Month: April 2020

Why is the WHO and the Chinese communist party facing the wrath of those who can think?

Both of them failed to utilize the precautionary principle with COVID-19.

What is this principle?

The precautionary principle places the burden of proof on the side that carries the uncontrolled risk…it is up to those who refuse the application of the treatment to demonstrate that it is more dangerous than the absence of treatment.

With that all said. He is the present reality:

Reported US coronavirus deaths:

Feb. 15: 0 deaths

Mar. 15: 65 deaths

Apr. 15: 30,844 deaths.

This rise defines what logrithmic growth is all about.

WHO ELSE HAS MASSIVE FAILED THE PEOPLE OF THE USA?  The entire media.  They have forgotten their role in the government.

The First Amendment to the U.S. Constitution protects the freedom of speech, religion and the press. It also protects the right to peaceful protest and to petition the government.

The MEDIA have forgotten that when they shirk their duties, and the first amendment fails the people, it makes it much more likely that the people will use their second amendment rights to take up arms against the tyranny of government.  We are now seeing aspects of tyranny.  Just look at what the governor of Michigan has done to the people who elected her.  They now want her recalled.  People do not realize how close America is to rising up.

The real reason Thomas Jefferson gave us the first  for freedom of speech in the first amendment of the constitution is this: Suppression of speech results in second and third-order problems (trust, authority, suspicion) that are far worse than first-order inconveniences from its freedom.  We all our standing on that precipice now.  All people of all ideologies.  This pandemic has forced everyone to take a road that they are not used to taking.  In non pandemic America, normally, precipices are the routine routes only that unroutine people take.   The reality of our situation, is that it’s only at the precipice that we evolve, only on the brink do we change.

Sadly our personal perceptions of the truth is only an approximation of what we believe based on the data we accept. What we accept then builds our cognitive biases.  The truth about the truth is that is never stops changing with new data.   This pandemic is causing many to see the fallacies in what they were taught.

If we really knew what to look for……most Americans are not good observers of their own government or their own ideology,  I have found.  This is why most people cannot see what was really going on around them in their lives before the pandemic.  None of them could put their finger on really why COVID-19 happened.  Most are blinded by their educational biases.   However, one thing should be clear to all now, this pandemic has taught everyone something is structurally wrong with our government.   This is true for the left or right leaning crowd.

WE”RE ADDICTED TO TECHNOLOGY AND ALIEN LIGHT AND IT LOWERS OUR DOPAMINE LEVEL.  THIS CAUSES US TO MISREAD THE TEA LEAVES.

We are all guilty of it.

We all need to remember the lessons from the past. Over-machined technocratic societies create environments that fail humans because they divorce us from our life force, Nature. We need to learn from this failure. The manufactured devices themselves condition the
users to employ each other the way they employ machines. They enslave us.
At its core the technocracy will always need a select few humans to keep the house of cards running. Technical people don’t make good slaves. Without their wholehearted cooperation, things will fall apart. That is how the slave trade the government allows to continue.  The FCC was given this power by CONGRESS and the military industrial complex now enforces it.  The NIH, CDC and CONGRESS try to keep us blind to it because they refuse to fund research that challenges the technocracy in this country.  Realize who did this to us.  Realize your role in allowing it to happen.   Realize your roll in how to stop it.

The customer can fire everybody in the company from the chairman on down, simply by spending his money somewhere else. We need to remind China’s CCP of this. Removing funding of the WHO is the first step in many that needs to be done.

By the time 5G is fully rolled out, the intellectual poverty of technocracy and the primacy of socialistic politics over it would be a well-established truth in need of no further defense.

Stopping your current ‘thought car’, and agreeing to look into the rear view mirror to see your real story clearly helps you re-navigate your life now, to change your future. That is truly what embracing nature does for black swans, in my opinion. You must embrace the suck. But embracing that first foul tasting step only does one thing. It stops you from living your life like your driving down a road just looking through the wind shield while your life- “time contracts” or you age faster and die sooner, like over 30,000 American have from this virus.

Medicine is fumbling the ball because it has no true epistemologic foundation to tie its biologic decisions too, like chemistry or physics has. The point is when we begin to use evolutionary biology to guide our decisions instead of our feelings and socially created beliefs, we get better permanently. We need to use evolutionary thinking to guide and master our thinking today. If you’re with me, I think you will get Optimal eventually. That is the modus operandi of my entire blog and it is the thesis of my life now.

