one everyone is interested in now, C-19 is one of those pathogens who has a strict seasonal variability.

A recent study has shown that Intrinsic Photosensitivity Enhances Motility of T Lymphocytes to improve motility to improve immune protection from pathogens.

Until recently, photoreception in mammals was believed to be restricted to the eye. Since 2017 we now know it is also a property of the skin.

The largest amount of T cells are found in the skin followed by the gut lining.

Normal skin contains a high density of T lymphocytes performing immune surveillance, and the total number of T cells resident in skin is estimated to be double of that in circulation

In this study it is shown that T cells possess intrinsic sensitivity to blue and UV light. Blue light links to T cell hypoxia and UV light decreases hypoxia by increasing oxygen to these cells to create a large free radical pulse to destroy pathogens.

1. Blue light increases [Ca^2+] in T cells which diminishes your immunity = increased C19 risk

Blue-light irradiation of Jurkat T cells triggers an increase in intracellular [Ca^2+] as measured by Fluo4 fluorescence which was followed by extension of lamellipodia

2. Irradiance and spectral dependence of T-cell photosignaling

Data shows that the light response depends on the total number of photons rather than irradiance flux or time and this observation supports the existence of a photon-counting mechanism.

3. Light generates Ca^2+ signals via a Src kinase/PLC-γ1 pathway

Blue-light dose-dependently stimulated phosphorylation of Lck, the dominant Src kinase in Jurkat cells.

4. Light generates H2O2 in T cells to fight viruses*

Flavins are readily photoreduced leading to the generation of ROS including H2O2. Accordingly, they confirmed that blue light irradiation of flavin-containing solutions, at similar doses (600 mJ cm^−2) used on T cells, produced H2O2 in vitro.

To directly and selectively monitor H2O2 levels they transfected Jurkat cells with the genetically-encoded H2O2 reporter, HyPerRed29. The researchers found that a low dose of blue light (300 mJ cm−2, 30 mW) was sufficient to trigger H2O2 production in Jurkat cells.

5. Therefore, we can now say definitively that the light in your environment can enhances T-cell motility* if it is solar based. We can also say that is decreases T cell function if the light you live under is man made.

The researchers observed that blue-light irradiation altered the morphology of T cells, inducing the extension of lamellipodia. Since motile lamellipodia are associated with cell migration they measured effects of light on T-cell motility by tracking the movement of activated CD8+ T cells across a fibronectin-coated surface. Low levels of blue light (120 mJ cm^−2) increased random T-cell motility and the peak surface area (reflecting spreading lamellipodia), an effect that persisted following irradiation. Thus, T cells exhibit photokinetic behavior.

Next, they measured effects of light on chemotaxis. Figure 5d shows that irradiation with white light (1–5 J cm^−2) enhanced migration of Jurkat T cells towards the T-cell chemokine, stromal-derived factor. Light increased chemotaxis in a dose-dependent manner with a peak 100% increase observed at irradiances greater than 2 J cm^−2.

REMEMBER: There is not a politician on this planet that is going to save you. Wearing a mask for a nanoscopic virus is pseudoscientific as the recent Danish study showed. The LA Times seems to have a reading comprehension problem.

This shows you the main stream media is another step closer to George Orwell’s Ministry of Truth (“1984”):

The LA Times tweet above was referring to the Danish mask RCT, ???????????????????? ???????????????????????? ???????????????? ???????????????????? ???????????? ???????????? ????????????????????????????????????, blatantly lies and reports the exact opposite conclusion!

A new low is made every day to get control of your behavior and life.

Lock downs are also pseudoscientific. Politicians could care less about biology; their only interest is in how much control you’re willing to give them by decree.

Don’t be fooled — you are responsible for yourself. This is a Black Swan mitochondriac axiom. Politicians need to live this axiom: Integrity is not a 90% thing, not a 95% thing; either you have it or you don’t.

#medicine #sunlight #aheadofthecurve #electromagnetic

CITES:

https://lnkd.in/g-vVDyB

Wow. BlackRock CIO of Fixed Income Rick Rieder talking about Bitcoin replacing gold on CNBC this morning. pic.twitter.com/9KZR0muJVp

— Pomp 🌪 (@APompliano) November 20, 2020

Black Swans need to pay attention to this topic. Many of you may not understand how health and wealth are linked but in the world being built right now by politicians that linkage in a few years will be undeniable and dangerous for those who fail to heed the warnings I am sharing now. This will be the antidote to the medical algorithms you’ll face from the aftermath of this pandemic. The relationship between health and wealth is called “gradient”: the health improves when the income grows, and the poor has worse health than the rich, what means the higher the gradient the better the health.

Now I want you to look at what a leading UK politician recently said to the news below.

^^^^The thinker who is linear will find this argument compelling.  But the thinker who plays 4D chess when everyone else is playing checkers will know the data behind these ideas show us something else.

This blog series is about the relationship between health and wealth. The goal is to show that they are connected to each other, and that improving health can lead to improve of wealth.
The first part discusses the effect of health on wealth and vice versa. It shows that better wealth is connected to better health and health increase lead to the wealth increase.  This is opposite to what the politician says above.

Then there is a theoretical model by Grossman (1972) and which was modified by Jacobson (2000). The model shows that the health is seen as “a stock” and that individual can invest into the health during the lifetime. The model shows also the change, when there is a family without children (partners can invest into each other’s health) and the family with a child (parents invest into child’s health).

The wage and education effect is shown and developed by Grossman (1972). The increase in wage leads to increase in health, individual has more money to visit the doctors who can give the correct answers to problems and not the ones designed in a government algorithm which goal is to limit government costs.  The algorithm is not optimized to your health. This is why it is given away in free healthcare systems.

Why should you come to this site or become my member longer term?  I will improve your health and wealth in ways few of you understand now.  Any increase in education should also leads to increase in health, but in this case individual gets more information on healthy lifestyle and follows it.

Many literature reviews show how education, social status, early childhood, family and nutrition affect the health span. The better educated (mitochondriacs) have better health and higher income over time. An additional year of education increases the life. I am going to tell that only corresponds to those who get the RIGHT education that marries to ideas that follow nature’s laws.

Lower socioeconomic status increases the probability of consuming unhealthy goods and being less educated. Medical algorithms are built to educate the masses for the benefit of govenrment, not for the public’s good.  This defines what a medical tyrrany is.

The subjective social status affects the childhood, the mental health and the income. Family plays a crucial role: the mother’s health, parents education, family’s socioeconomic status effect the health of a child and the future income. The low birth weight, mental health problems in childhood and bad nutrition lead to problems in health in the future and lower income.

When the connection between health and wealth, and factors affecting the health become known, it is easier to implement policies to increase the total health and wealth. The healthy individual is more productive and it eventually leads to economic growth.  Right now the world is imploding economically because of virtual reality pandemic built by politicians to bail out a failing monetary policy that is happening globally.

As I mentioned above the relationship between health and wealth is called “gradient”: the health improves when the income grows, and the poor has worse health than the rich, what means the higher the gradient the better the health. Poor health decreases the time available for working and decreases the earnings, at the same time it increases medical expenses, all of these lead to even poorer life than before.

I believe that increasing the health is one way to increase the wealth.  Here is an example to support my contentions above.

Candeias (2016) studied the effect of diabetes on the economic growth. The number of people having diabetes is rising. In 2010 around 11.6% of the total health expenditures in the world were spent on diabetes. Candeias writes: “Diabetes, and other preventable non-communicable diseases, can lead to increased absenteeism and reduced productivity while at work, inability to work as a result of disease-related disability, and lost productive capacity due to early mortality and exclusion from the workplace to take care of sick family members.”

Candeias (2016) concludes that preventing diabetes will help to prevent other diseases, like cardiovascular diseases and cancer, and the households can spend more money on other goods and services.

The relation between health and wealth

James P. Smith (1999) made calculations using data from Panel Study of Income Dynamics (PSID). His researches are based on the data from the United States of America. He made a table (Table 1) for different age groups and 3 different years (1984, 1989, 1994), where he showed the correlation between self-reported general health status and income (in 1996 dollars). He noticed that those in excellent health in 1984 have 74 percent more wealth than respondents in fair or poor health do. This difference in income is also related to schooling, “median incomes of 1984 college graduates were $77 000 compared to $ 28 000 among high school dropouts – virtually the same as the income gradient from excellent to poor health.”(Smith, 1999).

According to Smith, changes in health lead to changes in income. Among those in the age group 35- 44, who reported excellent health in 10 years (from 1984 to 1994) the medium income almost increased by $100 000, at the same time the income of those who reported fair or poor health increased only by less than $10 000. So, if the person’s self-estimated health increased from 1984, his or her income also increased.

The other factors which influence health are risk behaviors – like smoking, eating unhealthy food, drinking alcohol etc. These risk behaviors are more common in lower socioeconomic groups. For example, Marmout (1999) has found that the percentage of those with lower incomes or less education smoking is higher than of those who are well educated or earn more. In 1995, 40 percent of men who had not studied in a high school smoked, while only 14 percent of male college graduates smoked. Similar health patterns exist for other risk behaviors.

It is also important to mention that periods of poor health in the middle age has a negative impact on retirement. If the earnings are reduced in the middle age, it will lead to reducing of the pension and social benefits later on. Smith (1999): “Since health status is positively correlated even across quite distant ages, a correlation of retirement income and current health may flow from past health to current retirement income”.

As was mentioned before, health has an important influence on wealth, if the person experience poor health it may reduce the savings and the current income, at the same time it may increase out- of pocket savings. In this sense, the Black Swan should look at “health is a stock“, which has potential effects on future income, consumption and medical expenses.

Smith (1999) made a table using the data from Health and Retirement Survey (HRS) and from the Asset and Health Dynamics of the Oldest Old Survey (AHEAD). The table consists of two households, ages 51-61 and ages 70+, and distributions of out-of-pocket medical expenses separately for those who experienced severe, mild or no new chronic diseases. Smith explained that severe conditions were defined as cancer, heart condition, stroke, and disease of the lung. All other onsets defined as mild.

The results show that the expenses with severe new chronic diseases for average 70+ aged individual are almost double compare to the one with no new chronic disease. And in the age group 51-61 the difference in expenses is more than double. And in both age groups 2 percent with new chronic diseases spent more than $30 000.