Maybe I should stop calling my tribe “Black Swans” and instead refer to them as “Roosters”. People who exist among us to wake the rest of the sleeping awake with some truth.

o let us look at what we have all accepted due to COVID-19 and see if it marries to what our Constitution laid out for us 250 years ago.

Here are the official Coronavirus guidelines from our government:

1. Basically, you can’t leave the house for any reason, but if you have to, then you can.

2. Masks are useless, but maybe you have to wear one, it can save you, it is useless, but maybe it is mandatory as well.

3. Stores are closed, except those that are open.

4. You should not go to hospitals unless you have to go there. Same applies to doctors, you should only go there in case of emergency, provided you are not too sick.

5. This virus is deadly but still not too scary, except that sometimes it actually leads to a global disaster.

6. Gloves won’t help, but they can still help.

7. Everyone needs to stay HOME, but it’s important to GO OUT.

8. There is no shortage of groceries in the supermarket, but there are many things missing when you go there in the evening, but not in the morning. Sometimes.

9. The virus has no effect on children except those it affects.

10. Animals are not affected, but there is still a cat that tested positive in Belgium in February when no one had been tested, plus a few tigers here and there…

11. You will have many symptoms when you are sick, but you can also get sick without symptoms, have symptoms without being sick, or be contagious without having symptoms. Oh, my..

12. In order not to get sick, you have to eat well and exercise, but eat whatever you have on hand and it’s better not to go out, well, but no…

13. It’s better to get some fresh air, but you get looked at very wrong when you get some fresh air, and most importantly, you don’t go to parks or walk. But don’t sit down, except that you can do that now if you are old, but not for too long or if you are pregnant (but not too old).

14. You can’t go to retirement homes, but you have to take care of the elderly and bring food and medication.

15. If you are sick, you can’t go out, but you can go to the pharmacy.

16. You can get restaurant food delivered to the house, which may have been prepared by people who didn’t wear masks or gloves. But you have to have your groceries decontaminated outside for 3 hours. Pizza too?

17. Every disturbing article or disturbing interview starts with “I don’t want to trigger panic, but…”

18. You can’t see your older mother or grandmother, but you can take a taxi and meet an older taxi driver.

19. You can walk around with a friend but not with your family if they don’t live under the same roof.

20. You are safe if you maintain the appropriate social distance, but you can’t go out with friends or strangers at the safe social distance.

21. The virus remains active on different surfaces for two hours, no, four, no, six, no, we didn’t say hours, maybe days? But it takes a damp environment. Oh no, not necessarily.

22. The virus stays in the air – well no, or yes, maybe, especially in a closed room, in one hour a sick person can infect ten, so if it falls, all our children were already infected at school before it was closed. But remember, if you stay at the recommended social distance, however in certain circumstances you should maintain a greater distance, which, studies show, the virus can travel further, maybe.

23. We count the number of deaths but we don’t know how many people are infected as we have only tested so far those who were “almost dead” to find out if that’s what they will die of…

24. We have no treatment, except that there may be one that apparently is not dangerous unless you take too much (which is the case with all medications).

25. We should stay locked up until the virus disappears, but it will only disappear if we achieve collective immunity, so when it circulates… but we must no longer be locked up for that?

26. You wear a mask to protect others, not yourself.

Ask yourself, who are you really good for when you are not good enough for yourself?  Is this message our government is sending to us?  It is supposed to be for the people.  It was codified in “WE THE PEOPLE”.  Is this still true?

This is the reality of our modern tyranny.

SUMMARY

When your life stop’s pleasing you…..you’ve lost your randomness……change it with your new creations. Embrace the suck of the chaos we are all in now.  Chaos is what we’ve lost touch with when we gain comfort.

The reality we imprint upon our future is very often the idea of some lost, imagined past. This is unfortunate. The dream of past and future in our mind is akin to the contact of two chemical substances: if there is any reaction, both should be transformed before any reality is created.

Water and sunlight were the primordial matter on Earth to give life a start.  Light, water, and the electromagnetic force combined to give us the organizing elements on this planet.

How much more evidence do we need that ultra-processed man-made light are never good for us compared to sunlight?  The picture encompasses our entire problem.

All of us are maladaptive to the use of the light spectrum around us. The light bulbs are but one part of the technocracy, we’ve addicted ourselves too.