Smith argues that these results can be helpful to understand savings behavior that “some current wealth may have been accumulated to deal with today’s health problems”.

The problems in health reduce also the labor supply. In case of family, the spouse can work more and invest into the partner; this can be seen in section 3. But anyway the current health problems may reduce the household income in the retirement period.

Another way when health affects savings is when the individuals want to consume more when they are healthy than during the period when they are sick. So it can be that savings rise if the individual expect himself to get sick.

Smith (1999) also made an empirical model which estimates effects of new chronic health problems on household wealth accumulation and the pathways through which savings effects take place. The data he used was from panel surveys of HRS and AHEAD, he used the ordinary least square regression models and the results are in table 3. The table has 3 columns (dependent variables), which shows “between-wave” (there were several surveys conducted in three different years, and Smith calls these surveys as “waves”) changes in total household wealth, OOP=out-of-pocket medical expenses and total medical expenses. The results are mean estimates.

The table 3 shows that even with the mild onset in ages 51-61 with total medical expenditures $2 555, and the out-of-pocket expenditures are $635, the household wealth is lowered by $3 620. But with the severe onset diseases, when the out-of-pocket medical expenditures are not yet that high, the wealth is lowered by $16 846. The change in wealth is even more dramatic for the household with above median income, the household wealth is lowered by $25 371. There are alsoresults showing that health insurance doesn’t affect much on the incomes lowering, the difference is $175.

Because there was not enough data available for AHEAD, there is no information for mild and severe onset separated. The table 3 shows that any disease lows the income by $10 481. There is no information on total medical expenditure in AHEAD, that’s why Smith put NA in the column. In case of households ages 70+ the income is also has a dramatic lowering for the ones with above median income – $17 040.

Because table 3 doesn’t show the reasons behind the income lowering, except the health conditions, Smith made calculations using “empirical models of the alternative pathways though which wealth accumulation can change – out-of-pocket and total medical expenses, changes in labor supply and household income, changes in bequest intentions, and changes in mortality expectations. Three waves of HRS and two waves of AHEAD were used with separate models estimated for changes observed between each survey wave”. Table 4 shows the results.

From the table 4 can be seen that the out-of-pocket medical expenses are over $1 600, what is low enough compare to the total medical expenses. So the out-of-pocket expenses are not the main reason for the low income. When the new health problem is severe – the change in weekly hours is about 4 hours per week and a 15 percent point decline in the probability of staying at work. And there is no evidence if the person returns to normal weekly hours. The change in own earnings is lowered by around $2 600. The table 4 also shows that with new health “shocks” the person also changes the expectation in probability of living to 75.

Where does BTC, the new stock for the Black Swan fit in this story?

At the same time Smith agreed that these results create a puzzle for us to solve, the out-of-pocket medical expenditures are not that high compare to the total medical expenditures, and the change in income own earnings is not that big, but the total change in wealth, shown in table 3, can be dramatic.   This is where the idea of BTC comes in to build your future health.  

Smith explained that it can be caused by “measurement issues that understate medical costs or household income changes, or that overstate changes in household wealth. Out-of-pocket medical costs may well understate the full financial costs of an illness.   Becoming chronically ill is devastating to wealth, more than any other factor I have researched including taxes.  There are expenditures associated with an illness of a family member – transportation, reconfiguration of home care environments, and so on – which people may not think of as medical costs and are often not reimbursed.

“Although household wealth is notoriously difficult to measure, it is not apparent why any errors should be systematically related to health events unless estimates of wealth shift from optimistic to pessimistic with the onset of an illness.”

At the same time with the reduction of income, there is possibility for rising consumption of household; Lillard and Weiss (1993) found out that the marginal utility of consumption increases in periods of poor health. Also people may “invest” in their siblings or consume at a very high rate.  So if you begin to spend a lot this will draw down your savings.  Relocation to optimal environments is a key health span cost that Black Swans rarely plan for.

The case for membership with me is about education and thinking.

The day this picture was lifted out of the paper BTC was at 14K dollars.  Today, it is close to 19K and today is only two weeks later.  I told all my members at my July 4th, 2020 event the single greatest thing I could do to help their health right now was to make the case for them to buy any amount of BTC before the election closed in November.  On July 4, BTC was below 10K per BTC.  Why did I say it?  What did I see coming that too few saw coming?

I believe Black Swan mitochondriac education will also help to train people for decision making and problem-solving, to get information about healthy lifestyle and possible treatments. This will help them avoid medical algorithms designed to harm them.  Under a Biden regime medical algorithms will take center stage in American healthcare to limit costs by taking care out of healthcare.

Moreover, we know education may have biological effects on the brain.

The other important factor which affects health in the future is the childhood. What will our kids look like in a technocracy going forward? Blue light has a massive effect on embryonic health and this implies the cost of having children is going to skyrocket.

Barker (1997) wrote that the health of an embryo has an effect of the future health problems. For example, the lack of natural light and lowered oxygen tensions for an embryo leads to the low birth weights and to the disproportionate growth in different parts of the body and these can lead to the coronary heart diseases 50 or 60 years later.

Another effect on health during lifetime is stress related to the job and family. In a technocratic society that is limiting our freedoms to gather, celebrate, and live, this has driven the cortisol melatonin axis in health to dangerous levels. This is why suicide and diseases have climbed tremendously this year. More people are dying now of non covid diseases because of policy changes instituted by govenments. None of the policies are sceintfic. When you lose control of freedom you better have a stable of value to support you in a storm. This is why this series is being written. The time is now……..not later to make changes to your life. You may never get this opportunity again.

When the person is under the stress or threat, the level of adrenaline can increase which allows body to perform at higher levels. The trade off is it destroys dopamine and melatonin and sets up the stage for chronic health demise.  Increased adrenaline provides simultaneous challenges for blood pressure, heart rate and the immune system. In the short-run this changes are not dangerous, but when the stress occurs too often, the results can lead to disease, like high blood pressure, diabetes or poor sleep.

Income inequality is also one of the key factors which affect health. A common idea is that the social inequality raises levels of psycho-social stress which negatively affects adrenaline and immunological processes. In industrial countries the material level matters less than the fact being at the bottom in the social ranking. (Smith, 1999).  Many of you may not understand these linkages but I want you all to know that this doctor does understand it and I want you all to know that talking to your doctor about wealth is a health discussion.

THE TAKE HOME FOR THE MITOCHONDRIAC:  Three most important comments made in interview above:

Does he own BTC? No. This means his bias is low.

Is it worth the price today? He says, I don’t know.   That is an honest answer.

Is it a durable asset class, that is trackable and has the potential to replace gold? Yes.  That tells us he sees the thermodynamic value of BTC to generate wealth to increase our health span.

Black Rock controls 7 Trillion dollars for clients.   This tells us, that the Cheif information officer at a behemoth sees the case this asset.

The present reality is now flipping before our eyes my swans – everything will eventually settle in Bitcoin.  Data is the new dollar in a post COVID world.   Oil -> Bitcoin-> <Bitcoin -> Fiat -> Next commodity Gold -> Bitcoin-> <Bitcoin -> Fiat -> Next commodity.  That is the new flow chart.

My parting shot comes from current Kruse Longevity Center member Johan Lindstrom:  He made this statement yesterday to me at the pool in Tulum yesterday after he arrived from Norway.   “Jack, my family initially thought it was nuts for me to pay out of pocket to see a physician in the USA when I am in pretty good shape, but the results of my visit have not only helped my health, you have helped me create a new wealth platform that has paid for my membership many times over in less than a year.  That ability to think outside the box is extremely valuable to me and my family and I appreciate it.”

Health is a function of how well we are able to think.

Johan, a father of three young children now sees how health and wealth are linked.  This makes me happy that a citizen of an EU country sees the forrest through the trees.

It is time for some of you to begin to think in non-linear fashion as well.  Are you ready?  Join my tribe.  kruseatdestin.com

CITES: 

Grossman M (1972) On the Concept of Health Capital and the Demand for Health. Journal of Political Economy, 80: 223-255

Grossman M (2015) The Relationship between Health and Schooling: What’s new? Nordic Journal of Health Economics, 3(1): 7-17

Jacobson L (2000) The Family as Producer of Health – an Extended Grossman Model. Journal of Health Economics 19: 611-637

Smith JP, Healthy Bodies and Thick Wallets: The Dual Relation between Health and Economic Status, 1999

Candeias V (2016) 5 Reasons why Tackling Diabetes will Boost Economic Growth. https://www.weforum.org/agenda/2016/04/5-reasons-why-tackling-diabetes-boosts-economic- growth/

Strulik H (2018) The Return to Education in Terms of Wealth and Health. The Journal of the Economics of Ageing, 12: 1-14

https://cryptoticker.io/en/bitcoin-over-gold-investment-bank/

LUKE’S PRESCRIPTION: Where observation and epiphany collided at this years member event.

IgA responds to native magnetic fields and this links it to seasonal viral illness and to gut abnormalites. How does this occur?

There is a clinical correlation between an allergic patient’s ability to resist the development of symptoms that would have resulted from an allergenic challenge, the magnitude of geomagnetism at a geographic site, and (3) the amount of solar energy falling on that site. It is suggested that the digestive membrane has an electronic gatekeeper that “decides” electronically which molecules to allow or not allow to pass on to the absorptive surface. The unique bipolar structure of secretory immunoglobulin A (IgA), having a central secretory piece and the resultant unique electronic function of this polarized molecule, allows it to function as an electronic transistor, producing an electronic gatekeeper in the form of an electronic sieve.

High-gradient magnetic fields (HGMFs) have steadily gained the increased attention of researchers from different disciplines, such as cell biology, cell therapy, targeted stem cell delivery and nanomedicine because magnetic fields change cell structure and size. Recent theoretical framework has provided a fundamental understanding of the effects of HGMFs on intracellular processes. It appears altered magnetic fields have huge impacts on IgA creation and destruction. This science highlighs new directions for the study of living cell machinery: changing the probability of ion-channel on/off switching events by membrane magneto-mechanical stress, suppression of cell growth by magnetic pressure, magnetically induced cell division and cell reprograming, and forced migration of membrane receptor proteins. By deriving a generalized form for the Nernst equation, we find that a relatively small magnetic field (approximately 1 T) with a large gradient (up to 1 GT/m) can significantly change the membrane potential of human cell and thus have a significant impact on not only the properties and biological functionality of cells but also cell fate.