The irony here, our technocracy has blinded us to these facts. We have asked for more technology not less. Our govenment has given us exactly what we’ve asked it too. Are you satisfied on your precipice now? How is your current view?

The pandemic has caused me to pause and think about my past when I was awoken to Nature’s power. I was standing in Rome in the Sistine Chapel showing my son the center panel of Michelangelo’s masterpiece ceiling. What does let there be light really mean?

I realized that day I might want to know God’s thoughts about life.  What in the hell was he thinking in genesis?    I want to know God’s thoughts in a biologic way and I found the path to that way used an alphabet called evolution.

Evolution in my eyes is the following:

• It does not mean random
• It does not mean to improve
• It does not mean morphing during a lifetime
• It does not mean abiogenesis
• It does not mean the origins of the universe
• It does not mean social Darwinism
• It does not mean genetic determism
• It does not mean amoral
• It does not address theologic claims
• It does not mean atheism, communism, racism or any politcal ideology

Evolution means change over time brought about by environmental change in the Earth, pure and simple

How it happens is a natural truth based upon quantized science.  Quantum mechanism is the substance of nature and it is not based on cause and effect it is 100% based on probabilites of what can happen.  The thermodynamics of the environment is what causes reality to manifest.  What is happening to us now is due to our lack of insight of how our abuse of the electromagnetic spectrum is linked to this pandemic.

If you deny these things:  The universe, change over time, then, in my eyes,  you deny our current reality:

The theory of biological evolution attempts to explain the facts and connect the data that indicate that life on Earth is related through a common descent or process, and has been changing for close to 4 billion years. I am sure it will continue to evolve too.  We don’t have all the answers today, but we are getting better at finding some, and this post is foundational to evolution’s role, in life’s ascent at the ocean floor and eventually in Homo’s solution.

I told a friend parts of my new cognitive bias on this topic in a phone call in 2011, and told him when I was done with all this that I would leave no doubt in any one’s mind with what I found and why it altered my perception.  I told him about Factor X,  hoping he would see the was a bigger evolutionary story I was painting for people to see.

He explained that it might upset the ‘apple cart’ and I should expect some backlash.  I told him that people interested in ancestral living in Nature should be more interested in the truth of how our biology really works than what they believe.

Martin Luther King said it best, “Every time we witness an injustice of thought, and do not act, we train our character to become passive in its presence, and thereby eventually lose the ability to to defend ourselves and the one’s we love to create the life we need.”  I feel I need to write about this because our species survival is tied to these thoughts.  My hypoxia #8 webinar reminds me of MLK’s words daily.  This is the passion that drives me now.

My message, on my blog and book, was to be a true voice and not an echo chamber for the technocracy or the government that supports it.

It is time for you to change how you think about this pandemic.  It might be the thing that causes you to survive and thrive in the New World order that is being forced down our throat by the government we elected.

If you are struggling you might need to find your voice. Your inner voice is the amplifier of your heart and soul. We all have two kind of voices within us: One that is always encouraging. The one that says, “Yes, you can do it” and…..Another that is always discouraging. That one always throws negatives at us. How we view the world is often how we see it. The result is in the voice we project. Vincent Van Gogh remarked, “If you hear a voice within you say ‘you cannot paint,’ then by all means paint, and that voice will be silenced.”

Stop blocking your abilities to dominate. As human beings, we are blessed with a choice to silence one of those voices and encourage the other. Negative, being automatic is easy to adapt. But it is always a choice to make – consciously! Today, begin to use your voice powerfully. It has creative power to shape your world and those you touch.

Share this…………become a ROOSTER and wake up the sleeping.

Sarah Elizabeth Stewart, PhD, MD (1905–1976 pictured below), whose discoveries involving the murine polyomavirus with Bernice Eddy, PhD, propelled the then-reluctant field of oncology to pursue viral etiologies of cancer.  They worked together at University of Chicago for three years which lead to her being recruited by Alton Ochsner for the New Orleans project to find a cure/solution to the contamination of the poliovirus by SV-40 in a secret lab at a US Public Service Hospital in New Orleans with Dr. Mary Sherman.

From my initial post mortem of data I have gathered from my contacts on the front line in New Orleans this virus is hijacking hemoglobin’s ability to carry oxygen to tissues.  The lung tissue then responds to this in a reactive way via imaging studies.

HYPERLINK

I don’t think this paper above is getting enough publicity right now in this pandemic. It helps explain why the COVID 19 hypoxia is unique in its presentation.  

The paper theorizes how and why coronavirus reduces blood O2 and causes “crushed glass” lung imagery. This happens because the virus attacks the beta chains of hemoglobin and this binding appears to kick out heme from RBCs rendering them unable to deliver oxygen to mitochondria. The risk factors of high A1C, blood sugar, high LDH and ferritin, and why certain treatments work. (Hydroxychlorquine)

One clinical pearl I have heard from all my MD friends on the front line in NOLA is “Very often, extreme fatigue hits first.” PEEP and blood transfusions are not helpful. My bet is RBC transfusion won’t work well in patients who are actively shedding virus because the virus will immediately attack the new transfused RBC mimicking graft versus host disease response. COVID viral genes 1 and 8 have been predicted to interfere with heme synthesis.

Heme synthesis first step occurs in the mitochondria. So if it is disrupted this virus compounds the situation. Heme is the red compound in blood and in cytochrome C oxidase, and catalase that carries oxygen and CO2.   When mitochondrial oxygen consumption slows more dissolved oxygen in the cell rises and this excess oxygen become substrate to make free radicals that further destroy the lipid membranes of mitochondria and RBCs to lead to the early fever, and cytokine storm seen in COVID19 via the NFLR3 inflammasome.

This destroys ATP formation by the ATPase and this causes extreme hypoxia that mimics suffocation or high altitude pulmonary exposure (HAPE). It appears once the virus attacks it acts by kicking out the iron and this gives a specific phenotype in the blood that mimics malaria. This explains why chloroquine seems effective as a treatment. Why would azithromycin help augment hydroxychloroquine? Azithromycin appears to be effective in the treatment of COPD through its suppression of inflammatory processes.  Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. Nucleic acid synthesis is not affected.

During a viral sepsis acid base balance is altered and most people become very acidotic. Azithromycin is an acid-stable antibiotic so its efficacy would not be altered in the face of metabolic or respiratory acidosis. This is why it has efficacy in COVID 19. It is one of the few antibiotics that can work in low pH environments. Due to its high concentration in phagocytes, azithromycin is actively transported to the site of infection. During active phagocytosis, large concentrations are released. The concentration of azithromycin in the tissues can be over 50 times higher than in plasma due to ion trapping and its high lipid solubility.

The damage to the beta chains of hemoglobin by COVID mimics malaria. Malaria also causes an inactivation of RBC to carry oxygen to mitochondria.  Malaria is an acute form of hemolytic anemia.  These types of anemia have symptoms that are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the acute breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones and pulmonary hypertension.

It appears COVID 19 happens so fast jaundice and gallstone do not have enough time to form but the pulmonary hypertension manifests as the key feature of the disease acutely.  The hemolysis can occur inside the vessels or outside the vessels.  I believe in COVID 19 it is an extravascular hemolysis that is operational.  Extravascular hemolysis refers to hemolysis taking place in the liver, spleen, bone marrow, and lymph nodes.  In this case very little hemoglobin escapes into blood plasma.

This is why no one is reporting jaundice in COVID 19 patients.

Pulmonary hypertension is a condition of increased blood pressure within the arteries of the lungs.  Symptoms include shortness of breath, syncope, tiredness, chest pain, swelling of the legs, and a fast heartbeat.

All of these symptoms are found in COVID 19 patients.

Extreme fatigue is a sign of HYPOXIA = HIF-alpha-1 = serious over use of thiamine which is a beacon of a loss of mitochondrial redox power no TCA use = lack of delta psi.  Without delta psi no new heme can be to replace hemoglobin or cytochrome C oxidase or catalase.  This explains why people present the way they do in the ER.

Here is a report from a NOLA ER doc who graduated LSU in 1998.

Clinical course is predictable.

“2-11 days after exposure (day 5 on average) flu like symptoms start. Common are fever, headache, dry cough, myalgias(back pain), nausea without vomiting, abdominal discomfort with some diarrhea, loss of smell, anorexia, fatigue.

Day 5 of symptoms- increased SOB, and bilateral viral pneumonia from direct viral damage to lung parenchyma.

Day 10- Cytokine storm leading to acute ARDS and multiorgan failure. You can literally watch it happen in a matter of hours.