^^^^^  This is the most detailed model of a human cell to date, obtained using x-rays, nuclear magnetic resonance, and cryoelectron microscopy data sets.  Source and Credit: Transformation of the Cellular Landscape through a Eukaryotic Cell, by Evan Ingersoll Ingersoll Gael McGill ~ Digizyme’s Custom Maya Molecular Software—-Biología Al Instante

Current antibody tests for COVID-19 test only IgM and IgG, and assume that IgM represents a recent infection, while IgG will represent a recent or distant infection. IgM comes first, followed by IgG. IgM disappears rather rapidly, while IgG stays elevated for a very long time. Therefore, IgM suggests recent infection whether IgG is present or not, while IgG alone suggests an infection in the more distant past. In the first week, there are nearly twice as many people who are positive for IgA to the spike protein than those who are positive for either of the other antibodies. IgA continues to be most prevalent in the second week, and it is almost as prevalent as IgG in the third and fourth weeks. IgM is never the most prevalent, and it drops off in the fifth week just like IgA. Only IgG remains prevalent in the fifth week. IgA antibodies were five times more effective than IgG antibodies at neutralizing SARS-CoV-2, the coronavirus that causes COVID-19.

The patients whose IgA had the greatest ability to neutralize the virus were the ones who had the highest levels of IgA against the spike protein.  this means those who can harness the magnetic flux of the sun best have the lowest risk of C19.  It also means these are the people who won’t have gut issues from other causes.

Secretory immunoglobulin A is the dominant antibody isotype in mucosal secretions and plays an essential role in defense against pathogenic microorganisms bacterial and viral. However, even in the absence of infection, the body produces approximately four grams of IgA daily, more than all other antibody isotypes combined. Much of this IgA is secreted into the intestinal lumen, where it binds to and ‘coats’ specific members of the gut microbiota—the trillions of bacteria/viruses that constitutively colonize the human intestinal tract.

The gastrointestinal mechanism responsible for sorting molecules that were to be absorbed or rejected appeared to be related to the subject of electronics. The sorting process could be explained by the existence of an electronic sieve created via a massing of electronically enabled secretory immunoglobulin A (IgA) molecules, each acting as an electronic transistor. This electronic transistor function of secretory IgA can be achieved because of its bipolar structure and unique mid-secretory piece.

Secretory IgA plays a crucial role in shaping the composition and function of the gut microbiota in animals. It appears IgA responds to the varying magnetic fields on Earth between day and night.

Selective IgA deficiency (sIgAd), defined as a serum IgA concentration of less than 7 mg/dl with normal levels of serum IgG and IgM in subjects greater than four years of age, is the most common primary immunodeficiency in humans. Its incidence varies by geographical region, ranging from 1:700 in individuals of European descent to 1:18,500 in Japan. Location on Earth is linked to magnetic field strength variation. While IgA deficiency is often described as “asymptomatic,” sIgAd subjects exhibit increased incidences of infectious, allergic, and autoimmune disorders including inflammatory bowel disease. Secretory IgM can partially compensate for the lack of IgA in sIgAd subjects but not completely. Latitude and location seem to be the key to understanding the seasonality or the risk of electromagnetic pollution in many diseases.

UNCLE JACK’S TAKE HOME FOR LUKE: It appeared that the higher the geomagnetic properties of the area you live in, the more resistant the patient was to known allergens.  It appears if you live in a state with a lot of gas or oil deposits where drilling or fracking occur the more likely you will be to have gut issues. If you want an antidote move to the rim of the crater in PDC and Tulum and see how your symptoms respond. You might become able to turn on your electronic IgA transitor properly.

The gut mitohacker should investigation using the USGS color aeromagnetic anomaly map of the contiguous United States should be a top priority.

You should expect a sunset effect and seashore effect because of how magnetic flux varies at these times daily. You will crash at sunset and you will do better at the seashore with respet to all your allergens.

At the seashore or at a water fall you get a huge “Lenard effect”. This is when net negative ions are added to the air. This makes you more sensitive to magnetic flux and should improve your symptoms. An increase in ambient atmospheric negative air ions clinically appears to have a salubrious effect on a patient’s ability to successfully deal with a challenge from a known food allergen or from an altered microbiome.

Those with gut issues or weakened immune system should struggle with Faraday cage effects. If you use devices or a field-free room (Faraday cage) you might get worse. Within minutes after entering these rooms I have noticed over the years individuals experienced weakness and severe fatigue as a result. This told me IgA was their problem.

It appears to me as if the energy of the sun is capable to changing the magnetic suceptibilty of the gut and immune system. Observation of several of the Kruse Longevity cases over the last two years have given me this insight.

The final piece of the puzzle came for this October 2020 when I observed Luke over 4 days. I saw an amazing effect of a hurricane in the Gulf on Destin Fla Gulf and then observed changes at Morrison Creek and began to put things together. The eureka moment happened during a small speach from Luke in front of many where he came apart.  Sometimes we have to come apart to fall back together.

I realized that the sun’s magnetic flux was being absorbed in a kind of electronic “alimentation” that provided free energy to reverse entropy and allow for the accumulation of properly sized particles on one side of the digestive membrane, thus allowing secretory IgA to act like a kind of Maxwell’s demon.