81% mild symptoms, 14% severe symptoms requiring hospitalization, 5% critical.

Patient presentation is varied. Patients are coming in hypoxic (even 75%) without dyspnea. I have seen Covid patients present with encephalopathy, renal failure from dehydration, DKA. I have seen the bilateral interstitial pneumonia on the xray of the asymptomatic shoulder dislocation or on the CT’s of the (respiratory) asymptomatic polytrauma patient. Essentially if they are in my ER, they have it. Seen three positive flu swabs in 2 weeks and all three had Covid 19 as well. Somehow this VIRUS has told all other disease processes to get out of town. This shows you how the virus is causing a loss of medical capacity inside the hospital.

China reported 15% cardiac involvement. I have seen covid 19 patients present with myocarditis, pericarditis, new onset CHF and new onset atrial fibrillation. I still order a troponin, but no cardiologist will treat these heart attacks (STEMI) no matter what the number in a suspected Covid 19 patient. Even our non covid 19 STEMIs at all of our facilities are getting TPA in the ED and rescue PCI at 60 minutes only if TPA fails.

Diagnostic

CXR- bilateral interstitial pneumonia (anecdotally starts most often in the RLL so bilateral on CXR is not required). The hypoxia does not correlate with the CXR findings. Their lungs do not sound bad. Keep your stethoscope in your pocket and evaluate with your eyes and pulse ox.

Labs- WBC low, Lymphocytes low, platelets lower then their normal, Procalcitonin normal in 95%

CRP and Ferritin elevated most often. CPK, D-Dimer, LDH, Alk Phos/AST/ALT commonly elevated.

Notice D-Dimer- I would be very careful about CT PE these patients for their hypoxia. The patients receiving IV contrast are going into renal failure and on the vent sooner.

Basically, if you have a bilateral pneumonia with normal to low WBC, lymphopenia, normal procalcitonin, elevated CRP and ferritin- you have covid-19 and do not need a nasal swab to tell you that.

A ratio of absolute neutrophil count to absolute lymphocyte count greater than 3.5 may be the highest predictor of poor outcome. the UK is automatically intubating these patients for expected outcomes regardless of their clinical presentation.

An elevated Interleukin-6 (IL6) is an indicator of their cytokine storm. If this is elevated watch these patients closely with both eyes.

Other factors that appear to be predictive of poor outcomes are thrombocytopenia and LFTs 5x upper limit of normal.

Disposition

I had never discharged multifocal pneumonia before. Now I personally do it 12-15 times a shift. 2 weeks ago we were admitting anyone who needed supplemental oxygen. Now we are discharging with oxygen if the patient is comfortable and oxygenating above 92% on nasal cannula. We have contracted with a company that sends a paramedic to their home twice daily to check on them and record a pulse ox. We know many of these patients will bounce back but if it saves a bed for a day we have accomplished something. Obviously we are fearful some won’t make it back.

We are a small community hospital. Our 22 bed ICU and now a 4 bed Endoscopy suite are all Covid 19. All of these patients are intubated except one. 75% of our floor beds have been cohorted into covid 19 wards and are full. We are averaging 4 rescue intubations a day on the floor. We now have 9 vented patients in our ER transferred down from the floor after intubation.

Luckily we are part of a larger hospital group. Our main teaching hospital repurposed space to open 50 new Covid 19 ICU beds this past Sunday so these numbers are with significant decompression. Today those 50 beds are full. They are opening 30 more by Friday. But even with the “lockdown”, our AI models are expecting a 200-400% increase in covid 19 patients by 4/4/2020. “

That is the clinical view from New Orleans now.

If the patient isn’t showing signs of respiratory difficulty but has extreme fatigue, one thing to question is whether the oxygen is getting from lungs to body tissues.

This would lead to organ and tissue death, roughly in the same way as if a patient were being suffocated.

Even when a patient can breath (fill lungs with air), the oxygen isn’t getting to the colony of mitochondria in the cells in their body.

Similiarities between COVID 19 and High Altitude Pulmonary Edema

HAPE symptoms similar to covid: “HAPE was misdiagnosed for centuries, as evidenced by frequent reports of young, vigorous men suddenly dying of “pneumonia” within days of arriving at high altitude.”

HAPE’s mechanism results from low amounts of ambient atmospheric oxygen, so the subject’s blood is unable to bring enough oxygen to the body.