Was this an evolutionary mechanism that animals developed to capture free solar energy just as plants developed photosynthesis as their mechanism for capturing free solar energy? I now suspect that secretory IgA is such a device that enabled this energy-capturing process to take place in the gut by acting as an electronic transistor to sculpt the microbiome and its immunologic response.  Could this a be a magnetic control gate for the brain?

Might gut IgA be the brain’s main protector.?

IgA cells that originate in the gut play a role appear to have neuroprotective properties against diseases associated with neuroinflammation, such as meningitis or viral infection.

The membranes surrounding our brains (dura) are in a never-ending battle against deadly infections, as germs constantly try to elude watchful immune cells and sneak past a special protective barrier called the meninges. In a study involving human autopsy tissue, researchers at the National Institutes of Health and Cambridge University have shown that some of these immune cells are trained to fight these infections by first spending time in the gut.

It appears gut-educated antibody-producing cells inhabit and defend regions that surround the central nervous system.   Without a proper IgA response the brain becomes attacked and mental and cognitive changes become more likely.

The central nervous system (CNS) is protected from pathogens both by a three-membrane barrier called the meninges and by immune cells within those membranes. The CNS is also walled off from the rest of the body by specialized blood vessels that are tightly sealed by the blood brain barrier. This is not the case, however, in the dura mater, the outermost layer of the meninges. Blood vessels in this compartment are not sealed, and large venous structures, referred to as the sinuses, carry slow moving blood back to the heart. The combination of slow blood flow and proximity to the brain requires strong immune protection to stop potential infections in their tracks.

The immune system has invested heavily in the dura mater. The venous sinuses within the dura act like drainage bins, and, consequently, are a place where pathogens can accumulate and potentially enter the brain. It makes sense that the immune system would set up camp in this vulnerable area to protect its Ferrari engine.

IgA cells had not been shown to reside in the dura mater under steady state conditions.  Now we know they do.

A recent study by the NIH (Cite two) discovered something surprising: there were many immune cells previously educated to make antibodies against specific microbes and viruses. These antibody-producing cells, called IgA cells, are typically found in other barriers such as the mucous membranes of the bronchial tree of the lungs and gut.

Pathogens present in the gut were important in educating meningeal IgA.

This new data provide more compelling evidence that the brain is protected by immune cells that are educated in the gut and lungs.

IgA is a magnetic transitor that needs to be present and active to repair the gut and brain.  Where you live matters deeply in this electronic dance with Nature.

 CITES

https://www.nature.com/articles/s41598-019-49923-2

“Gut-educated IgA plasma cells defend the meningeal venous sinuses” by Zachary Fitzpatrick, Gordon Frazer, Ashley Ferro, Simon Clare, Nicolas Bouladoux, John Ferdinand, Zewen Kelvin Tuong, Maria Luciana Negro-Demontel, Nitin Kumar, Ondrej Suchanek, Tamara Tajsic, Katherine Harcourt, Kirsten Scott, Rachel Bashford-Rogers, Adel Helmy, Daniel S. Reich, Yasmine Belkaid, Trevor D. Lawley, Dorian B. McGavern & Menna R. Clatworthy. Nature

Here is a brief history lesson time for those who do not understand how Bitcoin finance links to medical risk.

YOU SHOULD WATCH THE VIDEO ABOVE FIRST

PRESENT MOMENT:  WW2 uncovered a massive problem in financing using conventional banks in the post war period.  The baby boomers are driving massive use in healthcare because they are older and sicker.  1 million people per day become 65 years old in 2020.  Because of this, the USA is on track for a medical/retirement bankruptcy soon in the USA.

So anything that limits population size above the age of 60 will become excellent public policy because of what Nixon did in 1971.

Do you think this is hyperbole?

Do you want to continue to play checkers while some of us want to teach you to play 4D chess?

Our population is very ill  and OLD and the system is not able to handle their costs.  I see a bankruptcy of California and NY coming quite soon because of policy decisions.  Presidential decree and Congressional bailout are required to bail out a state.  Once this happens, money will be printed at will to pay the debt.   When did the US dollar become a FIAT currency?  1971 under Nixon.  This was done when Nixon announced the War on Cancer with Alton Ochsner.  The link for my members should now be obvious.  It was linked to the polio virus contamination with SV-40.  The government knew that there would be a coming chronic disease pandemics and had to do something to react to it.

President Nixon said to the Nation during his January 1971 State of the Union address: “I will also ask for an appropriation of an extra $100 million to launch an intensive campaign to find a cure for cancer, and I will ask later for whatever additional funds can effectively be used. The time has come in America when the same kind of concentrated effort that split the atom and took man to the moon should be turned toward conquering this dread disease. Let us make a total national commitment to achieve this goal.”

As part of this national effort, in October 1971, the Army’s Fort Detrick, Maryland, biological warfare facility was converted to a cancer research center, eventually becoming the Frederick Cancer Research and Development Center, an internationally recognized center for cancer and AIDS research.  That last part should perk your ears up.  AIDS is linked to the SIV for those who do not know.  Those of you who attended my July 4, 2019 event should really be perking up about now.  It was at this event that you heard me speak about the polio virus and the coupling to Bitcoin for the first time for my members.   I know it left many of you asking questions but this blog series will begin to close that gap.

On December 23, 1971, President Nixon followed through on his promise as he signed the National Cancer Act into law, declaring, “I hope in the years ahead we will look back on this action today as the most significant action taken during my Administration.”

The National Cancer Act (P.L. 92–218), “The War on Cancer,” gave the NCI unique autonomy at NIH with special budgetary authority. We see that unique behavior now born out in how Dr. Anthony Fauci has run free during the C19 pandemic.  Not even a president can keep a lid on his behavior.  You must ask yourself why this is the case.  I am asking you to look back to 1971 to understand what is really going on today.

The Cancer Chemotherapy National Service Center (CCNSC) increased its efforts to acquire new compounds for testing with the awarding of an acquisition and inventory contract responsible for the collection and documentation of test agents.

What else did they do at the same time?

Nixon created a shock wave for the economy.  The Nixon shock was a series of economic measures undertaken by United States President Richard Nixon in 1971, in response to increasing inflation, the most significant of which were wage and price freezes, surcharges on imports, and the unilateral cancellation of the direct international convertibility of the United States dollar to gold.

While Nixon’s actions did not formally abolish the existing Bretton Woods system of international financial exchange, the suspension of one of its key components effectively rendered the Bretton Woods system inoperative. While Nixon publicly stated his intention to resume direct convertibility of the dollar after reforms to the Bretton Woods system had been implemented, all attempts at reform proved unsuccessful. By 1973, the Bretton Woods system was replaced de facto by the current regime based on freely floating fiat currencies.

Since President Nixon’s decision to decouple the US dollar from gold in 1971, a system of national fiat currencies has been used globally.   My Black Swan who get this coupling are now talking about it privately.  My Farm members get more of this wisdom and insight than any other.  This is why I spoke about it publically for the first time in July of 19.

What is FIAT money?

Fiat money can be:

Any money declared by a government to be legal tender.

State-issued money which is neither convertible by law to anything else, nor fixed in value in terms of any objective standard.

Intrinsically valueless money used as money because of government decree.

An intrinsically useless object that serves as a medium of exchange.  Before fiat money the US dollar was pegged to the gold standard.  When and how?  The Bretton Woods system of monetary management established the rules for commercial and financial relations among the United States, Canada, Western European countries, Australia, and Japan after the 1944 Bretton Woods Agreement. The Bretton Woods system was the first example of a fully negotiated monetary order intended to govern monetary relations among independent states. The chief features of the Bretton Woods system were an obligation for each country to adopt a monetary policy that maintained its external exchange rates within 1 percent by tying its currency to gold and the ability of the International Monetary Fund (IMF) to bridge temporary imbalances of payments. Also, there was a need to address the lack of cooperation among other countries and to prevent competitive devaluation of the currencies as well.

Preparing to rebuild the international economic system while World War II was still raging, 730 delegates from all 44 Allied nations gathered at the Mount Washington Hotel in Bretton Woods, New Hampshire, United States, for the United Nations Monetary and Financial Conference, also known as the Bretton Woods Conference. The delegates deliberated during 1–22 July 1944, and signed the Bretton Woods agreement on its final day. Setting up a system of rules, institutions, and procedures to regulate the international monetary system, these accords established the IMF and the International Bank for Reconstruction and Development (IBRD), which today is part of the World Bank Group. The United States, which controlled two thirds of the world’s gold, insisted that the Bretton Woods system rest on both gold and the US dollar. Soviet representatives attended the conference but later declined to ratify the final agreements, charging that the institutions they had created were “branches of Wall Street”.  These organizations became operational in 1945 after a sufficient number of countries had ratified the agreement.

On 15 August 1971, the United States unilaterally terminated convertibility of the US dollar to gold, effectively bringing the Bretton Woods system to an end and rendering the dollar a fiat currency.

FED policy since 1971 was tied to control of the money supply without any grounded basis.  This has given central banks extraordinary control over public policy.  The major driver of costs in the USA budget since 1971 has been healthcare driven by the aging baby boomer.

So what do I see in the future?

What do I see? The Fed under Biden will only have two moves left to control the money supply : Print more cash or go to negative bond rates. Do you know what both of those things mean to you medical future? How about your financial future?

What do I see as option three? Is there a lift raft awaiting the Black Swan who plays 4D chess when everyone else is focused on the wrong metrics? I believe there is. There is one algorithm that is designed to fight the algorithms that are being built in corporate medicine which are designed to harm you.

I see a new Bretton Woods happening in the USA and Bitcoin will be that standard. I think medical bankruptcy by medicare and the two state defaults as the replacement for Bretton Woods during WW2 to replace the fiat currency.

THOUGHTS?  Leave me a comment below if you are a patron.

If you are a member of KruseatDestin.com I have more for you.

If you want to begin packing your own parachute or life raft open a BlockFi account here: https://blockfi.com/?ref=34f06254

This is advice I have given my Farm members.  I will be discussing this during this months Q and A for members.  I plan on opening the Q and A for all groups this month because this topic is now critical given the election results in the USA.

This is why your circle of six matters. Consider this my friendly reminder to you, you better have the right sets of eyes looking out for you in the future.