Nothing is “attacking” the lungs, but the lungs show similar inflammatory symptoms to COVID, because O2 in blood is low. Remember UV light exposure increases venous O2.

This would lead to organ and tissue death, roughly in the same way as if a patient were being suffocated.

Even when a patient can breath (fill lungs with air), the oxygen isn’t getting to the cells in their body.

The inflammation in the lungs results from the lungs not being able to perform the oxygen/CO2 exchange, and would therefore appear to be a SECONDARY result of the hijacking of the blood.

The lungs not working is a result of lack of O2 in blood, not the cause of it.  It might be a disease of heme.  

The reason why technology use exacerbates the disease because it also causes defects in RBC synthesis by blocking heme formation by causing mitochondrial damage. (pic below)

Several paper reviewed on drug models the behavior of chloroquine and faviparavir as well, which appear to bind to the non-structural viral proteins that hijack the heme groups, thus inhibiting them from knocking out the iron and wrecking the O2-carrying ability of the red blood cells.

This also explains the observation made by various ER docs that patients tend to have elevated ferritin: ferritin is used to store excess iron released from the RBC damage. If a lot of iron is knocked out of heme groups and floating around, the body produces more ferritin.

In humans, it acts as a buffer against iron deficiency and iron overload. This overlaod happens hyperacutely in COVID19.   Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia. This anemia can happen acutely or chronically.

If this mechanism of damage is true, this implies we need to think a lot differently than we are now:

1. Starting drug treatment while symptoms are mild keeps virus from hijacking too much of the RBC and cytochrome C oxidase, or catalase, enabling a still-healthy body to mount an immune response. Plasma therapies should be done before RBC transfusions.

This explains why early drug treatment (first week of symptoms) is often successful. It stabilizes iron metabolism and stabilzes CO2/O2 delivery early on and maintains mitochondrial function via cytochrome C oxidase. This preserves ATP function. Red light therapy would augment this affect.  Nitric oxide mimicry might save cytochrome c oxidase.  This might be why UV light helps limit COVID 19 cases.  UV light increases the production of nitric oxide and this shuts down the use of cytochrome c oxidase.

This would explain why all coronavirus seem to be inactive in summer months.

2. Drug treatment and intubation once patient is critical these option will rarely work because tissues/organs are already damaged by viral destruction of the beta chain of hemoglobin; therefore, blood can’t carry O2, and the body is too weak to produce new red blood cells able to carry iron (and thus oxygen/CO2) even if drugs inhibit more hijacking.

3. Thus: start severe patients on drug treatment upon hospital intake to suppress further hijacking of blood by the virus, then give them a blood transfusion of new red blood cells immediately that are unhijacked.

4. If heme/hemoglobin is involved, a higher hemoglobin count may be protective to the disease process.  This may explain why nicotine helps.  It maybe that’s why smokers are so underrepresented in the data.  Their chronic hypoxia from smoking increases their hemoglobin counts.   This also would also predict less severe acute mitochondrial failure from COVID 19 disease in high altitude populations.  The Johns Hopkins map supports this.  Nairobi is untouched. 

5. Hypoxia explains the loss of taste and smell too.  We know that the human olfactory receptor becomes less sensitive under hypoxic hypoxia.  HYPERLINK

CONCLUSIONS:

If all this is true, we would see rapid patient improvement with the use of plasma first. The reason for many cases of recrashing with COVID might be due to an inability to recovery the ability to make new heme because of the mitochondrial damage. People forget heme synthesis begins in the mitochondrial matrix. This implies we should consider RBC transfusion later in the disease during recovery.

These ideas should be very testable in the hospital environment now.

Also, if it’s true, we’re gonna need a lot of blood donations after the acute phase of viral attack.

So far as I know, there are no studies where we’ve tried transfusing blood from a patient who HASN’T had or recovered from COVID-19.

We can verify/disprove this by comparing outcomes between plasma-only and full blood transfusion (and control), or just between blood transfusion vs control (both should be given hydroxychloroquine. It appears the hydroxychloroquin is a heme salvage operation before acute infection and beta chain destruction.

So for ER/ICU/hospitalists MD’s handling incoming severe patients with multi-organ system failure that we consider early plasma therapies to protect all heme proteins and later blood transfusion with supportive care to deliver oxygen to mitochondria in tissues that are undergoing acute mitochondrial colony failure.  