Thyroid function is like a relay race, with hormones passing the baton from the hypothalamus in the brain to the pituitary gland beneath it, then to the thyroid gland, to the liver, and finally to cells throughout the body.

The hypothalamus delivers messages to the pituitary gland via the chemical messenger thyrotropin releasing hormone (TRH). Once TRH delivers its message, the pituitary gland releases thyroid stimulating hormone (TSH).

TSH goes straight to the thyroid gland where it triggers the production of a protein called thyroglobulin. The thyroglobulin joins up with four molecules of iodine to produce the thyroid hormone T4, or thyroxine.

About 94 percent of the hormone made in the thyroid gland is T4. The remaining 6 percent is triiodothyronine (T3), named for its three molecules of iodine.

These thyroid hormones hitch a ride through the bloodstream on thyroid-binding proteins, during which they are referred to as “bound.” When they are dropped off at the cells for active duty, they are called “free” hormones.

Although the thyroid gland secretes only a little T3, it is the most active form the body can use. T4 must be converted to T3 before the body can use it. Most of this conversion happens in the liver, but also take place in cells of the heart, muscle, gut, and nerves. These cells convert T4 to T3 with an enzyme called tetraidothyronine 5’ deiodinase, which removes one molecule of iodine.

In the end, only about 60 percent of T4 is converted into usable T3. Twenty percent becomes reverse T3 (rT3), an inactive form the body cannot use. Levels of rT3 can become too high in times of major trauma, surgery, or severe chronic illness. Another 20 percent of T4 can be converted to T3 by healthy gut bacteria in the digestive tract.

HOW DOES ALTERED T3 LEAD TO HYPOXIA IN ILLNESS?  

A key discovery during the coronavirus H1N1 pandemic of 2009, … victims’ lungs lacked T3, a thyroid hormone that would normally be detectable. T3 reduces inflammation and coaxes epithelial cells in the lungs to absorb fluids.   Since AM sunlight creates T3 the antiviral link of sunlight should now be apparent.  This can be seen in the pic below.

In non-thyroidal illness (NTI) plasma T3 is often decreased and plasma rT3 increased; plasma FT4 is still in the normal range depending on the severity of the disease. The changes in plasma T3 and rT3 are explained by a diminished conversion of T4 to T3 and of rT3 to 3,3-T2 by D1 in the liver.

Most plasma T3 is derived from the peripheral conversion of T4.  Viral diseases are known to act as mitochondrial toxins that can lower oxidative phosphorylation and subsequent ATP production.  This causes a relative pseudohypoxia to develop in the colony of mitochondria during a viral illness.

T3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3.  So a lack of T3 would exacerbate mitochondrial hypoxia in illness.  This is what we have seen clinically in C19 patients who became symptomatic.  Those with mitochondrial dysfunction before infection are at the highest risk of C19 sequela.  Their Vitamin D levels have acted as a predictive lab for clinicians because solar exposure is critical in making Vitamin D3 and T3 in humans photosynthetically.

Since H1N1 is an RNA virus that shows homology to SARS_CoV_2 #COVID19 it should be obvious why T3 drugs are now being tested clinically in high latitude cities in the USA where the sun has lost its power.

As solar power is lost what happens in mitochondria?  Oxygen tensions change, and this causes changes in energy production and alterations in ROS because dissolved oxygen in cells increase as ATP drops.

Recall that ATP production is increased by exposure to red light. Sunlight is 43% red light. Here is another link of sunlight to energy production.

Thyroid hormone is indispensable for the normal development and metabolism of most cells and tissues. Thyroid hormones are metabolized by different pathways: glucuronidation, sulfation, and deiodination, the latter being the most important. Three enzymes catalyzing deiodination have been identified, called type 1 (D1), type 2 (D2), and type 3 (D3) iodothyronine deiodinases. D1 and D2 have outer ring deiodinase activity, converting the prohormone T4 to its bioactive form T3 and degrading rT3 to 3,3’-T2. D3 has inner ring deiodinase activity and degrades T4 to rT3 and T3 to 3,3’-T2.

The most remarkable feature of all three iodothyronine deiodinase is that they are selenoproteins, i.e. they contain a selenocysteine (Sec) residue in the center of the amino acid sequence.  Seafood is loaded with selenoproteins.  It is also loaded with iodine.  This is why seafood is also another antihypoxic C19 strategy because it has a huge supply of selenium and iodine involved in T3 optimization to improve mitochondrial function.

D1 is largely expressed in the liver and kidney. Its main role is clearance of rT3 from the circulation and it also contributes to the production of plasma T3. D2 is importantly expressed in the central nervous system, pituitary, brown adipose tissue, and muscle and, generally, its expression reciprocally responds to changes in thyroid state. D2 serves to adapt cellular thyroid state to changing physiological needs. D3 is importantly expressed in fetal tissues and in adult brain tissue. In addition, D3 can be re-expressed under certain pathological conditions such as critical illness or in specific cancers and infectious diseases.

CITES:

https://www.startribune.com/hormone-boost-could-be-covid-19-key/572944532/

Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb;23(1):38-89.

Larsen PR, Zavacki AM. Role of the Iodothyronine Deiodinases in the Physiology and Pathophysiology of Thyroid Hormone Action. Eur Thyroid J. 2012.