CITES:

1. https://www.click2houston.com/news/local/2020/03/29/houston-methodist-first-in-nation-to-be-approved-by-fda-to-transfuse-donated-plasma-from-recovered-covid-19-patient/

2. https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173

3. https://jamanetwork.com/journals/jama/fullarticle/2763983

4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617508/

The media and politicians are obsessed about the number of ventilators available.  Is this wise?

Obsession is the single most wasteful human activity, because with an obsession you keep coming back and back and back to the same question and never get an answer. An obsession is a way for damaged people to damage themselves more.

What about these ideas:  are they worth considering now?

1. What about the number of people who are skilled to manage ventilated patients?  it is not a basic medical skill?

2. Have you ever contemplated what the sheer quantity of analgesics, sedatives and paralytics needed to treat ventilated patients is in a pandemic?  The public has no clue what a loss of medical capacity looks like much less what it feels like to a person on the front line.  Beware of false knowledge; it is more dangerous than ignorance. Ignorance is always afraid of adaptation, because thinking is heavy lifting for the unripe mind.  The data shows us that already our beliefs might be wrong…….about what is really afoot in the world tonight

3.  This year we are told the interventions we use to stabilize folks are not “safe” if have Covid 19. We won’t know result for 24hrs due to testing constraints. So in this situation should we deny life saving treatment? In a true disaster-yes. But is this axiom still true in a flattened curve situation?

4. Instead of black and white situation we’re  dealing with 150 shades of grey.  No one has an answer because too few can think about the asymmetry of the situation clearly.   The surreal part of this pandemic, I think, comes when you’re thrown into a situation that you’ve never been in before. It’s extremely disorienting to those who expect normalcy.   Right now, many of the patterns we know and love have been obliterated. We can’t go to happy hour, we can’t get toilet paper when we want it, we can’t plan our annual vacation getaway.

5. Highest number of nurses = lowest death rate = Germany.  Note it is nurses and not doctors that are the key to your survival in some areas.

6. The study of the surreal has mostly concerned Dali’s paintings and Kafka’s writings. But there are psychological reasons why every day during a pandemic seems so otherworldly.  What happens when all of a sudden the whole world follows the same narrative as the plot unfolds and nobody has a clue what the next scene is gonna be like, or what the end will be?

7. It’s like there’s no future, because we cannot plan for a future in abject chaos.  People are afraid of chaos.  Few see opportunity in its randomness.  The upending of our normal lives also obliterated the routines, however mundane, that keep the average person levelheaded.  Why do so many shoot for average in life? A man who wants to lead the orchestra must turn his back on the crowd and their beliefs at times.

8. The imaginary of nature capabilities is what tends to become real in life.  We must begin to realize the black swan event is normal and not an outlier.  Normalcy is so toxic it’s made a majority of people in the modern world “normally” unhealthy, “normally” neurotic, “normally” gullible…long before this crisis.  Normalcy never was, never will be your friend.   QUESTION IT.

9.  Nothing that surrounds us is objective, and all around us is subjective to the environment we have created in the zipcode we inhabit by choice.  We are deluded by routine.  Most believe their routine is the scaffolding of life, because it’s how we organize information and our time. And without it, we can feel really lost.  People hate feeling lost.  The truth is stranger than our beliefs.  Just because someone stumbles and loses their path, doesn’t mean they’re lost.  They maybe acutely lost but they are not lost forever.  There’s always time to change the road your on, even in total chaos.

10.  Reality is obtained by Nature by slightly bending physical and chemical laws using probabilities.  This is why quantum mechanics is Nature’s language.

Rather than imagining life is a solo performance, Begin to create a tune that becomes part of a vast choral production the Universe has been singing since our primitive ancestors first looked towards the heavens. Realize our lives were part of a vocal symphony directed by a “cosmic composer” who is putting together a grand concert from musical threads supplied by every individual. Living optimally is a team game. Individuals may win the game at times, but teams win championships in life.  We’re all in this chaos together.

What is the ultimate cure of all diseases? Increasing your redox power via sunlight. We all need some Purple rain (UV/IR-A) from the sun to come upon us. Never forget it my Black Swans.

Here is the truth about life…..your current situation is never permanent. It is what you make of it from your choices. Life is not solid it is fluid and it always changes.

Night Swans……….